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1.
Res Exp Med (Berl) ; 174(1): 67-78, 1978 Dec 27.
Article in German | MEDLINE | ID: mdl-734246

ABSTRACT

In the atrioventricular system (AVS) consisting of the compact node, the penetrating bundle and the branching bundles of about 250 bovine hearts there were made several studies: 1. In quickly removed and fixed specimens (distal AV-node, penetrating bundle) determination of a metabolic state with respect to glycogen, glucose, lactate, ATP, ADP, AMP, creatinephosphate, total creatine, gluc-6-phosphate, fructose-6-phosphate, fructose-1,6-diphosphate, dihydroxyacetonphosphate and pyruvate. 2. Determination of glycogen contents and glygolytic activity in AVS and its parts for ischemic times up to three hours. 3. The determination of metabolic contents in samples of connective tissue in atrium and ventricle of bovine hearts. The AV-nodes are poor in glycogen comparable with glycogen content of central nervous system and other ganglia. Penetrating bundles of Hiss and branching bundle belong after liver to the glycogen richest parenchyma of animal tissues. Even after ischemia of 3 h only a part of glycogen was recovered as lactate. The greater part of glycogen must be considered as a structural element of Hiss bundle and branching bundles of the ventricles.


Subject(s)
Glycogen/analysis , Heart Conduction System/analysis , Adenosine Diphosphate/analysis , Adenosine Monophosphate/analysis , Adenosine Triphosphate/analysis , Animals , Cattle , Connective Tissue/analysis , Creatine/analysis , Dihydroxyacetone Phosphate/analysis , Fructosephosphates/analysis , Glucose/analysis , Glucosephosphates/analysis , Glycolysis , Ischemia , Lactates/analysis , Pyruvates/analysis
2.
Arch Gynakol ; 221(3): 203-10, 1976 Oct 15.
Article in German | MEDLINE | ID: mdl-990063

ABSTRACT

Plasma polyps can be found at the end of a normal pregnancy. Following NaF and MJA-intoxication, there is an extreme increase of plasma polyps. This accelerated formation can be prevented by the injection of Na-pyruvate and often the number of polyps can be reduced below the norm. 2,4-Dinitrophenol intoxication and breathing of hypoxic gas mixture (2,5% O2, 5% CO2, 92,5% N2) do not lead to increased plasma polyp formation. This proves, that it is not hypoxia, not an energy deficit secondary to separation of oxydative phosphorylation and not cardiac insufficiency leading to secondary ischemia which are responsible for the extreme increase in the number of plasma polyps following the injection of MJA and NaF.


Subject(s)
Acetates/pharmacology , Dinitrophenols/pharmacology , Fluorides/pharmacology , Hypoxia/pathology , Placenta/drug effects , Animals , Female , Guinea Pigs , Placenta Diseases/chemically induced , Polyps/etiology , Pregnancy , Pyruvates/pharmacology
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