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1.
Article in English | MEDLINE | ID: mdl-38689385

ABSTRACT

BACKGROUND: While gun injuries are more likely to occur in in urban settings and affect people of color, factors associated with gun violence revictimization-suffering multiple incidents of gun violence-are unknown. We examined victim demographics and environmental factors associated with gun violence revictimization in New York state (NYS). METHODS: The 2005-2020 NYS hospital discharge database was queried for patients aged 12-65 years with firearm-related hospital encounters. Patient and environmental variables were extracted. Patient home zip code was used to determine the Social Deprivation Index (SDI) for each patient's area of residence. We conducted bivariate and multivariate analyses among patients who suffered a single incident of gun violence or gun violence revictimization. RESULTS: We identified 38,974 gun violence victims among whom 2,243 (5.8%) suffered revictimization. The proportion of revictimization rose from 4% in 2008 to 8% in 2020 (p < 0.01). The median [IQR] time from first to second incident among those who suffered revictimization was 359 [81-1,167] days. Revictimization was more common among Blacks (75.0% vs 65.1%, p < 0.01), patients with Medicaid (54.9% vs 43.2%, p < 0.01), and in areas of higher deprivation (84.8 percentile vs 82.1 percentile, p < 0.01). CONCLUSIONS: Gun violence revictimization is on the rise. People of color and those residing in areas with high social deprivation are more likely to be re-injured. Our findings emphasize the importance of community-level over individual-level interventions for prevention of gun violence revictimization. LEVEL OF EVIDENCE: Epidemiological, Level III.

2.
J Mech Behav Biomed Mater ; 125: 104930, 2022 01.
Article in English | MEDLINE | ID: mdl-34781225

ABSTRACT

Identification of burn depth with sufficient accuracy is a challenging problem. This paper presents a deep convolutional neural network to classify burn depth based on altered tissue morphology of burned skin manifested as texture patterns in the ultrasound images. The network first learns a low-dimensional manifold of the unburned skin images using an encoder-decoder architecture that reconstructs it from ultrasound images of burned skin. The encoder is then re-trained to classify burn depths. The encoder-decoder network is trained using a dataset comprised of B-mode ultrasound images of unburned and burned ex vivo porcine skin samples. The classifier is developed using B-mode images of burned in situ skin samples obtained from freshly euthanized postmortem pigs. The performance metrics obtained from 20-fold cross-validation show that the model can identify deep-partial thickness burns, which is the most difficult to diagnose clinically, with 99% accuracy, 98% sensitivity, and 100% specificity. The diagnostic accuracy of the classifier is further illustrated by the high area under the curve values of 0.99 and 0.95, respectively, for the receiver operating characteristic and precision-recall curves. A post hoc explanation indicates that the classifier activates the discriminative textural features in the B-mode images for burn classification. The proposed model has the potential for clinical utility in assisting the clinical assessment of burn depths using a widely available clinical imaging device.


Subject(s)
Burns , Deep Learning , Animals , Burns/diagnostic imaging , Neural Networks, Computer , Skin/diagnostic imaging , Swine , Ultrasonography
3.
Surg Innov ; 28(2): 220-225, 2021 Apr.
Article in English | MEDLINE | ID: mdl-33780641

ABSTRACT

Introduction. Teaching surgical skills has historically been a hands-on activity, with instructors and learners in close physical proximity. This paradigm was disrupted by the COVID-19 pandemic, requiring innovative solutions to surmount the challenges of teaching surgical skills remotely. In this work, we describe our institution's path and early results of developing an interactive remote surgical skills course for medical students in the surgical clerkship. Methods. 31 third-year medical students were distributed a set of surgical equipment and 3D printed phone dock. Each participant completed a baseline questionnaire and underwent 3 structured interactive remote sessions on surgical instruments, knot tying, and suturing techniques. Students were instructed on sharing their first-person viewpoint and received real-time feedback on their knot tying and suturing techniques from the course instructor. Pre- and post-session surveys were conducted and analyzed. Results. All students were able to complete the remote surgical skills course successfully, as defined by visually demonstrating successful two-handed knot and simple suture techniques. Students' aggregate confidence score in their knot tying ability (pretest mean 7.9, SD 0.7 vs posttest mean 9.7, SD 0.9, t-statistic -2.3, P = .03) and suturing ability (pretest mean 8.0, SD 1.3 vs posttest mean 13.8, SD 0.9 t-statistic -5.5, P < .001) significantly improved after the intervention. Qualitative feedback from the students underscored the utility of the first-person perspective for teaching surgical technique. Conclusion. This study demonstrates that remote teaching of knot tying and simple suturing to medical students can be effectively implemented using a remote learning curriculum that was well received by the learners.


