ABSTRACT
Clinical and histopathological features of 28 patients with Mullerian mixed tumours of the uterine corpus presenting to the Birmingham and Midland Hospital for Women between 1972 and 1977 are reviewed. The 5-year survival value for this group of patients was 25% with 53.5% of patients dying within 12 months of diagnosis. The most important finding of prognostic value was the extent of the tumour at the time of diagnosis and where this was localized to the uterus, there was a 50% 5-year survival. The presence of specific types of heterotopic elements or numbers of mitotic elements were not correlated with outcome. Five patients had previously received radium for induction of a radiation menopause and the relevance of this treatment and other factors in the aetiology of the tumour are discussed.
Subject(s)
Neoplasms, Germ Cell and Embryonal/pathology , Uterine Neoplasms/pathology , Aged , Cervix Uteri/pathology , Female , Follow-Up Studies , Humans , Middle Aged , Neoplasms, Germ Cell and Embryonal/therapy , Uterine Neoplasms/therapyABSTRACT
In a randomised prospective study of 68 women in spontaneous labour half were allocated to an ambulant group and half to a recumbent group. The duration of labour was significantly shorter, the need for analgesia significantly less, and the incidence of fetal heart abnormalities significantly smaller in the ambulant group than in the recumbent group. Apgar scores at one and five minutes were also significantly greater in the ambulant group. More patients in the recumbent group required augmentations with oxytocic drugs. There was no statistically significant difference in the third stage loss in the two groups. Ambulation in labour should be encouraged: it may bring human benefits while allowing the advantages of hospital supervision.