ABSTRACT
A sample of patients (N = 134) with alcoholic liver disease was found to be significantly "health internal" (i.e., believe that their behavior plays a major role in determining subsequent health or illness) compared with a sample of patients with nonalcoholic liver disease on Health Locus of Control Scale. The patients with alcoholic liver disease did not differ significantly from those with nonalcoholic liver disease in the level of awareness of severity of their disease. Most patients in both groups agreed with their physician's ratings of the severity of their illness. The implications of these findings are discussed.
Subject(s)
Liver Diseases, Alcoholic/psychology , Perception , Severity of Illness Index , Adolescent , Adult , Alcohol Drinking/psychology , Awareness , Female , Humans , Male , Middle Aged , Self-AssessmentABSTRACT
Factor analysis of the Crown-Crisp Experiential Index (CCEI) is described. Two groups took part in the study; one from a working population (n = 8292) and one from clients attending three Employment Rehabilitation Centres (n = 281). Comparison of the factors obtained from these two groups, and between these and the original CCEI subscales, are reported, together with estimates of reliability. Overall, the results point to the retention of the CCEI as a reliable instrument for measuring psychoneurotic illness.
Subject(s)
Neurotic Disorders/diagnosis , Psychological Tests , Adolescent , Adult , Age Factors , Aged , Anxiety Disorders/diagnosis , Depressive Disorder/diagnosis , Female , Humans , Hysteria/diagnosis , Male , Middle Aged , Neurotic Disorders/psychology , Obsessive-Compulsive Disorder/diagnosis , Phobic Disorders/diagnosis , Psychometrics , Sex FactorsABSTRACT
1 Patients on prolonged treatment with anticonvulsant and phenothiazine drugs exhibited lower than normal concentrations of folate in serum and erythrocytes, and showed increased urinary FIGLU excretion after histidine loading; urinary excretion of D-glucaric acid was also increased suggesting induction of the hepatic microsomal enzymes. 2 Folate deficiency by enzyme-inducing drugs was seen to be determined more by the duration of therapy than by the nature of the drugs. Excretion of FIGLU was increased by 70% by 2-5 years of treatment with anticonvulsant, phenothiazine or tricyclic drugs, and by 200% after 6 or more years. 3 Hepatic microsomal enzyme induction, as measured by D-glucaric acid excretion, was greatest after 2-5 years treatment. 4 It is suggested that the increased requirements for folate, resulting from microsomal enzyme induction, lead to folate deficiency and this subsequently limits enzyme induction, leading to adverse drug side-affects. 5 The dietary folate of hospitalized patients would seem to be generally inadequate for patients on long term treatment with enzyme-inducing drugs.
