ABSTRACT
AIMS: This study aimed to quantify the degrees of movement that occur in the lower limb using a kinematic system after taking two measurements of 45° and 60° of extension at the first metatarsophalangeal joint (1st MTPJ) and to test the validity of this sensor system using radiography. METHODOLOGY: This was a quasi-experimental test-post-test study with a single intervention group (25 subjects). Four inertial sensors were placed on the proximal phalange of the first toe, dorsum of the foot, medial-lateral of the leg (level of tibia), and medial-lateral of the thigh (level of femur). The extension of the 1st MTPJ produced movements of supination in the foot and rotation at the level of leg and thigh. We studied this mechanism in three situations (relaxed, 45°, and 60°) both with the sensors and with X-rays. RESULTS: With the kinematic system, there was an increase in the range of movement in each of the variables, with a value of p < 0.05. The relationship between the kinematic system and the radiography was tested using Spearman's rho test, obtaining a correlation coefficient of 0.624 and a value of p < 0.05, and the Bland-Altman graph, with 90% of the cases within the tolerance limits. CONCLUSIONS: The extension of the 1st MTPJ generated kinematic changes associated with supination movement in the midfoot and external rotation on the tibia and femur level. Both measurement techniques were very similar in the way that they quantified the degrees of extension of the 1st MTPJ. If we extrapolate this result to the measurement technique used by the inertial sensors, we could affirm that the values recorded in the supination and external rotation movements were reliable.
Subject(s)
Lower Extremity , Tibia , Humans , Range of Motion, Articular , Femur , MovementABSTRACT
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Subject(s)
Humans , Male , Child , Fasciitis, Necrotizing/diagnosis , Talipes Cavus/surgery , Emergency Treatment/methods , Postoperative Complications/diagnosis , Fasciitis, Necrotizing/surgery , Lower Extremity/diagnostic imagingABSTRACT
BACKGROUND: Taking a mold of the foot is an important advance for podiatric medicine and an indispensable procedure for the individualization of orthopedic treatments. We sought to determine which method of measuring molds (plaster cast in weightbearing and nonweightbearing and phenolic foam in weightbearing) reproduces with more reliability the expansion of the foot in weightbearing by comparing the widths of the forefoot and hindfoot in the different methods and in barefoot weightbearing. METHODS: In 54 patients, we studied the differences in width between the forefoot and hindfoot in barefoot weightbearing compared with in the different mold obtainment techniques. A descriptive, observational, and transversal study was performed in which foot molds were obtained with the different techniques, without corrective maneuvers, followed by scanning of each as well as barefoot weightbearing. RESULTS: Significant differences among the techniques were shown, with phenolic foam being more similar to barefoot weightbearing in forefoot and hindfoot width. CONCLUSIONS: The method that reproduces the expansion of the foot in weightbearing with more reliability is phenolic foam. The forefoot width is superior in barefoot weightbearing versus the three foot casts studied. The hindfoot width is superior in the foot cast with plaster in weightbearing compared with barefoot weightbearing and the other two foot casts.
ABSTRACT
BACKGROUND: The windlass mechanism was described as the effect caused by the extension of the first metatarsalphalangeal joint (1st MTPJ). Quantify the degrees of movement produced in the leg by means of the Bioval® sensor system, after performing two measurements in the 1st MTPJ, 45° extension and maximum extension. METHODS: Tests-post-test study with just one intervention group, performed in the Clinical Podiatry Area of the Faculty of Nursing, Physiotherapy and Podiatry of the University of Seville. Subjects were included as of age 20, with a value from 0° to 3° valgus, Helbing line, a value from 0° to +5° for the foot postural index, and a localisation axis for the normalised subtalar joint. Subjects with surgical operations of the first ray, fractures and surgical operations in the leg, pathologies in the first ray and rheumatic diseases were excluded. Measurement was performed with the Bioval® system by means of inserting four sensors in the bone structures involved in the windlass mechanism. RESULTS: With the 45° wedge we observed a direct correlation among the variables extension-plantar flexion 1st MTPJ and rotation of the femur. With maximal extension of the 1st MTPJ we obtained a direct relationship between the variable extension of the 1st MTPJ and the variables plantar flexion and prono-supination of the 1st metatarsal as well as with the variables tibia rotation and femur rotation. CONCLUSION: Kinematic analysis suggested that the higher the degree of extension the more movement will be generated. This reduces the level of impact the more distal the structure with respect to the 1st MTPJ, which has an impact on the entire leg. Because of the kinematic system used wasn't suitable, its impact wasn't exactly quantified.
