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1.
Anesth Analg ; 2023 Dec 08.
Article in English | MEDLINE | ID: mdl-38091501

ABSTRACT

BACKGROUND: The intraoperative autonomic neural blockade (ANB) was found safe and effective in controlling pain and associated symptoms and reducing analgesic consumption after laparoscopic sleeve gastrectomy (LSG). This study evaluated whether ANB performed at the outset of LSG reduces anesthetic consumption and promotes hemodynamic stability. METHODS: This prospective, double-blinded, randomized trial involved patients undergoing LSG in 2 high-volume institutions. Patients were randomized to receive ANB either at the onset or the end of the procedure. The primary outcome measure was the consumption of remifentanil and sevoflurane. Secondary outcomes included Aldrete scale score differences in the recovery room and hemodynamic stability during the surgery. RESULTS: In total, 80 patients (40 in the ANB at the onset group and 40 in the control group) were included for analysis. The consumption of remifentanil was significantly lower in the onset group compared to the control group (mean difference -0.04 mcg/kg/min, 95% confidence interval [CI], -0.06 to -0.02; P < .0001). There were no differences in the Aldrete scale scores between the 2 groups. Mean heart rate (HR) and mean arterial pressure (MAP) were also significantly less during surgery in the ANB at the onset group. No complications related to the ANB occurred. CONCLUSIONS: Performing ANB at the onset of LSG is a safe and effective approach that reduces remifentanil consumption and promotes hemodynamic stability during the procedure. This technique holds promise for optimizing anesthesia management in LSG and other minimally invasive surgeries.

2.
Obes Surg ; 32(11): 3551-3560, 2022 11.
Article in English | MEDLINE | ID: mdl-36050617

ABSTRACT

BACKGROUND: Visceral pain (VP) following laparoscopic sleeve gastrectomy remains a substantial problem. VP is associated with autonomic symptoms, especially nausea and vomiting, and is unresponsive to traditional pain management algorithms aimed at alleviating somatic (incisional) pain. The present study was performed to evaluate the safety and effectiveness of laparoscopic paragastric autonomic neural blockade (PG-ANB) in managing the symptoms associated with VP following sleeve gastrectomy. STUDY DESIGN: This prospective, double-blinded, randomized clinical trial involved patients undergoing laparoscopic sleeve gastrectomy at two high-volume institutions. The patients were randomized to laparoscopic transversus abdominis plane block with or without PG-ANB. The primary outcome was patient-reported pain scores assessed at 1, 8, and 24 h postoperatively. The secondary outcome measures were analgesic requirements, nausea, vomiting, hiccups, and hemodynamic changes immediately after PG-ANB and postoperatively. RESULTS: In total, 145 patients (block group, n = 72; control group, n = 73) were included in the study. The heart rate and mean arterial pressure significantly decreased 10 min after PG-ANB. The visual analog scale score for pain was significantly lower in the PG-ANB than in the control group at 1 h postoperatively (p < 0.001) and 8 h postoperatively (p < 0.001). Vomiting, nausea, sialorrhea, and hiccups were significantly less prevalent in the PG-ANB group. Patients in the PG-ANB group received fewer cumulative doses of analgesics at 1 h postoperatively (p = 0.003) and 8 h postoperatively (p < 0.001). No differences between the groups were detected at 24 h (p = 0.298). No complications related to PG-ANB occurred. CONCLUSION: PG-ANB safely and effectively reduces early VP, associated autonomic symptoms, and analgesic requirements after laparoscopic sleeve gastrectomy.


Subject(s)
Hiccup , Laparoscopy , Obesity, Morbid , Visceral Pain , Humans , Pain, Postoperative/drug therapy , Pain, Postoperative/prevention & control , Pain, Postoperative/etiology , Abdominal Muscles , Visceral Pain/complications , Visceral Pain/surgery , Prospective Studies , Hiccup/complications , Hiccup/surgery , Obesity, Morbid/surgery , Double-Blind Method , Gastrectomy/adverse effects , Laparoscopy/adverse effects , Analgesics , Vomiting/etiology , Nausea/etiology , Analgesics, Opioid , Anesthetics, Local
3.
Rev. méd. Caja Seguro Soc ; 18(1): 82-4, ene. 1986. ilus
Article in Spanish | LILACS | ID: lil-38178

ABSTRACT

La complicación más frecuente que se presenta en el traqueostoma después de la laringectomía total es la estenosis. Presentamos una técnica quirúrgica para la construcción del traqueostoma durante la laringectomía que en más de 50 operaciones nos ha dado buenos resultados con mínima incidencia de estenosis. Se discute el problema de la estenosis del traqueostoma y se consideran los factores etiológicos más importantes. Se revisan algunos principios para prevenir la estenosis y se describen varias técnicas para su corrección. La técnica hace énfasis en una vía de abordaje amplio, sección de la traquea en bisel, adelgazamiento de la piel, fijación de la porción cartilaginosa de la traquea lateralmente al borde de piel del colgajo inferior, fijación meticulosa de la mucosa de la porción membranosa al borde de piel del colgajo superior, y cuidados post-operatorio apropriado del traqueostoma


Subject(s)
Humans , Laryngectomy/adverse effects
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