[The antidiphtheria and antitetanus immunities of children of the Maritime Territory after the use of adsorbed DTP vaccine and adsorbed DT-m anatoxin]. / Sostoianie protivodifteriinogo i protivostolbniachnogo immuniteta detei Primorskogo kraia pri ispol'zovanii AKDS-vaktsiny i ADS-M-anatoksina.

The state of collective immunity to diphtheria and tetanus in children of preschool age, depending on the kind of vaccine preparation used for immunization, was studied. The immunological potency of adsorbed DPT vaccine (i.e. its capacity of forming prolonged and stable basic immunity) was shown to be higher in comparison with the potency of adsorbed DT toxoid with reduced antigen content (DT-R). The study revealed that in all groups of children the level of antitetanus immunity was higher than the level of antidiphtheria immunity, and 3 years later its decrease was less pronounced. A stricter approach to giving medical grounds for the use of low-reactive adsorbed DT-R in the immunization of children belonging to groups of risk is recommended.

[Diphtheria in the Maritime Territory]. / Difteriia v Primorskom krae.

The results of the analysis of the present epidemiological situation in diphtheria in the Maritime Territory are presented. The data on absolute and intensive characteristics, death rate due to this infection, the vaccination status of diphtheria patients, as well as the results of the study of the level and intensity of antidiphtheria immunity in the healthy population of the territory. The study revealed that the defects of collective antidiphtheria immunity correlated with morbidity rate among adults and children. Adults aged 40-50 years and children aged 6-7 years were regarded as risk groups; among them the highest proportion of nonimmune persons and the highest diphtheria morbidity rate were registered. Stabilization achieved by the present moment was the result of the mass immunization of the adult population, ensuring the necessary coverage (92%) of vaccination in 1995.

[Collective immunity to diphtheria in the children and adolescents of Vladivostok during a mass immunization against this infection]. / Kollektivnyi immunitet k difterii u detei i podrostkov Vladivostoka v period massovoi immunizatsii protiv étoi infektsii.

The state of collective immunity to diphtheria in children and adolescents of Vladivostok was studied. Adsorbed DPT vaccine was shown to have higher immunological effectiveness in comparison with adsorbed DT toxoid with reduced antigen content. As revealed in this study, as early as in 2 years a part of the children lost their immunity, irrespective of the preparation used for vaccination, and enlarged the reserve of initially seronegative children and adolescents, capable of maintaining the epidemic process of diphtheria.