1.
Chem Commun (Camb)
; 58(90): 12560-12563, 2022 Nov 10.
Article
in English
| MEDLINE
| ID: mdl-36264220
ABSTRACT
Amine-containing natural products are an important class of therapeutic compounds. Herein, we report a chemoselective approach to catch and enrich amine-containing natural products, and release them as underivatized compounds. The strategy exploits the selectivity of the enzyme legumain for the specific release of amine-containing natural products.