ABSTRACT
OBJECTIVES: We aimed to compare outcomes of patients with middle cerebral artery (MCA) aneurysms treated by either microsurgical clipping or endovascular therapy and provide a treatment algorithm based on available evidence. MATERIALS AND METHODS: We performed a retrospective analysis of 77 patients with 95 MCA aneurysms. Demographic, clinical, and aneurysm morphological variables were collected. Patients were divided into two groups depending on the received treatment. Clinical and radiological outcomes were collected at the end of a 1-year follow-up period and compared between both treatment groups. RESULTS: Mean age was 51.4 years. Fifty patients (65%) underwent microsurgical clipping and 27 (35%) were treated by endovascular therapy. Fifty-four patients (70%) presented with subarachnoid hemorrhage, while 23 (30%) were treated for unruptured aneurysms. Patients with subarachnoid hemorrhage were more frequently treated by microsurgical clipping than patients with unruptured aneurysms. Clinical outcomes, including functional status, were similar between treatment groups after 1-year follow-up even when adjusting for clinical presentation. Residual aneurysms were found less frequently in the microsurgical group (OR = 0.09; p < 0.001). CONCLUSIONS: In patients with MCA aneurysms, clinical outcomes at 1 year are similar between microsurgical clipping and endovascular therapy. However, microsurgery is associated with a lower risk of residual aneurysms.
OBJETIVO: Evaluar y comparar desenlaces de pacientes con aneurismas de arteria cerebral media (ACM) tratados mediante clipaje microquirúrgico o terapia endovascular, y proponer un algoritmo de tratamiento basado en evidencia. MATERIAL Y MÉTODOS: Estudio retrospectivo de 77 pacientes con 95 aneurismas de ACM. Se recabaron variables demográficas, clínicas y morfológicas de los aneurismas tratados. Se dividieron a los pacientes en dos grupos dependiendo del tratamiento recibido y se compararon los desenlaces clínicos y radiológicos al final del seguimiento a un año entre ambos grupos. RESULTADOS: La edad promedio fue 51.4 años. 50 pacientes (65%) fueron sometidos a clipaje microquirúrgico y 27 (35%) a terapia endovascular. 54 pacientes (70%) presentaron hemorragia subaracnoidea, quienes fueron tratados mediante microcirugía en mayor proporción que aquellos con aneurismas no rotos. Los desenlaces clínicos, incluyendo el estado funcional, fueron similares entre ambos grupos al año de seguimiento, aún tras ajustar el análisis por presentación clínica. El grupo de microcirugía presentó una menor proporción de aneurismas residuales (OR = 0.09; p < 0.001). CONCLUSIONES: En pacientes con aneurismas de ACM, los desenlaces clínicos a un año son similares entre clipaje microquirúrgico y terapia endovascular. Sin embargo, la microcirugía se asocia a un menor riesgo de aneurismas residuales.
