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J Digit Imaging ; 21(1): 27-36, 2008 Mar.
Article in English | MEDLINE | ID: mdl-17333413

ABSTRACT

In this paper, a fast, slice-by-slice, nonrigid registration algorithm of dynamic magnetic resonance breast images is presented. The method is based on a multiresolution motion estimation of the breast using complex discrete wavelet transform (CDWT): the pyramid of oriented complex subimages is used to implement a hierarchical phase-matching-based motion estimation algorithm. The resulting motion estimate is nonrigid and pixel-independent. To assess the method performance, we computed the correlation coefficient and the normalized mutual information between pre- and postcontrast images with and without realignment. The indices increased after using our approach and the improvement was superior to rigid or affine registration. A set of clinical scores was also evaluated. The clinical validation demonstrated an increased readability in the subtraction images. In particular, CDWT registration allowed a best definition of breast and lesion borders and greater detail detectability.


Subject(s)
Algorithms , Breast Neoplasms/diagnosis , Contrast Media , Image Processing, Computer-Assisted , Magnetic Resonance Imaging , Breast Neoplasms/diagnostic imaging , Female , Humans , Image Processing, Computer-Assisted/methods , Magnetic Resonance Imaging/methods , Radiography
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