Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 6 de 6
Filter
Add more filters











Database
Publication year range
1.
Sci Total Environ ; 941: 173557, 2024 Sep 01.
Article in English | MEDLINE | ID: mdl-38806128

ABSTRACT

Despite the success of the growing data-driven landslide susceptibility prediction, the model training heavily relies on the quality of the data (involving topography, geology, hydrology, land cover, climate, and human activity), the structure of the model, and the fine-tuning of the model parameters. Few data-driven methods have considered incorporating 'landslide priors', as in this article the prior knowledge or statistics related to landslide occurrence, to enhance the model's perception in landslide mechanism. The main objective and contribution of this study is the coupling of landslide priors and a deep learning model to improve the model's transferability and stability. This is accomplished by selecting non-landslide sample grounded on landslide statistics, disentangling input landslide features using a variational autoencoder, and crafting a loss function with physical constraints. This study utilizes the SHAP method to interpret the deep learning model, aiding in the acquisition of feature permutation results to identify underlying landslide causes. The interpretation result indicates that 'slope' is the most influential factor. Considering the extreme rainfall impact on landslide occurrences in Hong Kong, we combine this prior into the deep learning model and find feature ranking for 'rainfall' improved, in comparison to the ranking result interpreted from a pure MLP. Further, the potency of MT-InSAR is utilized to augment the landslide susceptibility map and promote efficient cross-validation. A comparison of InSAR results with historical images reveals that detectable movement before their occurrence is evident in only a minority of landslides. Most landslides occur spontaneously, exhibiting no precursor motion. Comparing with other data-driven methods, the proposed methods outperform in accuracy (by 2 %-5 %), precision (by 2 %-7 %), recall (by 1 %-3 %), F1-score (by 8 %-10 %), and AuROC (by 2 %-4 %). Especially, the Cohen Kappa performance surpasses nearly 20 %, indicating that the knowledge-aware methodology enhances model generalization and mitigates training bias induced by unbalanced positive and negative samples.

2.
Natl Sci Rev ; 8(9): nwab123, 2021 Sep.
Article in English | MEDLINE | ID: mdl-34691745

ABSTRACT

By analysing the technical advantages and characteristics of imaging radar in cultural heritage, we provide new insights for the future development of cutting-edge Digital Heritage approaches through technical integration and interdisciplinary synergy.

3.
Cell Physiol Biochem ; 45(1): 119-130, 2018.
Article in English | MEDLINE | ID: mdl-29339630

ABSTRACT

BACKGROUND/AIMS: A network meta-analysis is used to compare the efficacy of ropinirole, rasagiline, rotigotine, entacapone, apomorphine, pramipexole, sumanirole, bromocriptine, piribedil and levodopa, with placebo as a control, for non-motor symptoms in Parkinson's disease (PD). METHODS: PubMed, Embase and the Cochrane Library were searched from their establishment dates up to January 2017 for randomized controlled trials (RCTs) investigating the efficacy of the above ten drugs on the non-motor symptoms of PD. A network meta-analysis combined the evidence from direct comparisons and indirect comparisons and evaluated the pooled weighted mean difference (WMD) values and surfaces under the cumulative ranking curves (SUCRA). The network meta-analysis included 21 RCTs. RESULTS: The analysis results indicated that, using the United Parkinson's Disease Rating Scale (UPDRS) III, the efficacies of placebo, ropinirole, rasagiline, rotigotine, entacapone, pramipexole, sumanirole and levodopa in treating PD were lower than that of apomorphine (WMD = -10.90, 95% CI = -16.12∼-5.48; WMD = -11.85, 95% CI = -17.31∼-6.16; WMD = -11.15, 95% CI = -16.64∼-5.04; WMD = -11.70, 95% CI = -16.98∼-5.60; WMD = -11.04, 95% CI = -16.97∼-5.34; WMD = -13.27, 95% CI = -19.22∼-7.40; WMD = -10.25, 95% CI = -15.66∼-4.32; and WMD = -11.60, 95% CI = -17.89∼-5.57, respectively). Treatment with ropinirole, rasagiline, rotigotine, entacapone, pramipexole, sumanirole, bromocriptine, piribedil or levodopa, with placebo as a control, on PD exhibited no significant differences on PD symptoms when the UPDRS II was used for evaluation. Moreover, using the UPDRS III, the SUCRA values indicated that a pomorphine had the best efficacy on the non-motor symptoms of PD (99.0%). Using the UPDRS II, the SUCRA values for ropinirole, rasagiline, rotigotine, entacapone, pramipexole, sumanirole, bromocriptine, piribedil and levodopa treatments, with placebo as a control, indicated that bromocriptine showed the best efficacy on the non-motor symptoms of PD (75.6%). CONCLUSION: Among ropinirole, rasagiline, rotigotine, entacapone, apomorphine, pramipexole, sumanirole, bromocriptine, piribedil and levodopa, with placebo as a control, apomorphine may be the most efficacious drug for therapy in treating the non-motor symptoms of PD.


