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1.
Radiol Med ; 128(6): 726-733, 2023 Jun.
Article in English | MEDLINE | ID: mdl-37233906

ABSTRACT

Computer-aided diagnosis of chest X-ray (CXR) images can help reduce the huge workload of radiologists and avoid the inter-observer variability in large-scale early disease screening. Recently, most state-of-the-art studies employ deep learning techniques to address this problem through multi-label classification. However, existing methods still suffer from low classification accuracy and poor interpretability for each diagnostic task. This study aims to propose a novel transformer-based deep learning model for automated CXR diagnosis with high performance and reliable interpretability. We introduce a novel transformer architecture into this problem and utilize the unique query structure of transformer to capture the global and local information of the images and the correlation between labels. In addition, we propose a new loss function to help the model find correlations between the labels in CXR images. To achieve accurate and reliable interpretability, we generate heatmaps using the proposed transformer model and compare with the true pathogenic regions labeled by the physicians. The proposed model achieves a mean AUC of 0.831 on chest X-ray 14 and 0.875 on PadChest dataset, which outperforms existing state-of-the-art methods. The attention heatmaps show that our model could focus on the exact corresponding areas of related truly labeled pathogenic regions. The proposed model effectively improves the performance of CXR multi-label classification and the interpretability of label correlations, thus providing new evidence and methods for automated clinical diagnosis.


Subject(s)
Diagnosis, Computer-Assisted , Radiologists , Humans , X-Rays , Radiography , Thorax
2.
IEEE Trans Pattern Anal Mach Intell ; 45(5): 6183-6195, 2023 May.
Article in English | MEDLINE | ID: mdl-36067105

ABSTRACT

3D point cloud registration is a fundamental problem in computer vision and robotics. Recently, learning-based point cloud registration methods have made great progress. However, these methods are sensitive to outliers, which lead to more incorrect correspondences. In this paper, we propose a novel deep graph matching-based framework for point cloud registration. Specifically, we first transform point clouds into graphs and extract deep features for each point. Then, we develop a module based on deep graph matching to calculate a soft correspondence matrix. By using graph matching, not only the local geometry of each point but also its structure and topology in a larger range are considered in establishing correspondences, so that more correct correspondences are found. We train the network with a loss directly defined on the correspondences, and in the test stage the soft correspondences are transformed into hard one-to-one correspondences so that registration can be performed by a correspondence-based solver. Furthermore, we introduce a transformer-based method to generate edges for graph construction, which further improves the quality of the correspondences. Extensive experiments on object-level and scene-level benchmark datasets show that the proposed method achieves state-of-the-art performance.

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