ABSTRACT
15 patients with lung carcinoma associated with cardiovascular involvement were treated surgically. Of these patients, 2 had involvement of the heart, 3 the superior vena cava, and 10 the pulmonary artery. Patient selection, operation forms, techniques, complications, and operation-made metastasis were discussed.
Subject(s)
Carcinoma, Squamous Cell/pathology , Lung Neoplasms/pathology , Lung Neoplasms/surgery , Aged , Carcinoma, Squamous Cell/surgery , Female , Heart Neoplasms/pathology , Humans , Male , Middle Aged , Neoplasm Invasiveness , Pulmonary Artery/pathology , Pulmonary Artery/surgery , Vascular Surgical Procedures/methods , Vena Cava, Superior/pathology , Vena Cava, Superior/surgeryABSTRACT
Eighteen operations on 16 patients with tracheal tumors were reported. Of these cases, 11 had primary tracheal tumors and 6 had secondary ones. The tumors were malignant in 10, low malignancy in 3, and benign in the remaining 3 cases. The diagnostic procedure, operative technique, and management of postoperative complications are discussed.
Subject(s)
Tracheal Neoplasms/surgery , Adenocarcinoma/secondary , Adenocarcinoma/surgery , Adult , Carcinoma, Adenoid Cystic/surgery , Carcinoma, Papillary/surgery , Female , Humans , Male , Middle Aged , Thyroid Neoplasms , Tracheal Neoplasms/secondary , Tracheotomy/methodsABSTRACT
ZnSO4 3-5 mg/kg iv decreased systolic blood pressure, diastolic blood pressure and mean arterial blood pressure, +dP/dtmax, -dP/dtmax, VCE- +dP/dtmax, and left ventricular systolic pressure. However, ZnSO4 had no significant effects on T values and total peripheral resistance. In addition, ZnSO4 obviously decreased heart rate and cardiac index. These results suggest that iv ZnSO4 may cause hypotension via cardiac inhibition.
Subject(s)
Hemodynamics/drug effects , Sulfates/pharmacology , Zinc/pharmacology , Animals , Blood Pressure/drug effects , Dogs , Guinea Pigs , Heart Function Tests , Myocardial Contraction/drug effects , Zinc SulfateABSTRACT
The effects of dicarboxyethenylgermanium sesquioxide (DCG) on electrical and mechanical activity in isolated guinea pig papillary muscles and rabbit sinus node were studied by intracellular capillary glass electrode. The effects of DCG on slow action potential and contractile force (Fc) of preparations in which the fast Na+ channels were inactive by partial depolarization by increasing the concentration of K+ 25.4 mmol/L were observed. DCG (0.5 mol/L) increased Vmax and APA of fast action potential of guinea pig papillary muscles, but its Fc decreased from 105 +/- 12% of control to 80 +/- 16%. DCG prolonged the spontaneous cycle length (SCL) and APD90 of rabbit sinus node, but the slope of phase 4(SP4) was lowered. The functional refractory period (FRP) of rabbit left atria was determined by the paired stimulus method. In experiments involving one drug, the drug was added until equilibrium had been reached. It has been demonstrated by experiments that the administration of DCG resulted in an increase of atrial FRP. These findings suggest that the Ca2+ inward currents and the K+ outward current may be inhibited by DCG.
