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1.
Pak J Pharm Sci ; 36(2(Special)): 681-685, 2023 Mar.
Article in English | MEDLINE | ID: mdl-37548209

ABSTRACT

To study the clinical effect of psychiatric nursing-based vancomycin in patients with staphylococcus aureus infectious skin disease. A retrospective analysis was performed on 100 patients with staphylococcus aureus infectious skin disease admitted to our hospital from March 2019 to July 2020. Al patients received psychiatric nursing and were divided into control group (mupiroxine) and experimental group (vancomycin) according to the treatment mode, with 50 patients in each group. The effective rate of treatment, adverse reactions, disappearance time of dermatological clinical symptoms and recurrence after one course of treatment were compared between the two groups. The effective rate of the experimental group was significantly higher than that of the control group (P<0.05).The incidence of adverse reactions and the disappearance time of clinical symptoms in the experimental group were significantly lower than those in the control group (P<0.05). After one course of treatment, the number of patients with recurrence in the experimental group was significantly lower than that in the control group (P<0.05). Vancomycin might be a boon for patients with staphylococcus aureus infectious skin diseases, with good effectiveness and safety profiles.


Subject(s)
Methicillin-Resistant Staphylococcus aureus , Oxazolidinones , Psychiatric Nursing , Skin Diseases, Infectious , Staphylococcal Infections , Humans , Vancomycin/therapeutic use , Vancomycin/pharmacology , Staphylococcus aureus , Anti-Bacterial Agents/adverse effects , Linezolid/pharmacology , Oxazolidinones/therapeutic use , Retrospective Studies , Acetamides/pharmacology , Staphylococcal Infections/drug therapy , Treatment Outcome , Skin Diseases, Infectious/chemically induced , Skin Diseases, Infectious/drug therapy
2.
Zhongguo Zhong Yao Za Zhi ; 48(3): 608-613, 2023 Feb.
Article in Chinese | MEDLINE | ID: mdl-36872223

ABSTRACT

This paper introduced the overview of the "eight trends" of Chinese medicinal materials(CMM) industry in 2021, analyzed the problems of CMM production, and put forward development suggestions. Specifically, "eight trends" could be summarized as follows.(1) The growing area of CMM tended to be stable, and some provinces began to release the local catalog of Dao-di herbs.(2) The protection process of new varieties accelerated, and a number of excellent varieties were bred.(3) The theory of ecological cultivation was further enriched, and the demonstration effect of ecological cultivation technology was prominent.(4) Some CMM realized complete mechanization and formed typical model cases.(5) The number of cultivation bases using the traceability platform increased, and provincial internet trading platforms were set up.(6) The construction of CMM industrial clusters accelerated, and the number of provincial-level regional brands increased rapidly.(7) Many new agricultural business entities were founded nationwide, and a variety of methods were used to drive the intensified development of CMM.(8) A number of local TCM laws were promulgated, and the management regulation of food and medicine homology substances catalogs was issued. On this basis, four suggestions for CMM production were proposed.(1) It is suggested to speed up the formulation of the national catalog of Dao-di herbs and carry out the certification of Dao-di herbs production bases.(2) Ecological planting of forest and grassland medicine should be further strengthened in terms of technical research and promotion based on the principle of ecological priority.(3) The basic work of disaster prevention should be paid more attention and technical measures for disaster mitigation should be developed.(4) The planted area of commonly used CMM should be incorporated into the national regular statistical system.


Subject(s)
Commerce , Industry , Agriculture , Certification , China
3.
Pain Physician ; 26(2): 187-196, 2023 03.
Article in English | MEDLINE | ID: mdl-36988364