Subject(s)
COVID-19 , Education, Distance , General Surgery/education , Students, Medical , Curriculum , Humans , Pandemics , SARS-CoV-2 , Simulation Training , Suture Techniques/education
4.
Am J Surg ; 221(2): 298-302, 2021 02.
Article in English | MEDLINE | ID: mdl-33189315

ABSTRACT

INTRODUCTION: In order to recruit high-potential trainees, surgery residency and fellowship programs must first understand what competencies and attributes are required for success in their respective programs. This study performed a systematic analysis to define organizational culture and competency expectations across training programs within one academic surgery department. METHODS: Subject matter experts rated the importance and frequency of 22 competencies and completed a 44-item organizational culture inventory along 1 to 5 Likert-type scales. RESULTS: Importance and frequency attributions of competencies varied significantly among programs (p < .05 by ANOVA), but there was substantial agreement on organizational culture; self-directed (x̄ = 3.8), perfectionist (x̄ = 3.7) and social (x̄ = 3.7) attributes were most representative of the program, while oppositional (x̄ = 1.8), competitive (x̄ = 2.5) and hierarchical (x̄ = 2.7) characteristics were least representative. CONCLUSIONS: Residency and fellowship programs within the same department have shared perceptions of the culture and values of their institution, but seek different competencies among entering trainees.


Subject(s)
Academic Medical Centers/organization & administration , Clinical Competence/standards , Organizational Culture , Personnel Selection/standards , Surgery Department, Hospital/organization & administration , Academic Medical Centers/standards , Fellowships and Scholarships/standards , Internship and Residency/standards , Motivation , Surgery Department, Hospital/standards
5.
Am J Surg ; 220(5): 1323-1326, 2020 11.
Article in English | MEDLINE | ID: mdl-32660698

ABSTRACT

BACKGROUND: Atorvastatin could be beneficial in the treatment of burn patients to prevent burn wound progression from partial to full thickness. Our primary aim is to evaluate the safety of atorvastatin in burn patients. METHODS: Single center retrospective chart review of burn patients receiving atorvastatin during admission May 2016-May 2019 with historic controls was performed. Demographics, burn total body surface area, atorvastatin doses, creatinine phosphokinase, aspartate aminotransferase levels and adverse events were analyzed. RESULTS: 48 burn patients received atorvastatin during admission. Nine patients experienced elevated CK or AST levels during admission, but did not correlate with timing of atorvastatin administration and were comparable to levels in control patients. No adverse events associated with atorvastatin were identified. CONCLUSIONS: Atorvastatin administered to patients with burn injuries was not associated with any adverse events or attributable lab abnormalities. We believe that atorvastatin is safe to use in patients with burns and can be safely studied to determine the drug's effect on the prevention of burn wound conversion.


Subject(s)
Atorvastatin/therapeutic use , Burns/drug therapy , Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use , Wound Healing , Adult , Aged , Aged, 80 and over , Burns/physiopathology , Female , Humans , Male , Middle Aged , Retrospective Studies , Trauma Severity Indices , Treatment Outcome
6.
J Vasc Surg ; 72(6): 2130-2138, 2020 12.
Article in English | MEDLINE | ID: mdl-32276021

ABSTRACT

OBJECTIVE: Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) reduce the risk of cardiovascular events in patients with peripheral artery disease. However, their effect on limb-specific outcomes is unclear. The objective of this study was to assess the effect of ACE inhibitors/ARBs on limb salvage (LS) and survival in patients undergoing peripheral vascular intervention (PVI) for chronic limb-threatening ischemia (CLTI). METHODS: The Vascular Quality Initiative registry was used to identify patients undergoing PVI for CLTI between April 1, 2010, and June 1, 2017. Patients with complete comorbidity, procedural, and follow-up limb and survival data were included. Propensity score matching was performed to control for baseline differences between the groups. LS, amputation-free survival (AFS), and overall survival (OS) were calculated in matched samples using Kaplan-Meier analysis. RESULTS: A total of 12,433 limbs (11,331 patients) were included. The ACE inhibitors/ARBs group of patients had significantly higher prevalence of coronary artery disease (31% vs 27%; P < .001), diabetes (67% vs 57%; P < .001), and hypertension (94% vs 84%; P < .001) and lower incidence of end-stage renal disease (7% vs 12%; P < .001). Indication for intervention was tissue loss in 64% of the ACE inhibitors/ARBs group vs 66% in the no ACE inhibitors/ARBs group (P = .005). Postmatching survival analysis at 5 years showed improved OS (81.8% vs 79.9%; P = .01) and AFS (73% vs 71.5%; P = .04) with ACE inhibitors/ARBs but no difference in LS (ACE inhibitors/ARBs, 88.3%; no ACE inhibitors/ARBs, 88.1%; P = .56). After adjustment for multiple variables in a Cox regression model, ACE inhibitors/ARBs were associated with improved OS (hazard ratio, 0.89; 95% confidence interval, 0.80-0.99; P = .03) and AFS (hazard ratio, 0.92; 95% confidence interval, 0.84-0.99; P = .04). CONCLUSIONS: ACE inhibitors/ARBs are independently associated with improved survival and AFS in patients undergoing PVI for CLTI. LS rates remained unaffected. Further research is required to investigate the use of ACE inhibitors/ARBs in this population of patients, especially CLTI patients with other indications for therapy with ACE inhibitors/ARBs.


