Effects of Mixed Isoenergetic Meals on Fat and Carbohydrate Metabolism during Exercise in Older Men.

The present study was designed to investigate the effects of four different meals on fat and CHO metabolism during subsequent exercise in elderly males. Eight healthy males (age: 63.3 ± 5.2 years) reported to the physiology laboratory on four separate occasions, each of which was allocated for the performance of a 30-minute exercise on a cycle ergometer at 60% [Formula: see text] after having normal (N), high fat (HF), high carbohydrate high glycaemic index (HGI) and high carbohydrate low glycaemic index (LGI) meals. Fat oxidation during exercise after the meals (HF = 0.26 ± 0.04 g/min; N = 0.21 ± 0.04 g/min; HGI = 0.22 ± 0.03 g/min; LGI = 0.19 ± 0.03 g/min) was not significant (P > .05), and neither were the rates of carbohydrate oxidation (N = 1.79 ± 0.28, HF = 1.58 ± 0.22, HGI = 1.68 ± 0.22, and LGI = 1.77 ± 0.21 g/m). NEFA concentration increased after HF (P < .05) but decreased after HGI and LGI (P < .05). Glucose concentration decreased as a result of exercise after HF, and LGI (P < .05) whereas insulin concentration decreased significantly during exercise after N, HF, and HGI (P < .05). It can be concluded that, in elderly males, feeding isoenergetic meals containing different proportions of carbohydrate and fat do not significantly alter oxidation of fat and CHO during exercise in spite of changes in some circulating metabolites.

Effects of exercise intensity and duration on fat metabolism in trained and untrained older males.

Advancing age is associated with changes in fat and carbohydrate (CHO) metabolism, which is considered a risk factor for cardiovascular disease and diabetes. The effects of exercise intensity and duration on fat and CHO metabolism in elderly male subjects were investigated in the present study. Seven trained (63.7+/-4.7 years) and six untrained (63.5+/-4.5 years) healthy males performed three 30 min trials on a cycle ergometer at 50, 60 and 70% VO2max and two other trials at 60 and 70% VO2max in which the total energy expenditure was equal to that for 30 min at 50% VO2max Respiratory measures were undertaken throughout the exercise and blood samples taken before and immediately after each trial. Statistical analyses revealed a significant effect of exercise intensity on fat oxidation when the exercise durations were equated as well as when the energy expenditure was held constant for the three trials, though no training effect was noted. Total carbohydrate oxidation increased significantly with exercise intensity (P<0.05) and with training. Significantly higher levels of non-esterified free fatty acid (NEFA) and glycerol were observed for trained compared with untrained though not for B-hydroxybutyrate (3-OH) or insulin. No differences in NEFA, glycerol, 3-OH were evident for increases in exercise intensity. Carbohydrate and fat oxidation are significantly affected by exercise intensity in elderly males, although only CHO oxidation is influenced by training. Furthermore, training-induced increases in the availability of NEFA and glycerol are not associated with an increase in fat oxidation, rather an increase in CHO oxidation.

Responses of platelet activation and function to a single bout of resistance exercise and recovery.

The present study was designed to investigate the effects of resistance exercise and recovery on platelet activation and function. Twenty one healthy male subjects (27.9 +/- 4.8 years) completed three sets of five to seven repetitions of six exercises at an intensity corresponding to 80% of one repetition maximum (1RM), which was followed by 30 minutes recovery. Venous blood samples (20 ml) were obtained before, immediately after exercise and at the end of recovery and were analysed for platelet indices, platelet aggregation using collagen and various final concentrations of adenosine-5'-diphosphate (ADP), and beta thromboglobulin (B-TG). Resistance exercise was followed by a significant increase in corrected platelet count, corrected plateletcrit, and B-TG. These increases were transient and decreased to pre-exercise level at the end of recovery. When plasma samples were not corrected for changes in platelet count, exercise was followed by a significant increase (P < 0.05) in platelet aggregation using high concentration of ADP. With corrected samples, platelet aggregation and B-TG were not altered after exercise and recovery. It was concluded that heavy resistance exercise induces in vivo activation of platelets as manifested by an increase in platelet aggregation and a rise in B-TG and that these changes could be explained partially by changes in plasma volume and platelet count induced by exercise.

Effects of water intake on the responses of haemorheological variables to resistance exercise.

