ABSTRACT
Growing evidence for global pollinator decline is causing concern for biodiversity conservation and ecosystem services maintenance. Neonicotinoid pesticides have been identified or suspected as a key factor responsible for this decline. We assessed the global exposure of pollinators to neonicotinoids by analyzing 198 honey samples from across the world. We found at least one of five tested compounds (acetamiprid, clothianidin, imidacloprid, thiacloprid, and thiamethoxam) in 75% of all samples, 45% of samples contained two or more of these compounds, and 10% contained four or five. Our results confirm the exposure of bees to neonicotinoids in their food throughout the world. The coexistence of neonicotinoids and other pesticides may increase harm to pollinators. However, the concentrations detected are below the maximum residue level authorized for human consumption (average ± standard error for positive samples: 1.8 ± 0.56 nanograms per gram).
Subject(s)
Bees/drug effects , Bees/physiology , Food Contamination , Honey/analysis , Insecticides/analysis , Neonicotinoids/analysis , Animals , Biodiversity , Guanidines/analysis , Guanidines/toxicity , Insecticides/toxicity , Neonicotinoids/toxicity , Nitro Compounds/analysis , Nitro Compounds/toxicity , Oxazines/analysis , Oxazines/toxicity , Pollination , Thiamethoxam , Thiazines/analysis , Thiazines/toxicity , Thiazoles/analysis , Thiazoles/toxicityABSTRACT
The experience in consecutive procedures with 800 recanalization attempts of chronic total coronary occlusions using the Magnum wire was analyzed from a prospectively constituted computerized database. The data confirm that the Magnum wire, generally used as a primary intervention for occlusive angioplasty at our centers, is competitive with conventional systems in this setting.
Subject(s)
Angioplasty, Balloon, Coronary/instrumentation , Coronary Disease/therapy , Coronary Angiography , Female , Humans , Male , Middle Aged , Retrospective Studies , Treatment OutcomeABSTRACT
The magnum wire is a stiff-shaft, blunt-tip wire constructed for recanalisation during angioplasty. Smaller series have demonstrated superior qualities compared to conventional wires. The purpose of this study was to analyze its feasibility in a larger number of procedures. A single centre database analysis identified the use of Magnum wire during 443 procedures accounting for 26% of all angioplasties from October 1992 to February 1995. There were 347 total occlusions and 222 non-total lesions. Technical success was 69% in total and 90% in non-total lesions, whereas angiographic success was 58% and 75%, respectively. Stents were successfully implanted in 48 lesions; in 29 (8%) total occlusions and 19 (9%) non-total lesions. The total occlusion-related complication rate was 1.7%. Acute closure occurred in 4.1% of non-total lesions. In conclusion, Magnum wire is a feasible tool for angioplasty of total occlusions and severe stenoses. It is a cheap, simple and safe method for recanalisation.