ABSTRACT

BACKGROUND: Pain-depression comorbidity has become a great burden to individuals and society. Nevertheless, the mechanisms underlying comorbid diseases have still not been fully revealed. Ultrasound-guided pulsed radiofrequency (PRF) on peripheral nerves, which produces remarkable analgesia via high-frequency electromagnetic energy, has become a main, minimally invasive treatment for chronic neuropathic pain. OBJECTIVES: The aim of this study was to explore the effect of ultrasound-guided PRF on the sciatic nerve of spared nerve injury (SNI) rats to relieve pain-induced depression. STUDY DESIGN: Experimental trial in rats. SETTING: The research took place in the Laboratory of The First Affiliated Hospital of Wenzhou Medical University. METHODS: Sixty male Wistar rats were randomly divided into a sham group, an SNI group, an SNI + free-PRF group, and an SNI + PRF group. Ultrasound-guided PRF was applied to the sciatic nerve on day 7 after SNI. The basal paw mechanical withdrawal threshold (PMWT) was evaluated as a measure for pain-related behavior, and a  sucrose preference test was performed as a measure for depression-related behavior. The expression levels of spinal interferon regulatory factor 8 (IRF8) and of brain-derived neurotrophic factor (BDNF) in the prefrontal cortex (PFC) were also studied on days 21 and 42. RESULTS: The results showed that the PMWT was significantly decreased in rats following SNI operation; the decreased levels of PMWT were reversed in the SNI + PRF group after the application of PRF on the sciatic nerve on day 7. There were no statistically significant differences among the groups in the sucrose preference rate on day 21 after SNI operation. The sucrose preference rate on day 42 was higher in the SNI + PRF group than in the SNI + free-PRF group. Western blot and reverse transcription polymerase chain reaction also demonstrated that ultrasound-guided PRF on the sciatic nerve downregulated overexpression of spinal IRF8 and increased the levels of BDNF in the PFC. LIMITATIONS: This study was performed using only an SNI rat model which cannot represent all rodent neuropathic pain models. Only the short-term effectiveness of ultrasound-guided PRF on the sciatic nerve of SNI rats was investigated. The BDNF changes of other important brain areas were not taken into consideration in this study. CONCLUSIONS: These findings suggest that ultrasound-guided PRF on sciatic nerve could alleviate pain-induced depression. The mechanisms of this treatment may be involved in the downregulated spinal IRF8 and the increased BDNF in PFC.


Subject(s)
Neuralgia , Pulsed Radiofrequency Treatment , Rats , Male , Animals , Rats, Sprague-Dawley , Rats, Wistar , Pain Management , Brain-Derived Neurotrophic Factor/metabolism , Depression/therapy , Pulsed Radiofrequency Treatment/methods , Neuralgia/therapy , Neuralgia/metabolism , Interferon Regulatory Factors , Sciatic Nerve/injuries , Prefrontal Cortex/metabolism , Ultrasonography, Interventional , Disease Models, Animal
4.
Zhongguo Zhong Yao Za Zhi ; 47(19): 5389-5396, 2022 Oct.
Article in Chinese | MEDLINE | ID: mdl-36472047

ABSTRACT

Green agriculture has become the "wind vane" of agricultural reform in the new era. The development concept of Chinese materia medica(CMM) ecological agriculture and the emergence of new technologies provide momentum for the supply of high-quality green ecological products. As special ecological products, Dao-di herbs have medicinal, economic, ecological, and cultural values. The ecological planting of CMM and the value realization of ecological products are of great significance for the high-quality development of CMM agriculture and for prospering agriculture by improving quality. Therefore, this paper reviews the development status and typical cases, and puts forward the advantages of ecological product value realization of Dao-di herbs. On this basis, a value accounting system for ecological products of CMM was constructed from three aspects: supply services, ecological services, and cultural services. Finally, the suggestions for realizing the value of CMM ecological products are put forward.(1)It is suggested to strengthen the practice of ecological planting and production of CMM, and innovate the value realization model of ecological products.(2)The ecological planting bases of Dao-di herbs should be constructed to enhance the supply capacity of high-quality ecological products.(3)The quality and safety of ecological CMM should be improved to create the ecological planting brand of Dao-di herbs.(4)The ecological product value system and mechanism should be improved for realizing the value of CMM ecological products.(5)The education and publicity should be strengthened to raise the public awareness of the value of CMM ecological products.


