ABSTRACT
El penfigoide ampolloso es una enfermedad que característicamente afecta a personas de edad avanzada aunque se han descrito casos en niños. Presentamos un caso de penfigoide ampolloso en una lactante de 2 meses de vida con lesiones ampollosas en palmas y plantas, que aparecieron una semana después de recibir la primera dosis de la vacuna contra la hepatitis B, poliomielitis, difteria-tétanos-pertussis (DTP) y Haemophilus. Recibió tratamiento con agua sulfatada, dexametasona y ácido fusídico, con lo que desaparecieron las lesiones. Un mes después presentó un nuevo brote, más generalizado, a los 3 días de la segunda dosis de la misma vacuna. La erupción cutánea cedió por completo a los 3 meses de instaurar tratamiento con deflazacort (1 mg/kg/día). Tras 5 años de seguimiento, no ha vuelto a presentar lesiones a pesar de haber recibido el resto de vacunas del calendario oficial
Bullous pemphigoid (BP) is a disease that characteristically affects the elderly, although cases have been described in children. We present a case of BP in a twomonth- old infant with bullous lesions on the palms and soles, which appeared one week after receiving the first dose of the hepatitis B, polio, DTP and HiB vaccine. She was treated with sulphated water, dexamethasone and fusidic acid, and the lesions disappeared. One month later, she presented with a new, more generalized outbreak, three days after the second dose of the same vaccine. The skin eruption completely subsided 3 months after treatment with deflazacort was initiated (1 mg/kg/day). After five years of follow up, the patient has not presented with lesions again, despite having received the rest of the vaccines on the official schedule
Subject(s)
Female , Infant , Humans , Pemphigoid, Bullous/diagnosis , Pemphigoid, Bullous/therapy , Vaccines/adverse effects , Viral Hepatitis Vaccines/adverse effects , Poliovirus Vaccine, Inactivated/adverse effects , Diphtheria-Tetanus-Pertussis Vaccine/adverse effects , Hepatitis B/immunology , Poliomyelitis/immunology , Diphtheria/immunology , Haemophilus/immunology , Haemophilus/isolation & purification , Vaccination/adverse effectsABSTRACT
Bullous pemphigoid (BP) is a disease that characteristically affects the elderly, although cases have been described in children. We present a case of BP in a two-month-old infant with bullous lesions on the palms and soles, which appeared one week after receiving the first dose of the hepatitis B, polio, DTP and HiB vaccine. She was treated with sulphated water, dexamethasone and fusidic acid, and the lesions disappeared. One month later, she presented with a new, more generalized outbreak, three days after the second dose of the same vaccine. The skin eruption completely subsided 3 months after treatment with deflazacort was initiated (1 mg/kg/day). After five years of follow up, the patient has not presented with lesions again, despite having received the rest of the vaccines on the official schedule.
