ABSTRACT
Polypoidal choroidal vasculopathy (PCV) is a disease that was first described almost 30 years ago. The disease is characterised by alterations of the posterior pole such as serous or serosanguineous detachments of the retina or the retinal pigment epithelium (RPE) around the optic nerve or in the central macula. The optimal therapeutic regime remains unclear. There are several studies suggesting that patients who do not respond satisfactorily to intravitreal anti-VEGF treatment are suffering from PCV which can be detected by indocyanine green angiography. Alternative therapeutic options consist of photodynamic therapy or laser photocoagulation for extrafoveal lesions.
Subject(s)
Angiogenesis Inhibitors/therapeutic use , Choroidal Neovascularization/diagnosis , Choroidal Neovascularization/therapy , Polyps/diagnosis , Polyps/therapy , Fluorescein Angiography/methods , Humans , Laser Therapy , Photochemotherapy , Vascular Endothelial Growth Factor A/antagonists & inhibitorsABSTRACT
Senile scleral plaques are characterized by a calcification located at the insertion of the horizontal rectus muscles. As a possible cause for their development a combination of solar tissue damage and continuous mechanical stress is discussed. We present a case of a 76-year-old male whose wife noticed expulsion of a calcified scleral plaque while applying antiglaucoma eyedrops. The local antiglaucoma therapy was stopped and acetacolamide was administered. Local therapy consisted of hyaluronic acid eyedrop and calcium pantothenate and retinol palmiate eye ointment. This treatment led to a rapid reepithelialization. The expulsion of calcified senile scleral plaques is a described complication which can necessitate surgical treatment.
Subject(s)
Calcinosis/chemically induced , Calcinosis/prevention & control , Eye Foreign Bodies/chemically induced , Eye Foreign Bodies/prevention & control , Ophthalmic Solutions/adverse effects , Plaque, Amyloid/chemically induced , Plaque, Amyloid/prevention & control , Aged , Humans , Male , Treatment OutcomeABSTRACT
Systemic lupus erythematosus (SLE) is a chronic, relapsing and remitting autoimmune disease of unknown etiology. As in other rheumatic diseases sicca syndrome is often present. Additionally retinal vascular pathologies such as cotton wool spots and intraretinal hemorrhages are present in 7-8% of patients with SLE. SLE-related retinal vascular pathologies are activity markers and a prognostic factor for poor outcome. The case of a 38-year-old patient is reported with decompensated SLE who presented in our clinic with floaters and flickering scotoma but good visual acuity. Funduscopy and fluorescence angiography revealed bilateral choroidal vessel occlusions. Additionally, a hemorrhagic choroidal infarction and a preretinal hemorrhage were detected in the right eye. In summary SLE can result in choroidal vasoocclusion especially if decompensated arterial hypertension is present.
