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Analysis of borderline oxacillin-resistant Staphylococcus aureus (BORSA) strains isolated in Tunisia.
Maalej, Senda Mezghani; Rhimi, Faouzia Mahjoubi; Fines, Marguerite; Mnif, Basma; Leclercq, Roland; Hammami, Adnene.
J Clin Microbiol ; 50(10): 3345-8, 2012 Oct.
Article in English | MEDLINE | ID: mdl-22814459

ABSTRACT

Twenty-three strains of Staphylococcus aureus with borderline resistance to oxacillin were studied. These strains were not detected by the cefoxitin test, tests for penicillin-binding protein 2a (PBP2a), mecA, and mecA(LGA251) were negative, and the strains were genetically unrelated. To detect all strains resistant to oxacillin, laboratories should routinely test for both cefoxitin and oxacillin.


Subject(s)
Anti-Bacterial Agents/pharmacology , Drug Resistance, Bacterial , Methicillin-Resistant Staphylococcus aureus/drug effects , Oxacillin/pharmacology , Staphylococcal Infections/microbiology , Bacterial Proteins/genetics , Cefoxitin/pharmacology , Cluster Analysis , Electrophoresis, Gel, Pulsed-Field , Humans , Methicillin-Resistant Staphylococcus aureus/isolation & purification , Microbial Sensitivity Tests/methods , Molecular Epidemiology , Molecular Typing , Penicillin-Binding Proteins/genetics , Staphylococcal Infections/epidemiology , Tunisia/epidemiology
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