Subject(s)
Angiotensin Receptor Antagonists/therapeutic use , Angiotensin-Converting Enzyme Inhibitors/therapeutic use , Endovascular Procedures , Ischemia/therapy , Peripheral Arterial Disease/therapy , Aged , Aged, 80 and over , Amputation, Surgical , Comorbidity , Endovascular Procedures/adverse effects , Endovascular Procedures/mortality , Female , Humans , Ischemia/diagnosis , Ischemia/mortality , Limb Salvage , Male , Peripheral Arterial Disease/diagnosis , Peripheral Arterial Disease/mortality , Registries , Retrospective Studies , Risk Assessment , Risk Factors , Time Factors , Treatment Outcome , United States/epidemiology
7.
Sci Rep ; 10(1): 5829, 2020 04 02.
Article in English | MEDLINE | ID: mdl-32242131

ABSTRACT

This article presents a real-time approach for classification of burn depth based on B-mode ultrasound imaging. A grey-level co-occurrence matrix (GLCM) computed from the ultrasound images of the tissue is employed to construct the textural feature set and the classification is performed using nonlinear support vector machine and kernel Fisher discriminant analysis. A leave-one-out cross-validation is used for the independent assessment of the classifiers. The model is tested for pair-wise binary classification of four burn conditions in ex vivo porcine skin tissue: (i) 200 °F for 10 s, (ii) 200 °F for 30 s, (iii) 450 °F for 10 s, and (iv) 450 °F for 30 s. The average classification accuracy for pairwise separation is 99% with just over 30 samples in each burn group and the average multiclass classification accuracy is 93%. The results highlight that the ultrasound imaging-based burn classification approach in conjunction with the GLCM texture features provide an accurate assessment of altered tissue characteristics with relatively moderate sample sizes, which is often the case with experimental and clinical datasets. The proposed method is shown to have the potential to assist with the real-time clinical assessment of burn degrees, particularly for discriminating between superficial and deep second degree burns, which is challenging in clinical practice.


Subject(s)
Burns/diagnostic imaging , Algorithms , Animals , Skin/diagnostic imaging , Support Vector Machine , Swine , Ultrasonography/methods
8.
Ann Vasc Surg ; 61: 246-253, 2019 Nov.
Article in English | MEDLINE | ID: mdl-31382009

ABSTRACT

BACKGROUND: Surgical revascularization is the mainstay treatment in treating most traumatic arterial injuries, and autologous great saphenous vein is widely regarded as the conduit of choice. However, the use of the great saphenous vein may be limited by many factors, and there are little data to guide management in this setting. Bovine carotid artery graft (Artegraft, Inc., North Brunswick, NJ, USA) is a biologic conduit that has been used in select trauma cases at our center. The objective of this study was to review and compare our experience with autologous vein and bovine carotid artery in traumatic arterial injuries requiring bypass or interposition. METHODS: This is a retrospective review of all patients with a traumatic arterial injury repaired with autologous vein or bovine carotid artery graft at a single center between April 2014 and October 2016. Outcomes of interest included differences in duration of ischemia, operative times, patency, limb salvage, graft-related complications, and functional status. RESULTS: Thirty patients were included in this study. Seventeen (57%) injuries were to the lower extremity (LE) and 13 (43%) to the upper extremity. Bovine carotid artery graft was used as a conduit in 12 (40%) cases, while autologous vein was used in 18 (60%) patients. Patients were predominantly male (90%). Mean age was 31 ± 15 years. Comorbidities did not differ significantly between the groups. Mean follow-up duration was 19 ± 13 months. Overall primary patency was 82%: bovine versus autologous vein (78% vs. 85%; P = 0.68). Overall secondary patency was 91%: bovine versus autologous vein (78% vs. 100%; P = 0.16). Overall limb salvage was 90%: bovine versus autologous vein (82% vs. 94%; P = 0.28). When comparing bovine carotid artery graft to autologous vein in LE interventions, primary patency (50% vs. 71%; P = 0.40), secondary patency (75% vs. 100%; P = 0.23), and limb salvage (80% vs. 86%; P = 0.76) did not differ significantly. There were no early or late graft infections with either conduit. There were no significant differences in ambulatory status at discharge by graft type. Overall survival was 100%. CONCLUSIONS: In this series, there is a trend toward improved patency and limb salvage with autologous vein. Autologous vein should be the standard of care for revascularization of traumatic arterial injuries. Bovine carotid artery graft appears be a viable alternative, especially in patients requiring urgent revascularization, that does not significantly compromise patency, limb salvage, or functional outcomes.


