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1.
Biomed Khim ; 50(1): 57-63, 2004.
Article in Russian | MEDLINE | ID: mdl-15108627

ABSTRACT

The state of enzymatic and nonenzymatic components of antioxidant system and also lipid peroxidation processes were studied in brain of rats with toxic pulmonary edema induced by inhalation of nitric oxides. The changes in the state of antioxidant system components in brain accompanied the development of toxic pulmonary edema. The main changes were found in nonenzymatic components of the antioxidant system, particularly in thiol and disulfide groups. Lipid peroxidation processes were not activated during the toxic pulmonary edema.


Subject(s)
Antioxidants/metabolism , Brain/metabolism , Pulmonary Edema/metabolism , Administration, Inhalation , Animals , Lipid Peroxidation , Male , Nitrogen Oxides , Poisoning/metabolism , Pulmonary Edema/chemically induced , Rats
2.
Vopr Med Khim ; 46(6): 564-73, 2000.
Article in Russian | MEDLINE | ID: mdl-11234280

ABSTRACT

The state of enzymatic and non-enzymatic components of antioxidant system and also lipid peroxidation processes in blood and lungs of rats with toxic pulmonary edema induced by inhalation of nitric oxides were investigated. The changes in the state of blood and lung antioxidant system components accompany the development of toxic pulmonary edema and coincide in time-course of edema manifestation. The determined changes were more pronounced in blood than in lungs.


Subject(s)
Antioxidants/metabolism , Lung/metabolism , Pulmonary Edema/physiopathology , Animals , Lipid Peroxidation , Male , Nitric Oxide/metabolism , Pulmonary Edema/blood , Pulmonary Edema/chemically induced , Pulmonary Edema/metabolism , Rats
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