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1.
Sensors (Basel) ; 20(17)2020 Aug 19.
Article in English | MEDLINE | ID: mdl-32825008

ABSTRACT

To monitor road safety, billions of records can be generated by Controller Area Network bus each day on public transportation. Automation to determine whether certain driving behaviour of drivers on public transportation can be considered safe on the road using artificial intelligence or machine learning techniques for big data analytics has become a possibility recently. Due to the high false classification rates of the current methods, our goal is to build a practical and accurate method for road safety predictions that automatically determine if the driving behaviour is safe on public transportation. In this paper, our main contributions include (1) a novel feature extraction method because of the lack of informative features in raw CAN bus data, (2) a novel boosting method for driving behaviour classification (safe or unsafe) to combine advantages of deep learning and shallow learning methods with much improved performance, and (3) an evaluation of our method using a real-world data to provide accurate labels from domain experts in the public transportation industry for the first time. The experiments show that the proposed boosting method with our proposed features outperforms seven other popular methods on the real-world dataset by 5.9% and 5.5%.


Subject(s)
Artificial Intelligence , Automobile Driving , Automation , Machine Learning , Transportation
2.
Pharmacol Res ; 160: 105037, 2020 10.
Article in English | MEDLINE | ID: mdl-32590103

ABSTRACT

In personalized medicine, many factors influence the choice of compounds. Hence, the selection of suitable medicine for patients with non-small-cell lung cancer (NSCLC) is expensive. To shorten the decision-making process for compounds, we propose a computationally efficient and cost-effective collaborative filtering method with ensemble learning. The ensemble learning is used to handle small-sample sizes in drug response datasets as the typical number of patients in a cancer dataset is very small. Moreover, the proposed method can be used to identify the most suitable compounds for patients without genetic data. To the best of our knowledge, this is the first method to provide effective recommendations without genetic data. We also constructed a reliable dataset that includes eight NSCLC cell lines and ten compounds that have been approved by the Food and Drug Administration. With the new dataset, the experimental results demonstrated that the dataset shift phenomenon that commonly occurs in practical biomedical data does not occur in this problem. The experimental results demonstrated that our proposed method can outperform two state-of-the-art recommender system techniques on both the NCI60 dataset and our new dataset. Our model can be applied to the prediction of drug sensitivity with less labor-intensive experiments in the future.


Subject(s)
Antineoplastic Agents/therapeutic use , Artificial Intelligence , Lung Neoplasms/drug therapy , Precision Medicine/methods , Algorithms , Animals , Apoptosis/drug effects , Carcinoma, Non-Small-Cell Lung , Cell Line, Tumor , Cell Movement/drug effects , Clinical Decision-Making , Computer Simulation , Cost-Benefit Analysis , Databases, Factual , Humans
3.
J Colloid Interface Sci ; 513: 389-399, 2018 Mar 01.
Article in English | MEDLINE | ID: mdl-29172118

ABSTRACT

Two-dimensional transition metal dichalcogenides (2D TMDs) and their heterostructures have by far stimulated growing research interests in the field of optoelectronics and photocatalysis. In this regard, scalable fabrication of 2D TMDs at an environmentally-benign and cost-effective manner via liquid phase exfoliation is a particularly fascinating concept. Herein we report a facile and green strategy to produce few-layered WS2 suspensions at a large scale by a direct exfoliation of commercial WS2 powders in water-ethanol mixtures. In turn, by making full use of the features of 2D layered WS2, a novel 2D WS2/MoS2 composite was constructed for the first time via an in-situ hydrothermal reaction to grow MoS2 nanoflakes onto few-layered WS2 basal planes. The as-obtained WS2/MoS2 heterostructure was investigated for photocatalytic applications. Such a hybrid material demonstrated superior photocatalytic activity in the photocatalysis of organic dye molecules relative to that of pristine 2D WS2, MoS2 and their physical mixtures. This enhancement was associated with the 2D WS2/MoS2 heterostructuring effect. In addition, comparisons of the photocatalytic performances of our heterojunctions with those of recently reported 2D TMD-based hybrid materials manifested a significantly higher efficiency.

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