[Laser irradiation: study of general and local mechanisms of its action in irradiation of the eyeball. An experimental study. 3]. / Lazernoe izluchenie: issledovanie obshchego i mestnogo mekhanizma deistviia pri obluchenii glaznogo iabloka. Eksperimental'noe issledovanie. Soobshchenie 3.

Rabbit ocular tissues, brain, and blood were examined before and after irradiation of the eyeball with He-Ne laser. Scanning electron microscopy, radioimmunoassay, and biochemical methods were employed in the study. The findings evidence that irradiation of the eyeball results in reduced lipid peroxidation activity and elevated antiradical defense enzymes activity not only in ocular tissues but in the corresponding brain hemisphere and blood, which fact appears to be due to direct effect of laser radiation on the blood and brain via the optic nerve that may be a light conductor for a certain wavelength. Local increase of the eyeball corneal permeability in laser irradiation may be explained by activation of membrane phospholipases, combined with electrolyte shifts; morphologically and functionally it manifests by changed endotheliocyte stereotopography.

[The effect of dexamethasone on the metabolism of the hormone regulators of carbohydrate metabolism in the postresuscitation period]. / Vliianie deksametazona na obmen gormonov--reguliatorov metabolizma uglevodov v postreanimatsionnom periode.

Administration of dexamethasone (dexasone) to dogs against the background of dysfunction of the hypothalamic-pituitary-adrenal system (HPAS) developing in the first three days of the postresuscitation period causes diverse changes in secretion of hormones of the pancreas. At a relative normalization of HPAS functioning noted 7 days after resuscitation the drug was shown to decrease intensity of glycolysis and processes of lipid peroxidation.

[Impairment of glutathione metabolism in the liver of resuscitated rats and its correction]. / Narushenie obmena gliutationa v pecheni reanimirovannykh krys i ego korrektsiia.

Elevated synthesis of glutathione in liver tissue of rats after resuscitation did not exclude its deficiency in the animals. Administration of exogenous glutathione before asphyxia decreased the rate of structural membrane lipids peroxidation as well as contributed to more effective function of energy generation systems.

[Comparative characteristics of methods of evaluation of plasma toxicity and severity of toxemia in acute diffuse peritonitis]. / Sravnitel'naia kharakteristika metodov otsenki toksichnosti plazmy krovi i tiazhesti intoksikatsii pri ostrom razlitom peritonite.

Experimental and clinical investigations have established the method of biological testing on mice and the leukocyte index of intoxication to be objective and reliable criteria for the estimation of the blood plasma toxicity and the degree of intoxication.

[Possible mechanisms of rat liver peroxidation of lipids in the recovery period after mechanical asphyxia]. / O vomozhnykh mekhanizmakh perekisnogo okisleniia lipidov pecheni krys v vosstanovitel'nom periode posle mekhanicheskoi asfiksii.

Lipid peroxidation was stimulated in rat liver tissue after mechanical asphyxia due to inhibition of the antiradical and antiperoxidase systems simultaneously with an apparent increase in production of free radicals. Lipid peroxidation in liver membranes was maintained at the high level after reanimation despite of normalization (and occasional increase) of the activities of superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase.