ABSTRACT
CASE REPORT: We report the case of a 76-year-old woman who attended our hospital because of a sudden loss of visual acuity in her left eye. The problem appeared to be that of retrobulbar optic neuritis. However, the age of the patient together with the simultaneous use of Infliximab to treat her rheumatoid arthritis, suggests the demyelination may have been associated with the Infliximab use. DISCUSSION: TNFa inhibitors (including Infliximab) are associated with demyelinating diseases including optic neuritis.
Subject(s)
Antibodies, Monoclonal/adverse effects , Antirheumatic Agents/adverse effects , Optic Neuritis/chemically induced , Aged , Female , Humans , InfliximabABSTRACT
Caso clínico: Se describe el caso de una paciente de 76 años de edad que presenta una disminución brusca de la agudeza visual en su ojo izquierdo. El cuadro es compatible con una neuritis óptica retrobulbar que en el contexto de una paciente de esta edad y en tratamiento con Infliximab por una artritis reumatoide sugiere la posibilidad de que se trate de una desmielinización asociada al tratamiento con Infliximab. Discusión: Los inhibidores del TNFα (entre ellos el Infliximab) pueden dar lugar a eventos desmielinizantes entre los cuales puede encontrarse una neuritis óptica retrobulbar
Case report: We report the case of a 76-year-old woman who attended our hospital because of a sudden loss of visual acuity in her left eye. The problem appeared to be that of retrobulbar optic neuritis. However, the age of the patient together with the simultaneous use of Infliximab to treat her rheumatoid arthritis, suggests the demyelination may have been associated with the Infliximab use. Discussion: TNFα inhibitors (including Infliximab) are associated with demyelinating diseases including optic neuritis
Subject(s)
Female , Aged , Humans , Optic Neuritis/chemically induced , Tumor Necrosis Factor-alpha/adverse effects , Arthritis, Rheumatoid/drug therapy , Visual AcuityABSTRACT
Deficient mydriasis of diverse etiology renders extracapsular cataract extraction and posterior chamber intraocular lens implantation technically difficult. Several techniques are available to improve surgical results when this problem is present. We have used multiple sphincterotomies in 6 patients with narrow pupils undergoing cataract extraction. We discuss the indications, intraoperative complications and postoperatory evolution of these cases.
Subject(s)
Cataract Extraction/methods , Iris/pathology , Adult , Aged , Aged, 80 and over , Humans , Middle AgedABSTRACT
Deficient mydriasis of diverse etiology renders extracapsular cataract extraction and posterior chamber intraocular lens implantation technically difficult. Several techniques are available to improve surgical results when this problem is present. We have used multiple sphincterotomies in 6 patients with narrow pupils undergoing cataract extraction. We discuss the indications, intraoperative complications and postoperatory evolution of these cases
