ABSTRACT
Behçet's disease (BD) is a rare autoimmune disease with an unknown aetiology. It is mostly found in the ancient "silk route" (from the Mediterranean region to the Far East). BD is a vasculitis that can involve veins and arteries of all sizes. Clinical features are dominated by oral and genital aphthous ulcers and uveitis. Central nervous system manifestations include parenchymal (80%) and non-parenchymal involvement (20%). Non-parenchymal forms can include cerebral venous thrombosis. Treatment is based on anti-inflammatory, immunosuppressive and anticoagulant agents, but it remains controversial. We report a rare case of a unilateral jugular being thrombosis revealing BD in a young Moroccan male. He was admitted due to neuro-ophthalmological manifestations (diplopia, and bilateral papilloedema). A good outcome occurred after treatment with anti-inflammatory drugs and anti-coagulation.
Subject(s)
Eye Infections , Iris Diseases , Child , Diagnosis, Differential , Humans , Iris Diseases/diagnostic imagingABSTRACT
PURPOSE: To determine whether phacoemulsification with intraocular lens implantation has a greater impact on the corneal endothelium of type 2 diabetic patients compared to non-diabetic patients. MATERIALS AND METHODS: This study compared the endothelial status in 32 diabetics with good glycemic control and 32 non-diabetic patients before and after uneventful phacoemulsification. Central corneal thickness (CCT), central corneal endothelial cell density (CD), hexagonal cell percentage (HEX), and percent coefficient of variation (% CV) were measured using a specular microscope. RESULTS: Data were matched by age and sex. Diabetics showed a significantly higher loss of endothelial cells compared to non-diabetics. After 3 months, there was a decline of 165 endothelial cells (SD 97) in the diabetic group and 114 (SD 45) in the control group. This was statistically significant (P=0.0065). In addition, diabetics showed a slower recovery trend of endothelial healing as evidenced by a lower CV variation. The CV change was 4.7 in the control group and 3.2 in the diabetic group, which was statistically significant (P=0.023). A significant correlation was found between the energy used and the change in endothelial count as well as the CV in both groups. CONCLUSION: Despite good glycemic control, diabetics have significantly more endothelial damage compared to non-diabetics with a similar nuclear classification and phacoemulsification energy used. This justifies a more careful use of phacoemulsification energy in diabetics.