Subject(s)
Carotid Arteries/transplantation , Vascular Grafting , Vascular System Injuries/surgery , Veins/transplantation , Adolescent , Adult , Animals , Autografts , Carotid Arteries/diagnostic imaging , Carotid Arteries/physiopathology , Cattle , Female , Graft Survival , Heterografts , Humans , Limb Salvage , Male , Middle Aged , Operative Time , Postoperative Complications/etiology , Retrospective Studies , Risk Factors , Time Factors , Treatment Outcome , Vascular Grafting/adverse effects , Vascular Patency , Vascular System Injuries/diagnostic imaging , Vascular System Injuries/physiopathology , Veins/diagnostic imaging , Veins/physiopathology , Young Adult
9.
J Crit Care ; 30(6): 1222-6, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26271687

ABSTRACT

OBJECTIVES: Endotracheal self-extubation (ESE) is a serious health care concern. We designed this study to test our hypothesis that not all patients with ESE are successful in spontaneous breathing and reintubation has negative impact on outcomes. METHODS: Data on all 39 patients of ESE in our surgical and trauma intensive care unit (ICU) in 2012 were prospectively collected and retrospectively analyzed. RESULTS: There were 42 episodes of ESE in 39 of 939 intubated patients (frequency, 4.0%), with 54% of events requiring reintubation. Pre-ESE positive end-expiratory pressure was higher and Pao2/fraction of inspired oxygen ratio was lower, and the post-ESE respiration rate was higher in the reintubated group. On univariate analysis, weaning and spontaneous breathing trial before ESE were favorable predictors for nonreintubation. Multivariate regression analysis demonstrated that agitation before ESE was an independent predictor of reintubation. The need for reintubation was associated with increased risk of pulmonary infectious complications, ventilator days, the need for tracheostomy, and ICU and hospital LOS. The financial costs for ventilator days and ICU rooms were significantly higher in patients with reintubation. CONCLUSION: Not all patients were fine after ESE. We have not decreased the frequency of ESE or improved outcomes if the patients were reintubated. The need for reintubation was not only associated with a high pulmonary complication rate but also prolonged duration on mechanical ventilation and hospital/ICU stay and increased the hospital costs.


Subject(s)
Airway Extubation/methods , Intubation, Intratracheal/statistics & numerical data , Respiration, Artificial/statistics & numerical data , Adult , Aged , Airway Extubation/statistics & numerical data , Female , Humans , Intensive Care Units/statistics & numerical data , Length of Stay/statistics & numerical data , Male , Middle Aged , Positive-Pressure Respiration/statistics & numerical data , Regression Analysis , Respiratory Rate/physiology , Retrospective Studies , Tracheostomy/statistics & numerical data
10.
Vascular ; 13(4): 244-7, 2005.
Article in English | MEDLINE | ID: mdl-16229799

ABSTRACT

A Baker's or popliteal cyst is a synovial cyst in the popliteal fossa arising from the knee joint. The majority of patients develop a popliteal mass that is asymptomatic, but in a small percentage of patients, complications and symptoms occur; these may not only encompass the popliteal veins and arteries but may also include cyst leakage, infection, hemorrhage, and compartment syndrome. Severe lower limb ischemia caused by a Baker's cyst is extremely rare, having been reported only six times since 1960; all patients were treated with surgical intervention. We report the case of a 29-year-old male presenting with right calf claudication caused by a Baker's cyst. The patient was managed nonoperatively with nonsteroidal anti-inflammatory agents, proper exercises, and close observation. His claudication improved progressively and had completely disappeared at 12 months of follow-up. A repeat duplex arterial study showed that increased blood flow to the right foot and the right ankle/brachial index improved to 0.97 from 0.67. Repeat ultrasonography demonstrated that the size of the cyst decreased from 4.5 x 1.5 cm to 2.8 x 0.9 cm. The patient had been followed for 20 months and remained asymptomatic in the last 8 months. We will continue to follow the patient to evaluate the long-term outcome. In summary, our own data and literature review suggest that the limb ischemia caused by Baker's cyst may be a transient condition and can be managed nonoperatively in selected patients.


Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Intermittent Claudication/drug therapy , Popliteal Cyst/complications , Adult , Constriction, Pathologic , Humans , Intermittent Claudication/diagnosis , Intermittent Claudication/etiology , Knee Joint/pathology , Magnetic Resonance Imaging , Male , Popliteal Cyst/diagnosis , Treatment Outcome
11.
J Trauma ; 58(3): 561-70, 2005 Mar.
Article in English | MEDLINE | ID: mdl-15761352

ABSTRACT

BACKGROUND: Substance abuse is associated with injuries, but these associations have not been well characterized by type of substance and injury type. METHODS: A cross-sectional study of patients selected for toxicology screening compared those with positive and those with negative test results for drugs and alcohol. RESULTS: Patients with positive alcohol toxicology results were more likely to have violence-related and penetrating injuries than patients with negative results. However, after adjustment for positive cocaine toxicology results, the association between alcohol and penetrating injury was no longer significant. Positive test results for any drug were not associated with any specific injury type, but cocaine was independently associated with violence-related injury. The associations of alcohol and cocaine with violence-related injury appear to be additive. In contrast, opiates were independently associated with nonviolent injuries and burns. CONCLUSIONS: Alcohol and cocaine use is independently associated with violence-related injuries, whereas opiate use is independently associated with nonviolent injuries and burns.


Subject(s)
Hospitalization/statistics & numerical data , Mass Screening/methods , Substance Abuse Detection/methods , Substance-Related Disorders/diagnosis , Substance-Related Disorders/epidemiology , Wounds and Injuries/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Causality , Comorbidity , Cross-Sectional Studies , Female , Humans , Length of Stay/statistics & numerical data , Male , Middle Aged , Midwestern United States/epidemiology , Needs Assessment , Odds Ratio , Registries , Substance-Related Disorders/complications , Substance-Related Disorders/metabolism , Tomography, X-Ray Computed , Trauma Centers , Violence/statistics & numerical data , Wounds and Injuries/complications
12.
Crit Care Med ; 33(2): 324-30, 2005 Feb.
Article in English | MEDLINE | ID: mdl-15699835

ABSTRACT

BACKGROUND AND AIMS: Elevated residual volumes (RV), considered a marker for the risk of aspiration, are used to regulate the delivery of enteral tube feeding. We designed this prospective study to validate such use. METHODS: Critically ill patients undergoing mechanical ventilation in the medical, coronary, or surgical intensive care units in a university-based tertiary care hospital, placed on intragastric enteral tube feeding through nasogastric or percutaneous endoscopic gastrostomy tubes, were included in this study. Patients were fed Probalance (Nestle USA) to provide 25 kcal/kg per day (to which 10 yellow microscopic beads and 4.5 mL of blue food coloring per 1,500 mL was added). Patients were randomized to one of two groups based on management of RV: cessation of enteral tube feeding for RV >400 mL in study patients or for RV >200 mL in controls. Acute Physiology and Chronic Health Evaluation (APACHE) III, bowel function score, and aspiration risk score were determined. Bedside evaluations were done every 4 hrs for 3 days to measure RV, to detect blue food coloring, to check patient position, and to collect secretions from the trachea and oropharynx. Aspiration/regurgitation events were defined by the detection of yellow color in tracheal/oropharyngeal samples by fluorometry. Analysis was done by analysis of variance, Spearman's correlation, Student's t-test, Tukey's method, and Cochran-Armitage test. RESULTS: Forty patients (mean age, 44.6 yrs; range, 18-88 yrs; 70% male; mean APACHE III score, 40.9 [range, 12-85]) were evaluated (21 on nasogastric, 19 on percutaneous endoscopic gastrostomy feeds) and entered into the study. Based on 1,118 samples (531 oral, 587 tracheal), the mean frequency of regurgitation per patient was 31.3% (range, 0% to 94%), with a mean RV for all regurgitation events of 35.1 mL (range, 0-700 mL). The mean frequency of aspiration per patient was 22.1% (range, 0% to 94%), with a mean RV for all aspiration events of 30.6 mL (range, 0-700 mL). The median RV for both regurgitation and aspiration events was 5 mL. Over a wide range of RV, increasing from 0 mL to >400 mL, the frequency of regurgitation and aspiration did not change appreciably. Aspiration risk and bowel function scores did not correlate with the incidence of aspiration or regurgitation. Blue food coloring was detected on only three of the 1,118 (0.27%) samples. RV was < or =50 mL on 84.1% and >400 mL on 1.4% of bedside evaluations. Sensitivities for detecting aspiration per designated RV were as follows: 400 mL = 1.5%; 300 mL = 2.3%; 200 mL = 3.0%; and 150 mL = 4.5%. Low RV did not assure the absence of events, because the frequency of aspiration was 23.0% when RV was <150 mL. Raising the designated RV for cessation of enteral tube feeding from 200 mL to 400 mL did not increase the risk, because the frequency of aspiration was no different between controls (21.6%) and study patients (22.6%). The frequency of regurgitation was significantly less for patients with percutaneous endoscopic gastrostomy tubes compared with those with nasogastric tubes (20.3% vs. 40.7%, respectively; p = .046). There was no correlation between the incidence of pneumonia and the frequency of regurgitation or aspiration. CONCLUSIONS: Blue food coloring should not be used as a clinical monitor. Converting nasogastric tubes to percutaneous endoscopic gastrostomy tubes may be a successful strategy to reduce the risk of aspiration. No appropriate designated RV level to identify aspiration could be derived as a result of poor sensitivity over a wide range of RV. Study results do not support the conventional use of RV as a marker for the risk of aspiration.