Subject(s)
Drugs, Chinese Herbal , Materia Medica , Plants, Medicinal , Medicine, Chinese Traditional , China
5.
Mar Pollut Bull ; 184: 114126, 2022 Nov.
Article in English | MEDLINE | ID: mdl-36162291

ABSTRACT

Understanding the accumulation mechanism for beached plastics is important for marine debris research. Similar to the global accumulation pattern for beached plastics, we find that along the remote south coast of Western Australia (SCWA) white, hard, microplastics dominate the microplastic pollution accumulating on beaches. We estimate that along the SCWA, plastics are present at a density of 2.01 items·m-2, but also find that the density of plastic pollution is higher at the eastern end of bays. Significantly fewer plastics were found after easterly winds (austral summer-prevailing winds), and regional physical ocean process, including the Leeuwin Current, and the Ekman transport effect may be relevant to the rate of plastic accumulation on SCWA beaches.


Subject(s)
Microplastics , Plastics , Waste Products/analysis , Western Australia , Environmental Monitoring , Bathing Beaches
6.
Zhongguo Zhong Yao Za Zhi ; 47(13): 3675-3680, 2022 Jul.
Article in Chinese | MEDLINE | ID: mdl-35850822

ABSTRACT

The internationalization of traditional Chinese medicine(TCM) is one of the strategic development objectives in China, which has been incorporated into the national strategy as an important part of the Belt and Road Initiative development strategy. As the basis and prerequisite of TCM development, Chinese materia medica(CMM) has a direct impact on the internationalization of TCM. The International Organization for Standardization(ISO) is a global organization composed of national standardization bodies, and the ISO standards impact the world's economy, trade, communication and cooperation. Based on a brief introduction to ISO/Traditional Chinese Medicine Technical Committee(ISO/TC 249), this study elaborates the necessity of establishing ISO standards for CMM and analyzes the current status and challenges faced by the formulation of international standards for CMM. Finally, this study puts forward the development strategy of international standards for CMM. Specifically, efforts should be made to develop top-level design with international market demands as the guidance and improve the quality of standards to accelerate the transformation of domestic high-quality standards into international standards. Moreover, measures should be taken to give full play to the positive role of enterprises in the formulation of standards, vigorously cultivate compound talents for international standardization of TCM, and constantly strengthen international cooperation. The experience and thinking are of guiding significance for the scientific, efficient and reasonable formulation of high-quality ISO standards for CMM in the future.


Subject(s)
Drugs, Chinese Herbal , Materia Medica , China , Humans , Medicine, Chinese Traditional , Reference Standards
7.
Sci Rep ; 12(1): 8976, 2022 05 28.
Article in English | MEDLINE | ID: mdl-35643858

ABSTRACT

In the evaluation problem of fishing vessel fishing capacity, the imperfect evaluation index system and the methods of evaluation indexes are mostly artificial qualitative evaluation methods, which lead to strong subjectivity and fuzziness as well as low accuracy of evaluation results. Therefore, this study introduces cloud model theory on the basis of improving the evaluation index system, converts the artificial qualitative evaluation results into the digital characteristics of clouds, realizes the mutual transformation of qualitative evaluation and quantitative evaluation, and improves the accuracy of evaluation results. Taking the trawler as an example, the cloud model method is used to evaluate the fishing capacity, and the result obtained is (77.1408, 1.6897, 0.0), the result obtained by the fuzzy comprehensive evaluation method is 76.664785, and the result obtained by the cloud center of gravity evaluation method is 0.7919. Compared with the other two methods, the cloud model method uses three numerical characteristics to describe the results, and combining the different numerical characteristics meanings, the evaluation results can be judged to be accurate, and the influence of ambiguity on the results is greatly reduced. Meanwhile, the evaluation results can be presented in the form of pictures, and the results are more intuitive; in addition, the cloud model of the evaluation results is compared with the standard cloud model for similarity, which improves the credibility and authenticity of the results.


