ABSTRACT
Results of a morphological study of coronary arteries from 90 patients who died from ischemic heart disease and arterial hypertension are presented. Various types of fibrous plaques damage and their features in arterial hypertension were morphologically found.
Subject(s)
Coronary Vessels/pathology , Myocardial Ischemia/pathology , Aged , Aged, 80 and over , Female , Humans , Hypertension/complications , Male , Middle Aged , Myocardial Ischemia/complicationsABSTRACT
Immunomorphological study of the liver in patients died from diffuse peritonitis showed specific changes in the number and morphology of Kupffer cells and endotheliocytes in various zones of the acinus in peritonitis of different origin.
Subject(s)
Liver/metabolism , Liver/pathology , Adult , Aged , Antigens, CD/biosynthesis , Antigens, Differentiation, Myelomonocytic/biosynthesis , Autopsy , Endothelium/metabolism , Female , Hepatocytes/metabolism , Humans , Immunohistochemistry , Kupffer Cells/metabolism , Male , Middle Aged , Peritonitis/pathology , Platelet Endothelial Cell Adhesion Molecule-1/biosynthesisABSTRACT
The effect of Gram-negative bacterial lipopolysaccharide on rat hepatocytes and sinusoidal cells was studied. The damage and regeneration potential of the liver were evaluated by activation of perisinusoidal Ito cells and proliferative activity of liver cells. Compensatory and repair reactions in the liver induced by lipopolysaccharide manifested by proliferation of liver cells and reversible activation of Ito cells without their transdifferentiation into myofibroblasts.