ABSTRACT
Objetivo El objetivo de este estudio fue evaluar si la determinación de RNA del virus de la hepatitis C (VHC-RNA) a las 12 semanas tras la finalización del tratamiento podía predecir la respuesta viral sostenida al tratamiento anti-VHC (interferón pegilado alfa-2a y ribavirina) en enfermos coinfectados por el virus de la inmunodeficiencia humana (VIH).Enfermos y métodos Fueron incluidos los pacientes coinfectados por VIH y VHC que completaron un curso completo de tratamiento anti-VHC y que fueron evaluados a las semanas +12 y +24 tras la finalización del tratamiento para determinación del HCV-RNA sérico (RealTime HCV (Abbott, Wiesbaden, Alemania) (límite inferior de detección, 12 U/ml).Resultados Cuarenta de los 66 enfermos tratados (61%) presentaron una respuesta al final del tratamiento. Se les realizó una valoración a las 12 y 24 semanas tras el fin de la terapia. El VHC-RNA sérico fue indetectable en 28 de ellos a la semana +12, y el 100% de ellos permaneció indetectable a la semana +24 (el patrón de referencia de respuesta viral sostenida). El valor predictivo positivo fue 100% (intervalo de confianza al 95% 98,21-100%).Conclusión La evaluación posterior al tratamiento de la hepatitis crónica C en enfermos coinfectados por VIH para detectar la presencia de recaída virológica puede ser realizada a la semana +12, en lugar de a la semana +24, proporcionando así una nueva definición de respuesta virológica sostenida (AU)
Objective The aim of this study was to assess whether measurement of hepatitis C virus RNA (HCV-RNA) at 12 weeks post-treatment could predict sustained virological response (SVR) to antiviral therapy for chronic hepatitis C (pegylated interferon alfa-2a and ribavirin) in HIV-co-infected patients. Patients and methods HIV-HCV co-infected patients were included if they completed a full course of anti-HCV therapy, achieved an end-of-treatment response and complied with the week +12 and +24 post-treatment follow-up schedule for serum HCV-RNA determination (Real-time HCV (Abbott, Wiesbaden, Germany) (lower limit of detection, 12 IU/ml).Results Forty out of 66 patients (61%) showed an end-of-treatment response. They were assessed in a follow-up visit at +12 and at +24 weeks post-treatment. Serum HCV-RNA was undetectable in 28 of them at +12 weeks, and 100% of these remained undetectable at 24 weeks post-treatment (the gold standard of (SVR). The positive predictive value was 100% (95% confidence interval, 98.21-100%).Conclusion Post-treatment follow-up to identify virological relapse could be shortened to 12 weeks, providing a new definition of sustained virological response (AU)
Subject(s)
Humans , RNA, Viral/analysis , Hepacivirus/pathogenicity , Hepatitis C, Chronic/microbiology , Hepatitis C, Chronic/complications , HIV Infections/complications , Interferons/therapeutic use , Viral Load , Ribavirin/therapeutic useABSTRACT
OBJECTIVE: The aim of this study was to assess whether measurement of hepatitis C virus RNA (HCV-RNA) at 12 weeks post-treatment could predict sustained virological response (SVR) to antiviral therapy for chronic hepatitis C (pegylated interferon alfa-2a and ribavirin) in HIV-co-infected patients. PATIENTS AND METHODS: HIV-HCV co-infected patients were included if they completed a full course of anti-HCV therapy, achieved an end-of-treatment response and complied with the week +12 and +24 post-treatment follow-up schedule for serum HCV-RNA determination (Real-time HCV (Abbott, Wiesbaden, Germany) (lower limit of detection, 12 IU/ml). RESULTS: Forty out of 66 patients (61%) showed an end-of-treatment response. They were assessed in a follow-up visit at +12 and at +24 weeks post-treatment. Serum HCV-RNA was undetectable in 28 of them at +12 weeks, and 100% of these remained undetectable at 24 weeks post-treatment (the gold standard of (SVR). The positive predictive value was 100% (95% confidence interval, 98.21-100%). CONCLUSION: Post-treatment follow-up to identify virological relapse could be shortened to 12 weeks, providing a new definition of sustained virological response.