Subject(s)
Critical Illness , Enteral Nutrition , Gastric Emptying , Gastroesophageal Reflux/diagnosis , Inhalation , APACHE , Adolescent , Adult , Aged , Aged, 80 and over , Coloring Agents , Enteral Nutrition/adverse effects , Female , Gastroesophageal Reflux/etiology , Gastrostomy , Humans , Intensive Care Units , Intestines/physiopathology , Intubation, Gastrointestinal , Male , Middle Aged , Pneumonia, Aspiration/diagnosis , Pneumonia, Aspiration/etiology , Pneumonia, Aspiration/physiopathology , Respiration, Artificial , Risk Factors , Sensitivity and Specificity
13.
Am Surg ; 70(6): 522-5, 2004 Jun.
Article in English | MEDLINE | ID: mdl-15212407

ABSTRACT

Laryngotracheal injuries are potentially lethal injuries whose diagnosis can be difficult. The purpose of this study was to delineate the effect of injury mechanism on the types of injury sustained and patient outcome. Patient records during a 7-year period were reviewed for injury mechanism, patient demographics, clinical presentation, patient evaluation, injury location, associated injuries, operative interventions, and outcome. Fifteen patients with laryngotracheal injuries were studied. Blunt injuries were more common (60%). Patient demographics, mortality, average length of stay, and Injury Severity Score were similar for both groups. Prevalent physical findings on examination included subcutaneous air (53%), hoarseness (47%), stridor (20%), and neck tenderness (27%). Diagnosis was confirmed by CT scan of the neck (66% blunt, 33% penetrating) or bronchoscopy (44% blunt, 66% penetrating). Injury location, patient disposition, and associated injures were the same for both groups. The most frequent operative intervention performed for both groups consisted of a primary airway repair via a collar incision within 8 hours of injury. Only patients with a laryngeal injury required concomitant tracheostomy regardless of mechanism. Blunt and penetrating neck injuries resulted in similar types of tracheal and laryngeal injuries. Anatomic location of the injury determined the need for tracheostomy. Regardless of mechanism, the overall outcome for patients with laryngotracheal injuries is good when injuries are recognized and treated expeditiously. A high level of suspicion must be maintained when evaluating all potential laryngotracheal injury patients irrespective of the mechanism of injury.


Subject(s)
Larynx/injuries , Trachea/injuries , Wounds and Injuries/etiology , Adult , Female , Humans , Injury Severity Score , Kentucky/epidemiology , Length of Stay/statistics & numerical data , Male , Tracheostomy , Treatment Outcome , Wounds and Injuries/diagnosis , Wounds and Injuries/epidemiology , Wounds and Injuries/therapy
14.
Am J Surg ; 187(3): 332-7, 2004 Mar.
Article in English | MEDLINE | ID: mdl-15006560

ABSTRACT

BACKGROUND: The purpose of this study was to describe the admission characteristics of trauma victims that are predictive of the development of delirium during hospitalization. METHODS: In this case-control study, data (demographics, injury type, medical histories, admission laboratory values, medications, and outcomes) were obtained from the records of 120 patients in whom delirium developed and 145 in whom it did not after admission for traumatic injury. Odds ratios were employed to identify significant predictors used in a stepwise logistic regression analysis. RESULTS: Admission characteristics, retained after stepwise logistic regression, that were independently predictive of delirium were age more than 45 years, positive admission blood alcohol, and an elevated mean corpuscular volume. Those in whom delirium developed had longer hospital and intensive care unit lengths of stay than in whom it did not. CONCLUSIONS: Older patients and alcoholics are at increased risk for delirum. Therapies directed at prevention have the potential to improve care and decrease lengths of stay.


Subject(s)
Delirium/epidemiology , Multiple Trauma/therapy , Patient Admission/standards , Age Distribution , Case-Control Studies , Critical Care , Delirium/diagnosis , Female , Hospitalization , Humans , Incidence , Injury Severity Score , Logistic Models , Male , Multiple Trauma/diagnosis , Multiple Trauma/mortality , Odds Ratio , Patient Admission/trends , Predictive Value of Tests , Probability , Prognosis , Risk Assessment , Sex Distribution , Survival Rate , Time Factors , Trauma Centers
15.
J Trauma ; 53(5): 901-6, 2002 Nov.
Article in English | MEDLINE | ID: mdl-12435941

