ABSTRACT
INTRODUCTION: Adequate bowel cleansing which is acceptable to the patient is a prerequisite for safe and effective colonoscopy. A 2-L polyethylene glycol solution containing ascorbic acid and electrolytes (PEG-Asc) is an alternative to sodium picosulphate + magnesium citrate (SPS-Mg) for bowel preparation. The aim of the current study is to compare PEG-Asc to SPS-Mg in terms of tolerability and efficacy. METHODS: This was a single blind, randomized controlled trial. A blinded assessment of bowel cleansing was made by the attending endoscopist. Patients completed a questionnaire on the acceptability of the preparation. RESULTS: One hundred and thirty (130) consecutive patients attending for day case colonoscopy were randomly allocated to bowel preparation with PEG-Asc (n = 66) or SPS-Mg (n = 64). More patients found PEG-Asc to taste unpleasant (37.9 vs. 10.9%, P < 0.001) and more patients found PEG-Asc to be a more distressing preparation than SPS-Mg (15.1 vs. 4.7%, P = 0.043). However, there was no difference in the proportion of patients being able to complete bowel preparation (PEG-Asc vs. SPS-Mg, 92.4 vs. 93.8%, P = 0.520). There was no detectable difference between PEG-Asc and SPS-Mg in the quality of cleansing with a good or very good preparation being reported by the endoscopist in 46.9 and 54.5% of cases, respectively (P = 0.242). CONCLUSIONS: More patients find PEG-Asc to taste unpleasant and to be a more distressing preparation than SPS-Mg. However, there was no detectable difference between PEG-Asc and SPS-Mg in bowel cleansing prior to colonoscopy.
Subject(s)
Cathartics/administration & dosage , Citrates/administration & dosage , Citric Acid/administration & dosage , Colonoscopy/methods , Organometallic Compounds/administration & dosage , Picolines/administration & dosage , Polyethylene Glycols/administration & dosage , Adult , Aged , Ascorbic Acid/administration & dosage , Female , Humans , Male , Middle Aged , Single-Blind Method , Surveys and QuestionnairesABSTRACT
In 1995, Morinaga reported on a new technique in the treatment of haemorrhoids. It relies on the reduction of haemorrhoidal vascular flow by suturing haemorrhoidal arteries. The artery is located by Doppler ultrasound transducer, haemorrhoidal artery ligation (HAL). This pilot study shows initial experience with HAL in patients with internal haemorrhoidal disease. A prospective study was performed in 35 patients treated by (HAL). After a mean of 18 (range 12-24) months patients were administered a standardized questionnaire by telephone. The treatment's success was observed in 11 of 12 patients (91.5%) with pain, 28 of 33 (85%) with bleeding, 14 of 15 (93%) with Pruritus, 12 of 13 (92%) with discharge, and 17 of 21 (81%) with prolapse. Open haemorrhoidectomy was mandatory in 3 patients (8.5%) due to bleeding and prolapse. HAL is simple, painless, safe, and effective method.