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1.
Sci Rep ; 14(1): 982, 2024 01 10.
Article in English | MEDLINE | ID: mdl-38200020

ABSTRACT

The population with dementia is expected to rise to 152 million in 2050 due to the aging population worldwide. Therefore, it is significant to identify and intervene in the early stage of dementia. The Rey-Osterreth complex figure (ROCF) test is a visuospatial test scale. Its scoring methods are numerous, time-consuming, and inconsistent, which is unsuitable for wide application as required by the high number of people at risk. Therefore, there is an urgent need for a rapid, objective, and sensitive digital scoring method to detect cognitive dysfunction in the early stage accurately. This study aims to clarify the organizational strategy of aMCI patients to draw complex figures through a multi-dimensional digital evaluation system. At the same time, a rapid, objective, and sensitive digital scoring method is established to replace traditional scoring. The data of 64 subjects (38 aMCI patients and 26 NC individuals) were analyzed in this study. All subjects completed the tablet's Geriatric Complex Figure (GCF) test, including copying, 3-min recall, and 20-min delayed recall, and also underwent a standardized neuropsychological test battery and classic ROCF test. Digital GCF (dGCF) variables and conventional GCF (cGCF) scores were input into the forward stepwise logistic regression model to construct classification models. Finally, ROC curves were made to visualize the difference in the diagnostic value of dGCF variables vs. cGCF scores in categorizing the diagnostic groups. In 20-min delayed recall, aMCI patients' time in air and pause time were longer than NC individuals. Patients with aMCI had more short strokes and poorer ability of detail integration (all p < 0.05). The diagnostic sensitivity of dGCF variables for aMCI patients was 89.47%, slightly higher than cGCF scores (sensitivity: 84.21%). The diagnostic accuracy of both was comparable (dGCF: 70.3%; cGCF: 73.4%). Moreover, combining dGCF variables and cGCF scores could significantly improve the diagnostic accuracy and specificity (accuracy: 78.1%, specificity: 84.62%). At the same time, we construct the regression equations of the two models. Our study shows that dGCF equipment can quantitatively evaluate drawing performance, and its performance is comparable to the time-consuming cGCF score. The regression equation of the model we constructed can well identify patients with aMCI in clinical application. We believe this new technique can be a highly effective screening tool for patients with MCI.


Subject(s)
Cognitive Dysfunction , Dementia , Humans , Aged , Aging , Cognitive Dysfunction/diagnosis , Electric Power Supplies , Logistic Models , Tablets , Dementia/diagnosis
2.
Sensors (Basel) ; 23(12)2023 Jun 07.
Article in English | MEDLINE | ID: mdl-37420579

ABSTRACT

Compared with non-redundant manipulators, the self-motion of 7-DOF redundant manipulators results in an infinite number of inverse kinematics solutions for a desired end-effector pose. This paper proposes an efficient and accurate analytical solution for inverse kinematics of SSRMS-type redundant manipulators. This solution is applicable to SRS-type manipulators with the same configuration. The proposed method involves introducing an alignment constraint to restrain the self-motion and to decompose the spatial inverse kinematics problem into three independent planar subproblems simultaneously. The resulting geometric equations depend on the part of the joint angles, respectively. These equations are then computed recursively and efficiently using the sequences of (θ1,θ7), (θ2,θ6), and (θ3,θ4,θ5), generating up to sixteen sets of solutions for a given desired end-effector pose. Additionally, two complementary methods are proposed for overcoming the possible singular configuration and judging unsolvable poses. Finally, numerical simulations are conducted to investigate the performance of the proposed approach in terms of average calculation time, success rate, average position error, and the ability to plan a trajectory with singular configurations.


Subject(s)
Biomechanical Phenomena , Motion
3.
Appl Opt ; 62(9): 2338-2349, 2023 Mar 20.
Article in English | MEDLINE | ID: mdl-37132873

ABSTRACT

To improve the detection capability of satellite-based synthetic aperture radar, a large antenna array with a length scale of 100 meters is urgently needed. However, the structural deformation of the large antenna leads to phase errors, which will significantly reduce the antenna gain; hence, real-time and high-precision profile measurements of the antenna are essential for active compensation of the phase and thus improving the antenna gain. Nevertheless, the conditions of antenna in-orbit measurements are rather severe because of limited installation locations of measurement instruments, large areas, and long distance to be measured, and unstable measurement environments. To deal with the issues, we propose a three-dimensional displacement measurement method for the antenna plate based on laser distance measuring and digital image correlation (DIC). The proposed method uses the DIC method to retrieve the in-plane displacement information in combination with a laser range finder to provide depth information. A Scheimpflug camera is used to overcome the limitation of the depth of field of traditional cameras and enable clear imaging of the full field. Moreover, a vibration compensation scheme is proposed to eliminate the measurement error of the target displacement caused by the random vibration (within 0.01°) of the camera support rod. The results of the experiment in a laboratory setting show that the proposed method can effectively eliminate the measurement error caused by camera vibration (50 mm) and reduce the displacement measurement error to within 1 mm with a measurement range of 60 m, which can meet the measurement requirements of next-generation large satellite antennas.

4.
Front Neurol ; 12: 680474, 2021.
Article in English | MEDLINE | ID: mdl-34531812

ABSTRACT

The Rey-Osterrieth Complex Figure (ROCF) test is a commonly used neuropsychological assessment tool. It is widely used to assess the visuo-constructional ability and visual memory of neuropsychiatric disorders, including copying and recall tests. By drawing the complex figure, the functional decline of a patient in multiple cognitive dimensions can be assessed, including attention and concentration, fine-motor coordination, visuospatial perception, non-verbal memory, planning and organization, and spatial orientation. This review first describes the different versions and scoring methods of ROCF. It then reviews the application of ROCF in the assessment of visuo-constructional ability in patients with dementia, other brain diseases, and psychiatric disorders. Finally, based on the scoring method of the digital system, future research hopes to develop a new digital ROCF scoring method combined with machine learning algorithms to standardize clinical practice and explore the characteristic neuropsychological structure information of different disorders.

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