Subject(s)
Hunting
8.
Nano Lett ; 22(13): 5175-5181, 2022 Jul 13.
Article in English | MEDLINE | ID: mdl-35714056

ABSTRACT

Recently, exciton-polaritons in lead halide perovskite microcavities have been extensively investigated to address striking phenomena such as polariton condensation and quantum emulation. However, a critical step in advancing these findings into practical applications, i.e., realizing electrically pumped perovskite polariton light-emitting devices, has not yet been presented. Here, we devise a new method to combine the device with a microcavity and report the first halide perovskite polariton light-emitting device. Specifically, the device is based on a CsPbBr3 capacitive structure, which can inject the electrons and holes from the same electrode, conducive to the formation of excitons and simultaneously maintaining the high quality of the microcavity. In addition, highly polarized polariton emissions have been demonstrated due to the optical birefringence in the CsPbBr3 microplate. This work paves the way for realizing practical polaritonic devices such as high-speed light-emitting devices for information communications and inversionless electrically pumped lasers based on perovskites.

9.
Zhongguo Zhong Yao Za Zhi ; 47(5): 1144-1152, 2022 Mar.
Article in Chinese | MEDLINE | ID: mdl-35343138

ABSTRACT

This study steps through the future perspectives and gives the development suggestions of Chinese medicinal materials(CMM) industry by presenting the characteristics and open problems during the 13 th Five-Year Plan period. The development of CMM industry presents the following trends:(1)the development of Dao-di herbs speeds up with the increasing demand for high-quality CMM;(2)the mismatch between supply and demand is aggravating, which presses for supply-side structural reform;(3)ecological planting will become the core mode of production and bolster rural revitalization;(4)the demand for CMM with both medical and edible values keeps growing, and the antibiotic-free feed policy brings significant opportunities;(5)the "Internet Plus CMM" wave emerges, which promotes the construction of traceability system. Finally, we put forward the following suggestions for the sustainable development of CMM industry:(1)optimizing the layout for the production of Dao-di herbs according to local conditions;(2)strengthening the commercialization of the seeds and the breeding, multiplication, and extension of CMM to accelerate the realization of specialized seed production, mechanized seed processing, localized variety layout, and county-based unified seed supply;(3)ensuring the safety of pesticide use and accelerating the registration of special pesticides;(4)promoting both theoretical and practical research on ecological production of CMM;(5)publicizing the demonstration and popularization of CMM traceability system. Overall, significant progress has been achieved in the CMM industry during the 13 th Five-Year Plan period, and this industry is in a critical stage of high-quality development, facing both challenges and opportunities.


Subject(s)
Drugs, Chinese Herbal , Medicine, Chinese Traditional , China , Drugs, Chinese Herbal/analysis , Industry , Plant Breeding
10.
Nano Lett ; 22(3): 1233-1241, 2022 Feb 09.
Article in English | MEDLINE | ID: mdl-35041438

ABSTRACT

Materials with a quasi-one-dimensional stripy magnetic order often exhibit low crystal and magnetic symmetries, thus allowing the presence of various energy coupling terms and giving rise to macroscopic interplay between spin, charge, and phonon. In this work, we performed optical, electrical and magnetic characterizations combined with first-principles calculations on a van der Waals antiferromagnetic insulator chromium oxychloride (CrOCl). We detected the subtle phase transition behaviors of exfoliated CrOCl under varying temperature and magnetic field and clarified its controversial spin structures. We found that the antiferromagnetism and its air stability persist down to few-layer samples, making it a promising candidate for future 2D spintronic devices. Additionally, we verified the magnetoelastic coupling effect in CrOCl, allowing for the potential manipulation of the magnetic states via electric field or strain. These virtues of CrOCl provide us with an ideal platform for fundamental research on spin-charge, spin-phonon coupling, and spin-interactions.

