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Afr Health Sci ; 19(4): 3208-3216, 2019 Dec.
Article in English | MEDLINE | ID: mdl-32127898

ABSTRACT

BACKGROUND: Helicobacter pylori frequently causes gastritis and peptic ulcers, and affected children are at risk of developing gastric carcinoma later in adulthood. METHODS: This was a Hospital based cross sectional study. A total of 200 children aged 6 months to 14 years were enrolled. Study subjects were tested for H. pylori using a standard serology rapid test measuring immunoglobulin G for H. pylori. For risk factors, Chi-square tests were used to test for association and then, odds ratios and their corresponding 95% confidence intervals and p-values were computed using logistic regression. RESULTS: The overall seroprevalence of H. pylori was 11.5%. The following factors were associated with H. pylori infection: Age group above 10 years, keeping a dog and household size. The independent predictors of H. pylori were: Fathers' occupation, keeping a dog, indoor tap water, age group, household size and diabetes mellitus type 1.. CONCLUSION: The seroprevalence of H. pylori antibodies was lower compared to most developing countries. Keeping a dog, household size, indoor tap water, fathers' occupation and diabetes mellitus type 1 were found to be independent predictors of presence of H. pylori antibodies.


Subject(s)
Antibodies, Bacterial/blood , Comorbidity , Helicobacter Infections/complications , Helicobacter Infections/epidemiology , Helicobacter Infections/immunology , Adolescent , Age Factors , Child , Child, Preschool , Cross-Sectional Studies , Female , Humans , Infant , Logistic Models , Male , Odds Ratio , Risk Factors , Seroepidemiologic Studies , Tanzania/epidemiology
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