Subject(s)
Dopamine Agonists/therapeutic use , Parkinson Disease/drug therapy , Apomorphine/therapeutic use , Bayes Theorem , Databases, Factual , Humans , Parkinson Disease/pathology , Severity of Illness Index , Treatment Outcome
4.
Sci Adv ; 3(3): e1601284, 2017 Mar.
Article in English | MEDLINE | ID: mdl-28275729

ABSTRACT

The conservation of World Heritage is critical to the cultural and social sustainability of regions and nations. Risk monitoring and preventive diagnosis of threats to heritage sites in any given ecosystem are a complex and challenging task. Taking advantage of the performance of Earth Observation technologies, we measured the impacts of hitherto imperceptible and poorly understood factors of groundwater and temperature variations on the monuments in the Angkor World Heritage site (400 km2). We developed a two-scale synthetic aperture radar interferometry (InSAR) approach. We describe spatial-temporal displacements (at millimeter-level accuracy), as measured by high-resolution TerraSAR/TanDEM-X satellite images, to provide a new solution to resolve the current controversy surrounding the potential structural collapse of monuments in Angkor. Multidisciplinary analysis in conjunction with a deterioration kinetics model offers new insights into the causes that trigger the potential decline of Angkor monuments. Our results show that pumping groundwater for residential and touristic establishments did not threaten the sustainability of monuments during 2011 to 2013; however, seasonal variations of the groundwater table and the thermodynamics of stone materials are factors that could trigger and/or aggravate the deterioration of monuments. These factors amplify known impacts of chemical weathering and biological alteration of temple materials. The InSAR solution reported in this study could have implications for monitoring and sustainable conservation of monuments in World Heritage sites elsewhere.

5.
Zhongguo Zhen Jiu ; 36(10): 1027-1030, 2016 Oct 12.
Article in Chinese | MEDLINE | ID: mdl-29231520

ABSTRACT

OBJECTIVE: To explore the efficacy of local acupuncture therapy on post-stroke pseudo-bulbar palsy and the clinical advantageous protocol of local acupuncture therapy. METHODS: Eighty patients of post-stroke pseudo-bulbar palsy were randomized into a quick needle insertion group and a routine acupuncture group, 40 cases in each one. The western medicine, such as thrombolysis, lipid regulation, antiplatelet aggregation, antihypertension and hypoglycemic therapy method was all used in the two groups. On the basis of the treatment of western medicine, in the quick needle insertion group, the perpendicular needle insertion was used at Aqiang point, about 8 to 12 mm in depth. When the emptiness feeling presented under the needle, the needle went slowly for 2 mm more depth till cough occurred, and removed afterward. The treatment was given once every day, and totally 20 treatments were required. In the routine acupuncture group, Lianquan (CV 23) was stimulated. The needle was inserted toward the tongue root, about 40 mm in depth. The needle was rotated till the patient felt soreness and distention at the tongue root, and then retained for 30 min. The treatment was given once a day, and totally 20 treatments were required. The water swallow test score and clinical efficacy were evaluated before and after treatment. RESULTS: The curative rate was 80.0% (32/40) in the quick needle insertion group, better than 55.0% (22/40) in the routine acupuncture group (P<0.05). The total effective rate was 97.5% (39/40) in the quick needle insertion group and was 90.0% (36/40) in the routine acupuncture group, indicating no significant difference in comparison (P>0.05). The water swallow test scores decreased after treatment as compared with those before treatment in the two groups (both P<0.01), and the water swallow test scores after treatment of the two groups had no significant difference (P>0.05). CONCLUSIONS: Acupuncture at local point is effective for post-stroke pseudo-bulbar palsy.The curative rate of quick needle insertion at Aqiang point is better than routine acupuncture at Lianquan (CV 23).


Subject(s)
Acupuncture Points , Bulbar Palsy, Progressive/therapy , Stroke/complications , Acupuncture Therapy/methods , Bulbar Palsy, Progressive/etiology , Deglutition Disorders/therapy , Humans , Thrombolytic Therapy/methods , Treatment Outcome
SELECTION OF CITATIONS
SEARCH DETAIL