11.
Zhongguo Zhong Yao Za Zhi ; 47(24): 6810-6816, 2022 Dec.
Article in Chinese | MEDLINE | ID: mdl-36604930

ABSTRACT

"Medicine and food homology" is a precious health care concept rooted in the culture of Chinese medicine and plays an important role in the development of the national health industry. It is consistent with the current global trend that food and medicine are mutually penetrating. Accordingly, the Chinese medicinal materials with edible values have an increasing production scale. Especially, in the context that the development of Chinese medicinal materials is switching from pursuing quantity to quality, the food field has become the main market for the new production capacity of Chinese medicinal materials, which has presented a broad prospect. However, the quality standards of raw materials, production methods, and administration ways vary between the materials for edible and medicinal purposes. Specifically, the food for medicinal use on the market cannot meet the quality standards of medicinal mate-rials, while the medicinal materials fail to meet the taste requirements as food. As a result, these problems cause difficulties in market circulation and supervision. In this paper, we analyzed the formation of Chinese medicinal materials with edible values, compared the food with medicinal value, common food, and functional food, and analyzed the different quality requirements of Chinese medicinal materials used in different scenarios. Further, we advised the differential development of Chinese medicinal materials in different directions(edible or medicinal use) from production to supervision. Including:(1) In the variety registration of Chinese medicinal materials with edible values, the variety breeding direction should be announced according to the requirements that medicinal materials care more about the content of active ingredients and food use materials preferentially need to meet the requirements of edible palatability.(2) Differentiation can be reflected in the selection of cultivation mode and planting and processing technology of medicinal materials, The differential production technical specification of medicinal materials with edible values should be developed. Such as the "simulated cultivation" mode is encouraged in the plant of medicinal materials to ensure its quality and the strict management of inputs and sufficient cultivation years should be guaranteed. While for edible medicinal materials, more kinds of cultivation techniques can be selected according to their processing methods.(3) The market supervision of medicinal materials with edible values should be guided by the purpose of their sales and use, which depends on the accurately recognize of the relationship between the properties of medicinal materials with edible values and the situation of pharmacopeia collection.(4) During publicity, when used as ordinary food and health food medi-cinal materials, it should be noticed that the publicity of the product's efficacy must meet the requirements of corresponding regulations.


Subject(s)
Drugs, Chinese Herbal , Plants, Medicinal , Humans , Medicine, Chinese Traditional , Plant Breeding , Food , China
12.
China CDC Wkly ; 3(51): 1089-1092, 2021 Dec 17.
Article in English | MEDLINE | ID: mdl-34938587

ABSTRACT

WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: Oncomelania hupensis(O. hupensis) and livestock are main infection sources of schistosomiasis. The schistosome infected O. hupensis and livestock's feces are important risk factors in the transmission of schistosomiasis. WHAT IS ADDED BY THIS REPORT?: The potential risks of schistosomiasis transmission remain prevalent, giving an early warning to local government with information on existing transmission risks. It is expected that the effectiveness and efficiency of schistosomiasis surveillance could be improved by conducting rapid risk assessment at the beginning of transmission season. WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: Rapid risk assessment is essential in early detection and the active monitoring of indicators of the transmission risks of schistosomiasis in endemic areas. This could work synergistically with surveillance system to minimize infections and prevent rebounds of endemic schistosomiasis outbreaks.

13.
Zhongguo Zhong Yao Za Zhi ; 46(19): 4930-4935, 2021 Oct.
Article in Chinese | MEDLINE | ID: mdl-34738386

ABSTRACT

The endophytes of medicinal plants play an important role in promoting the quality formation of the host. Therefore, this paper made a review of endophytes of medicinal plant Atractylodes lancea. According to previous studies, A. lancea boasts endophytes, such as fungi, bacteria, and actinomycetes, among which the beneficial microorganisms help the growth and development of A. lancea. There is a close interaction between the volatile oil of A. lancea and endophytes. Different endophytes vary in regulating the composition and content of the volatile oil of A. lancea, which might contribute to the quality formation of A. lancea. However, the information of the endophytic flora of A. lancea obtained by traditional culture and isolation is not enough to reflect the real situation of the endophytes of A. lancea. Little is known about the endophytes of A. lancea from different chemical types and different habitats, which is not conducive to the study of the ecological relationship between A. lancea and endophytes and limits the development and utilization of the endophytes. Therefore, at the end of this paper, the authors put forward suggestions for future research on endophytes in A. lancea, including:(1)mining the core endophyte resources of A. lancea by combining high-throughput sequencing with traditional culture and isolation;(2)exploring the relationship between the diversity of endophytes and chemical types of A. lancea;(3)strengthening the application of endophytes in A. lancea cultivation, in order to facilitate the cultivation efficiency and quality of A. lancea.


