ABSTRACT
Treatment decision making in cancer patients is dependent on tumour variables, patient variables, and physician bias. Patient age and socio-economic status were examined as independent variables in treatment decision making. Bias towards offering treatment options to younger, more socially active patients was found.
Subject(s)
Aging , Decision Making , Neoplasms/therapy , Social Class , HumansSubject(s)
Urethra/injuries , Erectile Dysfunction/etiology , Fractures, Bone/complications , Humans , Male , Pelvic Bones/injuries , Postoperative Complications , Radiography , Retrospective Studies , Rupture , Urethra/diagnostic imaging , Urethra/surgery , Urethral Stricture/etiology , Urinary Bladder/surgerySubject(s)
Antigen-Antibody Complex , Cystitis/etiology , Lupus Erythematosus, Systemic/immunology , Antibodies, Antinuclear/analysis , Chronic Disease , Cystitis/immunology , Cystitis/pathology , Humans , Lupus Erythematosus, Systemic/complications , Lupus Erythematosus, Systemic/pathology , Urinary Bladder/pathologyABSTRACT
The Brompton mixture is a highly effective, flexible, safe and convenient means to control chronic pain of malignant disease. The mixture is a solution containing morphine, the dose of narcotic varying with the need for analgesia, and is given regularly, usually every 4 hours, with a phenothiazine. The main aims of therapy are prevention of pain rather than treatment, an unclouded sensorium and a normal effect. Terminally ill cancer patients were given the Brompton mixture and a phenothiazine in an attempt to control their pain. The mixture was administered to patients in 3 hospital environments: 1) a palliative care unit, 2) general wards and 3) private rooms. Pain was measured in 92 patients with the McGill-Melzack pain questionnaire. The Brompton mixture controlled pain in 90 per cent of patients in the palliative care unit and in 75 to 80 per cent of patients in the wards or private rooms. The differences in pain scores between patients in the palliative care unit and the other groups were significant. The mixture produced substantial decreases in the 3 major dimensions of pain: 1) sensory, 2) affective and 3) evaluative. Comparison of these results with data obtained in an outpatient pain clinic showed that the Brompton mixture was strikingly more effective than the traditional methods of managing cancer pain.
Subject(s)
Analgesics, Opioid/therapeutic use , Neoplasms/complications , Pain, Intractable/drug therapy , Palliative Care , Analgesics, Opioid/administration & dosage , Analgesics, Opioid/adverse effects , Female , Humans , Male , Middle Aged , Morphine/administration & dosage , Pain, Intractable/etiology , Pain, Intractable/physiopathologySubject(s)
Ureter/abnormalities , Humans , Terminology as Topic , Ureter/pathology , Ureter/physiopathologyABSTRACT
The Brompton mixture is a highly effective, flexible, safe and convenient means to control chronic pain of malignant disease. The mixture is a solution containing morphine, the dose of narcotic varying with the need for analgesia, and is given regularly, usually every 4 hours, with a phenothiazine. The main aims of therapy are prevention of pain rather than treatment, an unclouded sensorium and a normal effect. Terminally ill cancer patients were given the Brompton mixture and a phenothiazine in an attempt to control their pain. The mixture was administered to patients in 3 hospital environments: 1) a palliative care unit, 2) general wards and 3) private rooms. Pain was measured in 92 patients with the McGill-Melzack pain questionnaire. The Brompton mixture controlled pain in 90 per cent of patients in the palliative care unit and in 75 to 80 per cent of patients in the wards or private rooms. The differences in pain scores between patients in the palliative care unit and the other groups were significant. The mixture produced substantial decreases in the 3 major dimensions of pain: 1) sensory, 2) affective and 3) evaluative. Comparison of these results with data obtained in an outpatient pain clinic showed that the Brompton mixture was strikingly more effective than the traditional methods of managing cancer pain.
Subject(s)
Morphine/therapeutic use , Pain, Intractable/prevention & control , Palliative Care/methods , Aged , Drug Administration Schedule , Female , Hospital Units , Humans , Male , Middle Aged , Morphine Derivatives/therapeutic use , Neoplasms/drug therapy , Pain, Intractable/drug therapy , Phenothiazines/therapeutic use , Surveys and Questionnaires , Terminal Care/standardsABSTRACT
12 patients who had previously undergone trans-sphincteric urethral reconstruction were studied with regard to their sphincter mechanisms. The method of study was by urethral pressure profile and urethral voluntary sphincteric pressure increment. This study showed that patients may undergo trans-sphincteric urethral reconstruction with preservation of normal profiles and voluntary pressure increases indicating preservation of the "external" sphincter mechanism.