ABSTRACT

BACKGROUND: The development of delirium tremens (DT) is associated with significant morbidity and mortality. This study identifies characteristics in trauma patients that are predictive of DT. METHODS: Data from 1,856 trauma patients who either developed DT (n = 105) or had a positive blood alcohol concentration but did not develop DT (n = 1,751) were collected from the trauma registry of a Level I trauma center. Odds ratios were used to measure the association between predictors and DT as an outcome and between DT and length of stay as an outcome. RESULTS: Of seven significant (p < 0.05) predictors of DT, four were retained after stepwise logistic regression: age >40, white race, burn as a mechanism of injury and, as a negative predictor, motor vehicle collision as a mechanism of injury. The DT group stayed an average of 6.5 and 5.2 days longer in the hospital and the intensive care unit, respectively, than those in the control group. CONCLUSION: It is possible to determine which intoxicated trauma patients are at increased risk for DT using the above predictors. Patients who develop DT have worse outcomes than those who do not. Whether routine DT prophylaxis would improve outcomes among those at increased risk for DT is unknown, but deserves further study.


Subject(s)
Alcohol Withdrawal Delirium/etiology , Multiple Trauma , Adult , Aged , Alcohol Withdrawal Delirium/diagnosis , Female , Humans , Logistic Models , Male , Middle Aged , Odds Ratio , Predictive Value of Tests , Registries , Retrospective Studies , Risk Factors , Trauma Centers
16.
Surgery ; 132(4): 642-6; discussion 646-7, 2002 Oct.
Article in English | MEDLINE | ID: mdl-12407348

ABSTRACT

BACKGROUND: Current evaluation of patients with negative findings on a focused abdominal sonography for trauma scan and an isolated increase of admission hepatic enzymes includes abdominal computed tomography (CT). Many of these patients do not have clinically important hepatic injuries. The purpose of this study was to establish the admission aspartate aminotransferase (AST) level below which patients do not need an abdominal CT for injury evaluation and treatment. METHODS: Patients who were hemodynamically stable, had a focused abdominal sonography for trauma scan with negative findings, and an AST level greater than 200 IU/L were identified over a 1-year period. Medical records were reviewed for demographics, injuries sustained, mechanism, evaluation, interventions, and complications. RESULTS: A total of 67 patients, mostly with blunt trauma, were identified; 42 (63%) had an AST level < 360 IU/L, and 25 (37%) had an AST level > 360 IU/L. Patients with an AST level > 360 IU/L had a 88% chance of having any hepatic injury and a 44% chance of having an injury of grade III or greater (P =.0001). Patients with an AST level of < 360 IU/L only had a 14% chance of having a liver injury and no chance of having an injury of grade III or greater (P =.036). CONCLUSIONS: Clinically important hepatic injuries are not missed if an abdominal CT is only performed for patients with a focused abdominal sonography for trauma scan with negative findings and an AST level of > 360 IU/L. Eliminating unnecessary CT allows for more cost-effective use of resources.


Subject(s)
Abdominal Injuries/diagnostic imaging , Abdominal Injuries/surgery , Aspartate Aminotransferases/blood , Abdominal Injuries/blood , Abdominal Injuries/enzymology , Abdominal Injuries/mortality , Adult , Biomarkers/blood , Female , Hemodynamics , Humans , Liver/injuries , Male , Tomography, X-Ray Computed , Treatment Outcome , Ultrasonography , Wounds, Nonpenetrating/blood , Wounds, Nonpenetrating/diagnostic imaging , Wounds, Nonpenetrating/surgery
17.
J Trauma ; 53(4): 635-8; discussion 638, 2002 Oct.
Article in English | MEDLINE | ID: mdl-12394859

ABSTRACT

BACKGROUND: Little controversy surrounds the treatment of hemodynamically unstable patients with transmediastinal gunshot wounds (TMGSWs). These patients generally have cardiac or major vascular injuries and require immediate operation. In hemodynamically stable patients, debate surrounds the extent and order of the diagnostic evaluation. These patients can be uninjured, or can have occult vascular, esophageal, or tracheobronchial injuries. Evaluation has traditionally often included angiography, bronchoscopy, esophagoscopy, esophagography, and pericardial evaluation (i.e., pericardial window) for all hemodynamically stable patients with TMGSWs. Expansion of the use of computed tomographic (CT) scanning in penetrating injury led to a modification of our protocol. Currently, our TMGSW evaluation algorithm for stable patients consists of chest radiograph, focused abdominal sonography for trauma, and contrast-enhanced helical CT scan of the chest with directed further evaluation. The purpose of this study is to evaluate the efficiency of contrast-enhanced helical CT scan for evaluating potential mediastinal injuries and to determine whether patients can be simply observed or require further investigational studies. METHODS: Medical records of hemodynamically stable patients admitted with TMGSWs over a 2-year period were reviewed for demographics, mechanism of injury, method of evaluation, operative interventions, injuries, length of stay, and complications. CT scans were considered positive if they contained a mediastinal hematoma or pneumomediastinum, or demonstrated proximity of the missile track to major mediastinal structures. RESULTS: Twenty-two stable patients were studied. CT scans were positive in seven patients. Directed further diagnostic evaluation in those seven patients revealed two patients who required operative intervention. Sixty-eight percent of patients had negative CT scans and were observed in a monitored setting without further evaluation. There were no missed injuries. The hospital charges generated with the CT scan-based protocol are significantly less than with the standard evaluation. CONCLUSION: Contrast-enhanced helical CT scanning is a safe, efficient, and cost-effective diagnostic tool for evaluating hemodynamically stable patients with mediastinal gunshot wounds. Positive CT scan results direct the further evaluation of potentially injured structures. Patients with negative results can safely be observed in a monitored setting without further evaluation.


