ABSTRACT
A clinical analysis of 37 cases of twin pregnancy complicated by eclampsia showed that: (1) the incidence of twins in the total 1,030 cases of eclampsia was three times the figure in the general population, (2) the maternal mortality was slightly higher and perinatal mortality slightly lower than in unselected eclamptic patients, (3) patients with postpartum eclampsia showed significant differences in comparison with antepartum and intrapartum cases, (4) perinatal and maternal mortality were lower in cases delivered by cesarean section, (5) perinatal mortality was significantly higher in male fetuses, and (6) five of the six maternal deaths occurred in cases of male twins. In addition, the data suggest the presence of a reciprocal negative influence between maternal eclampsia and male twins and that this type of eclampsia may be the best example of essential preeclampsia.
Subject(s)
Eclampsia/mortality , Pregnancy Complications/mortality , Pregnancy, Multiple , Adult , Cesarean Section/mortality , Eclampsia/etiology , Female , Humans , Incidence , Infant Mortality , Maternal Mortality , Pregnancy , Pregnancy Complications/etiology , Risk Factors , Sex Factors , TwinsABSTRACT
Human chorionic gonadotropin beta subunit (beta-HCG) was measured in amniotic fluid and radioimmunoassay levels compared with those obtained in plasma from normal pregnant women. Amniotic beta-HCG exhibited a secretory pattern similar to that seen in the plasma compartment. Nonetheless amniotic beta-HCG had an elevation peak later than its plasma counterpart, with a progressive decrease that persisted throughout gestation without reaching a nadir as it occurred in plasma. Such a pattern of HCG production contained in the amnion is compatible with an HCG conformation released by the syncytiotrophoblast.
Subject(s)
Amniotic Fluid/analysis , Chorionic Gonadotropin/analysis , Peptide Fragments/analysis , Chorionic Gonadotropin/blood , Chorionic Gonadotropin, beta Subunit, Human , Female , Gestational Age , Humans , Peptide Fragments/blood , Pregnancy , Radioimmunoassay , Trophoblasts/metabolismSubject(s)
Breech Presentation , Labor Presentation , Obstetric Labor Complications/therapy , Female , Humans , PregnancyABSTRACT
En recien nacidos de madres con purpura trombocitopenica idiopatica se puede presentar purpura neonatal como resultado del paso de anticuerpos antiplaquetarios a traves de la placenta; la principal complicacion puede ser la hemorragia intracraneana. Los metodos que se han propuesto para evitar o prevenir esta complicacion no han mostrado ser utiles en estudios amplios. En 32 pacientes embarazadas con purpura trombocitopenica idiopatica se administro prednisona a dosis bajas una a dos semanas antes y durante el parto.Otras 14 pacientes no recibieron corticoesteroides. En los recien nacidos cuyas madres recibieron prednisona la mediana de la cuenta de plaquetas, inmediatamente despues del parto, fue de 181 x 10 elevado 9 x 1; em cambio, en el grupo que no recibio corticoesteroides, fue de 108 x 10 elevado 9 x 1; (p, < 0.001). Ademas en solo el 21% de los recien nacidos cuyas madres recibieron esteroides se presento purpura en comparacion con el 66% de quienes no lo recibieron