Subject(s)
Atractylodes , Oils, Volatile , Plants, Medicinal , Endophytes , Fungi
15.
Zhongguo Zhong Yao Za Zhi ; 46(8): 1883-1892, 2021 Apr.
Article in Chinese | MEDLINE | ID: mdl-33982496

ABSTRACT

Nitrogen fertilizer has been the long-lasting crucial component in cultivation of Chinese materia medica(CMM) and crops for its profound effects on enhancing the productivity. In consideration of its role in better production, intensive and excessive application of N fertilizer is often found in CMM cultivation. Therefore, firstly, this review summarized various concentrations of N application with regards to different CMM and districts from the literatures published in the last two decades. The recommended concentration of nitrogen application of forty seven CMM species were covered in this review. We found that the optimum rates of nitrogen fertili-zer for different medicinal plants species were varied in the range between 0-1 035.55 kg·hm~(-2). Most of the optimum rates of nitrogen fertilizer for CMM in published researches fell between 100-199 kg·hm~(-2). The optimum rate of nitrogen fertilizer is not only related to amount of nitrogen required for different medicinal plants but also to soil fertilities of different fields. In addition, we outlined the diffe-rent effects of proper and excessive nitrogen deposition on yield of CMM. Proper nitrogen deposition benefits the yield of CMM, howe-ver, excessive nitrogen use accounts for a decrease in CMM yield. We elucidated that nutritional content, water use efficiencies, and photosynthesis capacity were major influencing factors. Researches showed that proper nitrogen fertilizer could promote the water use efficiencies of plants and boost photosynthesis. Consequently, the yield of CMM can be enhanced after nitrogen deposition. However, negative effects of nitrogen fertilizer were also found on plant including producing toxic substances to the soil and causing severe pest damages. Lastly we analyzed the impact of N fertilizer application on secondary metabolites which accounts for a large part of active pharmaceutical ingredients of CMM. It usually caused an increase in nitrogen-containing secondary metabolites content and a decrease in non-nitrogen-containing secondary metabolites content respectively. The potential underlying mechanisms are the different synthetic pathways of these metabolites and the plant nutritional status. Synthesis of non-nitrogen-containing secondary metabolites like phenols can be inhibited after nitrogen application because of the competition of the same precursor substances between metabolites synthesis and plant growth. To sum up, impacts and mechanisms of nitrogen fertilizer on yield and quality enhancement of CMM were discussed in this review. Negative effects of excessive nitrogen application on CMM should be paid special attention in CMM cultivation and prescription fertilization based on the field soil quality is strongly recommended. Overall, this review aims to provides insights on improving the proper application of N fertilizer in the cultivation of CMM.


Subject(s)
Materia Medica , Nitrogen , Agriculture , China , Fertilizers , Nitrogen/analysis , Soil
16.
Zhongguo Zhong Yao Za Zhi ; 46(8): 1893-1900, 2021 Apr.
Article in Chinese | MEDLINE | ID: mdl-33982497