Subject(s)
Mediastinum/injuries , Thoracic Injuries/diagnostic imaging , Wounds, Gunshot/diagnostic imaging , Adolescent , Adult , Contrast Media , Cost-Benefit Analysis , Costs and Cost Analysis , Humans , Mediastinum/diagnostic imaging , Mediastinum/surgery , Middle Aged , Radiography, Thoracic/economics , Thoracic Injuries/economics , Thoracic Injuries/surgery , Tomography, X-Ray Computed/economics , Wounds, Gunshot/economics , Wounds, Gunshot/surgery
18.
J Clin Gastroenterol ; 35(3): 209-13, 2002 Sep.
Article in English | MEDLINE | ID: mdl-12192194

ABSTRACT

Acquisition of enteral access and provision of a sufficient volume of enteral nutrients early in the hospital course of a critically ill patient afford an opportunity to improve the outcome of that patient through the progression of his or her disease process. Failure to use the enteral route of feeding not only squanders this opportunity, but may, in addition, promote a pro-inflammatory state, which exacerbates disease severity and worsens morbidity. Enteral feeding provides a conduit for the delivery of immune stimulants and serves as effective prophylaxis against stress-induced gastropathy and gastrointestinal hemorrhage. Tube placement beyond the stomach into the small bowel in hypermetabolic, severely ill patients prone to ileus and disordered gut motility aids delivery of enteral nutrients while reducing risk of aspiration. Endoscopic skills and expertise in gastrointestinal physiology are vital to the success of a nutrition support service and the provision of enteral tube feeding.


Subject(s)
Critical Illness , Enteral Nutrition , Burns/physiopathology , Burns/therapy , Endoscopy, Digestive System , Humans , Intubation, Intratracheal
19.
Arch Surg ; 137(6): 718-22; discussion 722-3, 2002 Jun.
Article in English | MEDLINE | ID: mdl-12049544

ABSTRACT

HYPOTHESIS: Focused abdominal sonography for trauma (FAST) is an unreliable method for assessing intra-abdominal injury in patients with seat belt marks. DESIGN: Retrospective review of trauma patients with intestinal injury and seat belt marks during a 3-year period. Records were reviewed for patient demographics, FAST results, computed tomographic (CT) scan results, and operative findings. The CT scan results were considered positive if bowel wall thickening, extraluminal air, or free fluid without solid organ injury were present. SETTING: University hospital designated as a level I trauma center. PATIENTS: Twenty-three patients who required operation for intestinal or mesenteric injury and who had an abdominal seat belt mark. MAIN OUTCOME MEASURE: Sensitivity of FAST in these patients. RESULTS: All patients were evaluated using both FAST and CT scan of the abdomen and pelvis. Eighteen patients (78%) had either negative or equivocal FAST results when significant intestinal injury was present. All 23 patients had CT scan findings suggestive of bowel or mesenteric injury. Moderate-to-large free intraperitoneal fluid without solid organ injury was the most common finding (n = 21, 91%). Operative findings included small-bowel perforation (n = 18, 78%), colonic perforation (n = 7, 30%), bowel deserosalization (n = 8, 35%), and isolated mesenteric injury (n = 5, 22%). Sixteen patients (70%) had multiple intra-abdominal injuries. All patients were taken directly from the emergency department to the operating room. Seventeen percent of operative explorations (4/23) were nontherapeutic (no repairs required). CONCLUSION: This study confirms that FAST cannot reliably exclude intestinal injury in patients with seat belt marks.


Subject(s)
Abdomen/diagnostic imaging , Intestinal Perforation/diagnostic imaging , Intestines/injuries , Seat Belts/adverse effects , Wounds, Nonpenetrating/diagnostic imaging , Accidents, Traffic , Adolescent , Adult , Humans , Intestinal Perforation/etiology , Middle Aged , Radiography, Abdominal , Retrospective Studies , Sensitivity and Specificity , Tomography, X-Ray Computed , Ultrasonography , Wounds, Nonpenetrating/etiology
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