[The application of transcranial magnetic stimulation for the functional diagnostics of motor disturbances in the patients presenting with ischemic stroke].

AIM: To estimate the informative value of transcranial magnetic stimulation (TMS) as a tool for the functional diagnostics of motor disturbances and to evaluate its remedial potential in the patients presenting with ischemic stroke (IS) and motility disorders in the acute phase of the disease and during the early rehabilitation period. MATERIALS AND METHODS: The present study included the comprehensive examination of 112 patients (mean age 59.2 +/- 5.67 years) with the newly emerged hemispheric IS in the basin of the right (n = 53) and left (n = 59) middle cerebral artery (MCA) in the acute phase of the disease and during the early rehabilitation period associated with a moderate neurologic deficit. Moreover, TMS was used to examined 30 subjects (mean age 57.8 +/- 4.33 years) presenting without neurological pathology who comprised the control group for the comparison of the motor evoked potentials (MEP). Correlation between different MEP values and numerical score estimates of neurological deficit based on the NIH stroke scale was calculated using nonparametric Spearman's correlation coefficient. RESULTS: In 42 (34.4%) patients with IS, MEP on the affected side were missing which was later manifested as the low rehabilitative potential for the restoration of the motor functions. In 70 of the 112 patients (65.6%) MEP were registered from the paretic limbs by TMS of the motor centers of the affected hemisphere even though with a decreased amplitude and increased latency that facilitated the well apparent recovery of the motor function during the rehabilitation process in these patients (from 5.4 +/- 0.3 points to 1.3 +/- 0.5 points, p < 0.05). The persistence of MEP during TMS of the affected hemisphere in the patients with IS can be considered as the conservation of the rehabilitation potential for the recovery of the motor functions. All the time-amplitude parameters of MEP in the upper extremities significantly correlated with the NIHSS scores. In the lower extremities correlation was statistically significant for the MEP amplitude parameters and the latency difference between the affected and unaffected sides. CONCLUSION: TMS with the determination of the time and amplitude parameters of MEP is a sensitive method for the quantitative assessment of the functional status of the motor system in the patients presenting with ischemic stroke and motility disorders in the acute phase of the disease and during the early rehabilitation period.

[Effect of rehabilitation using antihomotoxic drug together with energy stabilizing electromagnetic therapy on morphological, biochemical, and system immunity indices in children with recurrent bronchitis].

There is now good evidence that the use of electromagnetic millimeter waves the following curative effects: analgesic, normalization of relations or increased formation of neurohumoral substances. The introduction of a therapeutic practice complex biological drugs that trigger, not overwhelming the body auxiliary immunological reaction, based on the activation of the regulation clones of T-lymphocytes and helper functions, is an important step in achieving a qualitatively level of health patients with chronic disease.

[Principles of post stroke rehabilitation].

Clinical management of patients with acute cerebral blood flow depends on the cause and location of violation, clinical manifestations of the disease. Acute stroke patients during the course conducted in specialized intensive care and neurological departments of hospitals. The most frequent problems in patients who have had a stroke, is a violation of the motor and koordinatornye functions, language, vision and sensitivity, loss of skills and self-service moves. It is with these effects occur patients after discharge from hospital.

[Erythrocyte membrane as an object of influence of physiotherapeutic factors].

The authors presented in the article the survey of literature data and own observations on the influence of the most practiced therapeutic physical factors (electrical, ultrasound and light) on red blood cell membrane. Low intensive laser makes an impact on protein-lipid interactions in membranes of red blood cells, has antioxidant effect and improves the function of red blood cells. It proves the use of laser irradiation in the treatment of different diseases. Heat liberation and cavitation are the most important factors of ultrasound effect on red blood cell membrane. It was established by the method of the correlation spectroscopy that direct and alternating current at its 0.22 mA/cm density decreases the diameter of monomolecular protein globules of human serum albumin. This effect is seen increased under the augmentation of exposure time and current strength. Obtain results show direct effect of the electric current on albumin as well as protein component of blood cell membrane that may be of importance in molecular mechanisms of treatment effects of this physiotherapy factor. The effect of laser irradiation, ultrasound and electrical current depend on the intensity and the duration of the effect. Clarification of the effects of molecular mechanisms on red blood cell membrane may help to develop effective physiotherapeutic technologies to use in different areas of medicine.