ABSTRACT
OBJECTIVE: Our objective was to determine the ease of installation and use of relatively inexpensive and free software applications that allow Macintosh users to receive and view CT images from a Digital Imaging and COmmunication in Medicine-compliant imaging network. CONCLUSION: Simple-to-use Macintosh-based options to transfer and view images are readily available and easily installed by users with minimal computer expertise.
Subject(s)
Radiology Information Systems , Software , Tomography, X-Ray Computed , Humans , Microcomputers , Radiology Information Systems/standards , Tomography, X-Ray Computed/standardsABSTRACT
UNLABELLED: In the clinical application of activation PET studies with 15O-water, optimal PET images are required when the high activity of a nearby lesion might affect the activated area. METHODS: To determine the optimal time for data acquisition of PET images, we performed serial dynamic PET measurements in five patients with cerebral arteriovenous malformation (AVM). All AVMs were closest to the motor cortices, and the activation task was opponent finger movement contralateral to the AVM. Activation PET and MR images were coregisterated for localization of activated foci. RESULTS: Time-activity curves of the nidus and normal cortex from the dynamic PET data demonstrated a discrepancy in peak time and significant radioactivity increase in the nidus during the early phase. Elimination of the initial PET data provided better contrast in activated foci without affecting the calculated cerebral blood flow of other areas. CONCLUSION: Delayed data acquisition can avoid interference of the AVM nidus with the activated area.
Subject(s)
Intracranial Arteriovenous Malformations/diagnostic imaging , Oxygen Radioisotopes , Tomography, Emission-Computed/methods , Water , Adult , Cerebrovascular Circulation/physiology , Female , Humans , Intracranial Arteriovenous Malformations/diagnosis , Magnetic Resonance Imaging , Male , Middle Aged , Motor Cortex/diagnostic imaging , Motor Cortex/pathology , Time FactorsABSTRACT
Identical sets of H2(15)O-PET brain activation data regarding vibrotactile stimulation and voluntary motion of the fingers in seven young normal subjects, together with the MRI, were analyzed in three PET centers by means of each center's own method of anatomical standardization to Talairach's frame. Every center used a linear or segmentally linear transformation with various number of scaling factors. A variation of 6-8 mm in each axis was observed in the foci localization due to the difference in the transformation principle and the measured brain size. Between-subject variation was similar in all the centers. Since different standardization methods define different coordinate systems, a cautious attitude should be taken to comparing results analyzed at different centers.
Subject(s)
Brain Mapping/methods , Motor Cortex/anatomy & histology , Motor Cortex/diagnostic imaging , Oxygen Radioisotopes , Tomography, Emission-Computed/methods , Adult , Cerebrovascular Circulation , Fingers , Humans , Magnetic Resonance Imaging , Male , Motor Cortex/physiology , Physical Stimulation , Vibration , WaterABSTRACT
In order to clarify the roles played by the primary motor cortex and the supplementary motor area in the execution of complex sequential and simple repetitive finger movements, regional cerebral blood flow (rCBF) was measured with PET using 15O-labelled water in five normal subjects. The PET data of each individual subject co-registered to his own MRI, was analysed. Compared with the resting condition, the mean rCBF was markedly increased in the contralateral sensorimotor cortex (M1-S1) and moderately increased in the contralateral cingulate gyrus and putamen in both the simple and complex motor tasks. During the complex motor task, in addition to the above, the mean rCBF was markedly increased in the supplementary motor area and the contralateral premotor area, and moderately increased in the ipsilateral M1-S1 and cerebellum. In the supplementary motor area, there was a moderate rCBF increase also during the simple task. However, comparison of the mean rCBF increase against the resting condition between the two tasks revealed a greater increase during the complex task than in the other only in the supplementary motor area and the ipsilateral M1-S1. Thus, in agreement with our previous electrophysiological findings, not only the supplementary motor area but also the M1-S1 seems to play an important role in the execution of complex sequential finger movements.
