ABSTRACT
The aim of study is to identify pathomorphological changes of the Central nervous system in childhood with rarely diagnosed of «baby shaking¼ syndrome on the example of sectional case. The analysis of medical documentation (medical history and outpatient card of the child) was done. The standard method of opening the skull cavity of infants was used. Histological cuts of autopsy material were treated with hematoxilin-eosin coloring. The relationship of clinical and morphological manifestations of this pathology with anatomical and physiological features of the structure of the Central nervous system and its blood supply in children was stated. We describe in details the characteristic pathomorphological changes in the brain in childhood that occur with this syndrome. Dark red «flattened¼ blood coagulations of subtentorial localization and in the left convexital region were visualized in the cranial cavity. We paid attention to the presence of numerous bridge veins of the brain, flowing into the sagittal sinus (frontal and parietal) and the transverse sinus.
Subject(s)
Brain , Shaken Baby Syndrome , Brain/pathology , Child , Humans , Infant , Shaken Baby Syndrome/diagnosisABSTRACT
The influence of bone marrow autotransplantation on neurotransmitter structures of appendix vermiformis was studied. The study revealed that an increase in the number of neurotransmitter structures (mast and granular luminescent cells), having a high content of catecholamines and serotonin was noted in old rats in 40 min after bone marrow autotransplantation. In the center of vermiformis appendix lymphoid nodes reproduction cellular programmed differentiations having a high content of neuroamines are determined. In 2 hours after bone marrow autotransplantation their number decreases, the content of catecholamines and serotonin reduces as well. In the immunohistochemical reaction increase in proliferative activity of cells both in proper t. mucosa plate crypts and appendix vermiformis lymphoid nodules is observed up to 40 min of experiment. In 2 hours Ki-67 positive cells reduce both in t. mucosa and t. s/mucosa of appendix vermiformis.
