ABSTRACT
OBJECTIVE: Calprotectin is a biomarker of gastrointestinal inflammation and disease activity. We aimed to evaluate the performance of a new fecal calprotectin (FC) test (CALiaGold®) in comparison with two other rapid FC immunoassays. METHODS: Fecal samples were analyzed with all three FC tests. Correlation between the FC tests was assessed. Agreement to discriminate FC-positive samples was also evaluated according to the manufacturers' cut-off values. RESULTS: A correlation coefficient of over 0.800 was found in all comparisons. Lower deviation of linearity was observed between immunoturbidimetric assays. Agreement on FC-positive sample detection was reduced in comparisons with the immunochromatographic assay. CONCLUSIONS: The CALiaGold® test showed good performance for FC assessment. Better correlation and agreement between immunoturbidimetric assays were confirmed.
