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1.
Zh Evol Biokhim Fiziol ; 29(1): 32-7, 1993.
Article in Russian | MEDLINE | ID: mdl-8498111

ABSTRACT

Biochemical and morphometric analyses have been made of the effects of nonapeptide neurohormones, vasotocin and mesotocin, on the chromaffin tissue of the adrenal gland of the frog, both in vivo and in vitro experiments. It was shown that vasotocin exerts stimulating effect on the suprarenal gland whereas mesotocin inhibits the latter. In vitro experiments revealed that adrenalin may abolish the effect of nonapeptides on the suprarenal gland.


Subject(s)
Adrenal Glands/drug effects , Oxytocin/analogs & derivatives , Vasotocin/pharmacology , Adrenal Glands/anatomy & histology , Adrenal Glands/metabolism , Animals , Cosyntropin/pharmacology , Dose-Response Relationship, Drug , Drug Interactions , Epinephrine/pharmacology , In Vitro Techniques , Male , Oxytocin/pharmacology , Rana temporaria
2.
Zh Evol Biokhim Fiziol ; 28(5): 605-10, 1992.
Article in Russian | MEDLINE | ID: mdl-1300018

ABSTRACT

Morphometric studies indicate that vasotocin increases the activity of the adrenal gland in frogs, whereas mesotocin and epinephrine do not essentially affect it. Combination of epinephrine with nonapeptides in cultural medium showed that the former may abolish the effect of vasotocin on the adrenal gland.


Subject(s)
Epinephrine/pharmacology , Interrenal Gland/drug effects , Oxytocin/analogs & derivatives , Vasotocin/pharmacology , Animals , Cosyntropin/pharmacology , Dose-Response Relationship, Drug , In Vitro Techniques , Interrenal Gland/cytology , Male , Oxytocin/pharmacology , Rana temporaria
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