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Small ; 9(18): 3051-7, 2013 Sep 23.
Article in English | MEDLINE | ID: mdl-23606461

ABSTRACT

On-demand degradable polymer particles are fabricated via electrospraying of a solution of acetal-protected dextran that further includes 2-(4-methoxystyryl)-4,6-bis(trichloromethyl)-1,3,5-triazine as a photoacid generator. The illumination of UV light gives rise to photoacid and activates the catalytic deprotection of hydroxyl groups of dextran, leading to controlled dissolution of the microparticles in water.


Subject(s)
Drug Carriers/chemistry , Drug Delivery Systems/methods , Polymers/chemistry , Nanoparticles/chemistry
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