[Andrological status of adolescents and its connection to anthropometric and hormonal descriptions in the students of technical college group].

The purpose of this investigation was to study the interrelation of andrological status with anthropometric and hormonal descriptions for age-specific features discovery of male sexual system pathological states at technical college students. 147 adolescents aged 15-17 years old were examined. Only 41 of them were found to have no abnormalities in their genital system development; in 35 adolescents sexual development was delayed; and 97 adolescents were found to have various andrological diseases (varicocele, phimosis, gynecomastia, testicular asymmetry, etc.) or clinical signs for development of these diseases. In 26 adolescences delayed sexual development was combined with the andrological pathology. The normal andrological status was usually accompanied with the highest frequency of low values of anthropometric indicators and indices that reflect the influence of various hormonal systems on the bodily constitution, as well as expressed anthropometricheterogeneity. In adolescents with andrological pathology or clinical signs for its development, in all anthropometric parameters the higher values were seen more frequently than low values against the background of highest group anthropometric homogeneity. Summative anthropometric characteristics of the adolescents group with delayed sexual development were between those of the adolescents groups with normal andrological status and andrological pathology The number of correlational relationships of anthropometric and hormonal indicators with the levels of cortisol and dehydroepiandrosteronesulphate was the lowest in the group of adolescents with normal andrological status as compared to their peers with delayed sexual development and andrological pathology. Only in the group of adolescents with normal andrological status the correlation analysis of data showed physiological influence of sexual hormones on anthropometric indicators. Thus, lower influence of sexual system hormones during this ontogenesis stage contributes to slowing down the process of sexual maturation both with the development of andrological pathology in adolescents.

[The prevalence of metabolic syndrome in an organized population].

Triple screening of industrial employees (city of Mirny, West Yakutia) was carried out in 1991-2007 in conformity with the WHO/CINDI protocol designed to elucidate risk factors of chronic non-infectious diseases. The study included 2221 subjects. Metabolic syndrome (MS) was diagnosed based on criteria of NCEP-ATP III Program modified in 2005. The prevalence of MS increased during 17 years more than three-fold in both men and women (from 6 3 to 23.0% and from 9.2 to 32.4% respectively). In other words, it grows continuously. The commonest components in the structure of MS in men and women were arterial hypertension, abdominal obesity, hyperglycemia in 1991 and arterial hypertension, low HDLP cholesterol level, abdominal obesity in 2000 and 2007 (additionally, hypertriglyceridemia in men).

[Association of erectile dysfunction with hypogonadism and metabolic syndrome among men of various age groups].

The integrated study included 184 men aged from 22 to 60 years who were formed into two groups, of the first and second period of middle age. The direct relation of both erectile dysfunction frequency and expressiveness from age was developed. The same dependence was found for hypogonadism clinical features, metabolic syndrome and its components, but inverse relation was detected between age and testosterone content in blood. The presence of erectile dysfunction was associated with testosterone level reduction, hypogonadism clinical features frequency, metabolic syndrome and most its components increase without the age. It was shown that first and second period of middle age men with erectile dysfunction did not display the difference in blood testosterone content, metabolic syndrome and its components frequency. Hence, the main risk factors of erectile dysfunction development form qualitatively already in young men; they accumulate quantitatively with age producing the androgenous disorders evolution.

[The role of prevention in decreasing endocrine pathology]. / K voprosu o roli profilaktiki v snizhenii éndokrinnoi patologii.

Time course of changes in the incidence of thyroid diseases and their association with other noncontagious chronic diseases (NCCD) have been evaluated among therapeutic patients hospitalized at Research Center for Clinical and Experimental Medicine of Siberian Division of Russian Academy of Medical Sciences in 1983-1995. The incidence of thyroid diseases was low in 1983, when prevention of iodine-deficiency diseases was a state program. In 1989, when iodine deficiency prevention was reduced, the incidence of cases with enlarged gland and its dysfunction has drastically increased. In 1995, when the system of population protection from endemic goiter virtually ceased to function, the incidence of thyroid diseases increased, including such serious diseases as diffuse toxic goiter, nodular goiter, primary hypothyrosis, and autoimmune thyroiditis; the number of patients in whom thyroid diseases were concomitant with other NCCD increased. These results demonstrate the principal significance of the preventive trend in public health.