Practical Steps to Improve Air Flow in Long-Term Care Resident Rooms to Reduce COVID-19 Infection Risk.

The potential for spread of COVID-19 infections in skilled nursing facilities and other long-term care sites poses new challenges for nursing home administrators to protect patients and staff. It is anticipated that as acute care hospitals reach capacity, nursing homes may retain COVID-19 infected residents longer prior to transferring to an acute care hospital. This article outlines 5 pragmatic steps that long-term care facilities can take to manage airflow within resident rooms to reduce the potential for spread of infectious airborne droplets into surrounding areas, including hallways and adjacent rooms, using strategies adapted from negative-pressure isolation rooms in acute care facilities.

Artefact mimicking torsades: treat the patient not the ECG.

ECG interpretation is an essential skill in the management of the acutely unwell patient and in addition to history taking and physical examination has been shown to have a significant effect on referral patterns to cardiologists. One of the basic initial steps in ECG interpretation is assessment for the presence of artefact which if present can dramatically influence the diagnosis. The most common sources of artefact are tremor e.g. in Parkinson's disease, loose skin electrodes and electromagnetic interference from other medical devices and mobile phones. The Medicines and Healthcare products Regulatory Agency in the UK advises that mobile phones should be kept at least one metre away from equipment that is sensitive to electromagnetic interference. The possibility that artefact is the cause of the ECG appearance should always be considered if bizarre ECG changes are present particularly in an asymptomatic patient. The ECG should always be interpreted in the context of the patient's condition. If artefact is thought to be the cause of the ECG appearance, then any contributory factors present should be corrected and the ECG should be repeated before invasive investigations are undertaken or treatment is administered.

Achilles tendon rupture: surgical versus non-surgical treatment.

OBJECTIVE: To ascertain the treatment method of choice for Achilles tendon rupture, which results in the most favourable functional outcome. METHODS: A comprehensive literature search was performed to retrieve relevant English language articles comparing surgical with non-surgical treatment. RESULTS: The literature search identified five prospective randomised controlled trials, three of which compare surgical with non-surgical treatment, one which compares functional early mobilisation with cast immobilisation after surgical repair and one which compares functional and cast immobilisation in non-surgical management of Achilles tendon rupture. CONCLUSION: Surgical treatment of Achilles tendon rupture is associated with a significantly lower incidence of re-rupture and therefore is the treatment method of choice. Non-surgical treatment may be acceptable for patients who refuse surgery or who are unfit for surgery. Functional early mobilisation appears to be associated with an improved functional outcome and should be considered in preference to plaster cast immobilisation where appropriate.

Accuracy of abdominal examination in the diagnosis of non-ruptured abdominal aortic aneurysm.

BACKGROUND: Early detection of abdominal aortic aneurysms (AAA) is paramount to reducing the very high mortality rates associated with rupture. This literature review was undertaken to assess the accuracy of abdominal examination in the detection of non-ruptured AAA. METHOD: A comprehensive literature search was performed to retrieve prospective studies comparing the accuracy of physical examination (PE) in the diagnosis of non-ruptured AAA confirmed by the gold standard, ultrasonography. RESULTS: The sensitivity of PE in the diagnosis of AAA ranges from 33% to 100%, the specificity from 75% to 100%, and the positive predictive value from 14% to 100%. Detection rates increase with increasing aortic diameter, increasing age, male sex, presence of recognisable risk factors, examination by an experienced clinician, PE directed specifically towards the detection of AAA, prevalence of AAA in study population, and thin patients. CONCLUSION: Clinical examination cannot be relied upon to exclude AAA. Larger aneurysms are usually palpable and more likely to be detected on examination especially in thin patients. Due to the poor sensitivity of PE together with the high sensitivity and specificity of ultrasound, obese patients in whom there is difficulty palpating an aneurysm, despite a history suggestive of possible non-ruptured AAA, should be referred for ultrasound examination to assist with the diagnosis.

Anaphylactoid reactions to intravenous N-acetylcysteine: a prospective case controlled study.

INTRODUCTION: Since its introduction in 1977, intravenous N-acetylcysteine has become the treatment of choice for paracetamol overdose. The aim of our study was to investigate the existence of predictive factors in the likelihood of developing anaphylactoid reactions to N-acetylcysteine. METHODS: Prospective case-controlled study of all patients who presented to our emergency department (ED) between January 1997 and June 1999, and who were treated with intravenous N-acetylcysteine on the short stay observation ward. RESULTS: Sixty-four patients received N-acetylcysteine infusions; thirty-one (48.4%) developed an anaphylactoid reaction. Nineteen patients who reacted were commenced on N-acetylcysteine prior to receipt of paracetamol concentrations and fifteen (48.4%) were categorised as high-risk. Seventy-one percent of reactions occurred within the first 15 min. Thirteen patients who developed a reaction, had levels which fell below the treatment lines. The levels of a further nine reactors lay above the high-risk but below the normal-risk lines. Only five patients who reacted had levels above the normal-risk line. Two of the patients who reacted to intravenous N-acetylcysteine presented at a later date with a further paracetamol overdose. Both required treatment with intravenous N-acetylcysteine, the first bag being infused over one hour. Neither developed a reaction. CONCLUSION: We report a substantially higher incidence of anaphylactoid reactions to intravenous N-acetylcysteine than has previously been documented. It appears that these reactions are more likely to occur in high-risk patients, when plasma paracetamol concentrations were found to be below the treatment lines and in late presenters. Perhaps, giving the loading dose of N-acetylcysteine over 60 min could reduce the incidence of adverse reactions.

Activated charcoal: the untold story.

Introduction. To identify the prevalence and appropriateness of prescribing activated charcoal in the management of acute poisoning and to document patient compliance with treatment.Methods. A prospective study was conducted, between October 1998 and September 1999, on patients attending our accident and emergency department, with a history of overdose. Overdoses were classified as potentially toxic or non-toxic according to the history and/or information received from the National Poisons Information Service.Results. Two hundred and seventy five patients presented following overdose; 17% within one hour, 102 were prescribed charcoal (37.1%) but of these, 40 (39%) refused it, and of the 62 patients (61%) who accepted charcoal only 15 (24.2%) took all that was prescribed. Patients were 5.4 times more likely to take charcoal if they had taken a potentially toxic overdose. Of those who presented within one hour and were judged to have taken a potentially toxic overdose, only three patients took the full-prescribed amount.Conclusion. We report a substantially greater proportion of patients (39%) refusing charcoal than previously reported (9.9%). The widespread availability of TOXBASE Copyright should help redress this discrepancy.