ABSTRACT

Nitrogen is one of the most frequently used fertilizers in growth of Chinese medicinal plants(CMP). As in many other ecosystems, CMP ecosystem is also composed of plant-herbivore-natural enemy(tritrophic) interactions. Nitrogen fertilizer influences the growth and reproduction of CMP, and it is also able to heavily shape the ecosystem functions of CMP ecosystem through bottom-up forces. Understanding the specific effects of nitrogen fertilizer towards each trophic level will be beneficial to improve the resistance of CMP to herbivore and enhance the control efficiency of nature enemies to herbivore, and eventually, maximize the yield and quality of CMP. Most papers published on nitrogen use in plants focused mainly on the impact of nitrogen fertilization on CMP yield and quality. Influences of nitrogen application on CMP ecosystem get little attention at present. Therefore, this review summed up the potential effects of nitrogen fertilization on CMP ecosystem from perspectives of soil and tritrophic interactions. First of all, nitrogen fertilizer might decrease soil microbial biomass and altered the community structures of soil bacteria, fungi and protozoa. Negative effects of nitrogen fertilizer were found on biodiversity of soil bacteria and protozoa. Different fungi species respond differently to nitrogen fertili-zers. Nitrogen deposition can also decrease the soil pH. Decreases in soil microbial diversity and soil acidification can cause negative effects on CMP growth. In addition, nitrogen fertilizer could regulate the pest resistance of CMP including constitutive and inducible resistance. Both positive and negative effects of nitrogen application were found on pest resistance of CMP. Moreover, the development and predation of natural enemies were influenced by nitrogen deposition. Nitrogen influences natural enemies in many ways including plant volatiles, plant nutrient and structure and the supplementary food quality. Nectar and honeydew of plants and preys serve as important food source for natural enemies especially in early season when preys are still not available. Finally, the interactions between herbivores and their natural enemies were also shaped by nitrogen fertilizer in many aspects like increasing the nutritional content of prey and changing control efficiency of natural enemies. Some herbivores have evolved a strategy to sequester secondary metabolites which they absorbed from plant during their feeding. Studies showed that sequestration efficiency of secondary metabolites in prey could also be regulated by nitrogen. Parasitic, emergence, reproduction rate and longevity of parasites were found positively correlated with nitrogen deposition. Hopefully this study will shed light on practicable and economical application of nitrogen in cultivation of CMP.


Subject(s)
Ecosystem , Plants, Medicinal , China , Fertilizers , Nitrogen , Soil
17.
Zhongguo Zhong Yao Za Zhi ; 46(8): 1901-1909, 2021 Apr.
Article in Chinese | MEDLINE | ID: mdl-33982498

ABSTRACT

Nitrogen fertilizers play an important role in the regulation of plant stress resistance. Impacts of nitrogen fertilizers on abiotic stress resistance and biotic stress resistance of Chinese materia medica(CMM) were summarized in this study. Adequate nitrogen application improves the abiotic stress resistance and weed resistance of CMM, however adverse effect appears when excess nitrogen is used. Generally, pest resistance decreases along with nitrogen deposition, while effects of nitrogen application on disease resistance vary with different diseases. Mechanisms underlying the impact of nitrogen fertilizers on plant stress resistance were also elucidated in this study from three aspects including physical defense mechanisms, biochemistry mechanisms and molecular defense mechanisms. Nitrogen availability modulates physical barrier of CMM like plant growth, formation of lignin and wax cuticle, and density of stomata. Growth of CMM promoted by nitrogen fertilizer may cause some decrease in pest resistance of CMM due to an increase in hiding places for pest along with plant growth. High ambient humidity caused by excessive plant growth facilitates the growth and development of CMM pathogen. Nitrogen application can also interfere with the accumulation of lignin in CMM which makes CMM more vulnerable to pest and pathogen attack. Stomatal closing delays due to nitrogen application is also a causal factor of increasing pathogen infection after nitrogen deposition. Biochemical defenses of plants are mainly achieved through nutrient elements, secondary metabolites, defense-related enzymes and proteins. Nutritional level of CMM and various antioxidant enzymes and resistance-related protein activities are elevated along with nitrogen deposition. These antioxidant enzymes can reduce the damage of reactive oxygen species content produced by plant in response to adversity and therefore enhance stress resistance of CMM. Researches showed that nitrogen application could also cause an increase in nitrogen-containing secondary metabolites content and a decrease in non-nitrogen-containing secondary metabolites content respectively. Nitrogen-mediated molecular defense mechanisms includes multiple plant hormones and nitric oxide signals. Plant hormones related to plant defense like salicylic acid, jasmonic acid and abscisic acid can be modulated by nitrogen application. Negative effect of nitrogen deposition was found on salicylic acid accumulation and the expression of related plant disease resistance genes. However, jasmonic acid level can be elevated by nitrogen. Nitric oxide signals constitute an important part of nitrogen mediated defense mechanisms. Nitric oxide signaling is related to many aspects of plant immunity. The roles of nitrogen fertilizers in CMM stress resistance are complex and may vary with different CMM varieties and environments. Further studies are urgently needed to provide a comprehensive understanding of how to improve stress resistance of CMM by using fertilizers.


Subject(s)
Materia Medica , Abscisic Acid , China , Nitrogen , Plant Growth Regulators
18.
Zhongguo Zhong Yao Za Zhi ; 46(8): 1927-1934, 2021 Apr.
Article in Chinese | MEDLINE | ID: mdl-33982501

ABSTRACT

The study is aimed through field experiments to study the effect of combined application of organic and chemical fertilizers on the growth and quality of Salvia miltiorrhiza, provide ideas for reducing fertilization while increasing the efficiency as well as improving the quality of produces. The experiment included 6 treatments viz., no fertilization(CK), full application of chemical fertilizer(F), 25% orga-nic fertilizer with 75% chemical fertilizer(M25), 50% organic fertilizer with 50% chemical fertilizer(M50), 75% organic fertilizer with 25% chemical fertilizer(M75), and fully apply organic fertilizer(M100). The results showed that:(1)from the perspective of yield and economic benefits, M75 was the best and M100 second;(2)for effective components, the combined application of organic and chemical fertilizers increased the content of main water-soluble components and the total content of effective components, among which M25 and M50 were better.


Subject(s)
Fertilizers , Salvia miltiorrhiza , Agriculture , Fertilizers/analysis , Nitrogen , Soil
19.
IEEE Trans Cybern ; 51(6): 3348-3360, 2021 Jun.
Article in English | MEDLINE | ID: mdl-31449039

ABSTRACT

The local community detection is a significant branch of the community detection problems. It aims at finding the local community to which a given starting node belongs. The local community detection plays an important role in analyzing the complex networks and recently has drawn much attention from the researchers. In the past few years, several local community detection algorithms have been proposed. However, the previous methods only make use of the limited local information of networks but overlook the other valuable information. In this article, we propose an evolutionary computation-based algorithm called evolutionary-based local community detection (ELCD) algorithm to detect local communities in the complex networks by taking advantages of the entire obtained information. The performance of the proposed algorithm is evaluated on both synthetic and real-world benchmark networks. The experimental results show that the proposed algorithm has a superior performance compared with the state-of-the-art local community detection methods. Furthermore, we test the proposed algorithm on incomplete real-world networks to show its effectiveness on the networks whose global information cannot be obtained.

20.
ACS Appl Bio Mater ; 4(10): 7587-7594, 2021 10 18.
Article in English | MEDLINE | ID: mdl-35006694

ABSTRACT

In this work, the photocatalytic and photothermal effects of carbon-ring-doped graphitic carbon nitride materials against bacteria were systematically studied in a dispersed solution and on a membrane. C-doped graphitic carbon nitride materials C-CN 0.15, 1.5, and 7.5 were synthesized by mixing urea precursor with 0.15, 1.5, and 7.5 wt % glucose. With the increase in the doping level, the photothermal effect was clearly enhanced while the generation of reactive oxygen species (ROS) was slightly inhibited. With exposure to irradiation under a 100 mW cm-2 Xeon lamp with a cutoff filter (λ ≥ 420 nm), the ROS concentration of C-CN 1.5 increased 30% in the dispersed solution and its temperature increased about 10 °C in the dispersed solution and on the membrane compared to that of pristine carbon nitride. As a result, the bactericidal activity of C-CN 1.5 was improved by an order of magnitude in the dispersed solution and more than 2 orders of magnitude on the membrane immersed in a solution at 40 °C. To investigate the fundamental light absorption process on the membrane, an optical model using the finite-difference time-domain method was developed based on the topography of the membrane. The simulation results may explain that although C-CN produces more ROS in a solution; however, with a larger extinction coefficient, the power absorption is lower near the surface of the membrane. The ROS production is therefore inhibited and the bactericidal activity is dominated by the photothermal effect. Our experimental and simulation results provide a basis for designing high-performance photoactive disinfection materials and surfaces.


Subject(s)
Disinfection , Light , Bacteria , Disinfection/methods , Graphite , Nitrogen Compounds , Reactive Oxygen Species
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