To examine the effects of drinking an amount of water equal to weight loss on the responses of blood rheological variables, eleven healthy male subjects performed three resistance exercise trials. The aim of the first session was to determine the amount of weight loss following a resistance exercise trial at 80% of one repletion maximum (1RM). In the second and third sessions subjects performed the same resistance exercise protocol without and with drinking an amount of water equal to that recorded for body weight loss. Three venous blood samples were taken before exercise, immediately after exercise, and at the end of 30-min recovery and were analysed for haematocrit (Hct), haemoglobin (Hb), blood cells count and the main determinant of blood rheology. Haematocrit, plasma viscosity, fibrinogen, albumin, and total protein were significantly increased in response to resistance exercise and returned to pre-exercise level following 30-min of recovery. The changes in blood rheological variables in response to resistance exercise occurred similarly in both control and water trials with no significant difference being observed between trials. Plasma volume loss through sweating and respiratory tract during resistance exercise could have contributed to the decrease in plasma volume, though, this contribution was negligible. Therefore, it is concluded that the increases in blood rheological variables in response to resistance exercise are mainly due to plasma shifts from intravascular space to extravascular spaces rather than plasma volume loss through sweating and respiratory tract.

Physiological and metabolic aspects of very prolonged exercise with particular reference to hill walking.

Hill walking is a popular recreational activity in the developed world, yet it has the potential to impose severe stress simultaneously upon several regulatory systems. Information regarding the physiological strain imposed by prolonged walking outdoors in adverse climatic conditions was reported almost four decades ago and recent research has extended some of this work. These data indicate that once the walker fatigues and starts to slow or stops walking altogether, the rate of heat production falls dramatically. This decrease alone predisposes to the development of hypothermia. These processes, in adverse weather conditions and/or during periods when the level of exertion is low (with low heat production), will be accelerated. Since the majority of walkers pursue this activity in groups, the less fit walkers may be more susceptible to fatigue when exercising at a higher relative intensity compared with their fitter counterparts. The best physiological offset for hypothermia is to maintain heat production by means of exercise, and so fatigue becomes a critical predisposing factor; it is as important to facilitate heat loss, especially during periods of high exertion, as it is to maintain heat production and preserve insulation. This can be partly achieved by clothing adjustments and consideration of the intensity of exercise. Failure to provide adequate energy intake during hill walking activities has been associated with decreased performance (particularly with respect to balance) and impaired thermoregulation. Such impairments may increase susceptibly to both fatigue and injury whilst pursuing this form of activity outdoors. The prolonged low to moderate intensity of activity experienced during a typical hill walk elicits marked changes in the metabolic and hormonal milieu. Available data suggest that during hill walking, even during periods of acute negative energy balance, blood glucose concentrations are maintained. The maintenance of blood glucose concentrations seems to reflect the presence of an alternative fuel source, a hormonally induced increase in fat mobilisation. Such enhancement of fat mobilisation should make it easier to maintain blood glucose by decreasing carbohydrate oxidation and promoting gluconeogenesis, thus sparing glucose utilisation by active muscle. During strenuous hill walking, older age walkers may be particularly prone to dehydration and decreased physical and mental performance, when compared with their younger counterparts. In summary, high rates of energy expenditure and hypohydration are likely to be closely linked to the activity. Periods of adverse weather, low energy intake, lowered fitness or increased age, can all increase the participants' susceptibility to injury, fatigue and hypothermia in the mountainous environment.

The effects of changing pace on metabolism and stroke characteristics during high-speed breaststroke swimming.

Performances often vary between the heats and finals of breaststroke swimming competitions possibly because the swimmers try to conserve their energy, or for other tactical reasons. Additionally, coaches might advise either a 'positive' or 'even' pace race strategy during the final. The effect of such pacing changes on metabolism (blood lactate, heart rate, ventilation), ratings of perceived exertion, stroke kinematics and turning times have not been investigated. Nine male competitive breaststroke swimmers swam three paced (Aquapacer) 200-m trials, 48 h apart and in random order, at 98%, 100% and at an attempted 102% of their maximal 200-m time-trial speed. Responses in metabolic variables were similar between the 98% and 100% trials, but higher post-exercise blood lactate concentrations and respiratory exchange ratios were observed following the 102% trial. As the pace of trials increased, stroke rate was found to increase proportionately with stroke count. However, during the latter stages of the 100% trial, a disproportionate increase in the stroke count was observed, which led to a significant pacing error. This feature was more obvious in the 102% trial, where participants demonstrated 'positive pacing' and reported higher ratings of perceived exertion than for the 98% trial. During the early stages of the trials, turning times were initially shorter the faster the pace of the trial; however, as the trials progressed, this pattern was found to reverse. We conclude that a slight reduction in pace during near maximal breaststroke swimming altered kinematic but not post-exercise metabolic responses, while an increase in pace led to positive pacing and an increase in both kinematic responses and anaerobic metabolism.

Physiological, metabolic, and performance implications of a prolonged hill walk: influence of energy intake.

We aimed to examine the effects of different energy intakes on a range of responses that are relevant to the safety of hill walkers. In a balanced design, 16 men completed a strenuous self-paced mountainous hill walk over 21 km, under either a low-energy (2.6 MJ; 616 kcal) intake (LEI) or high-energy (12.7 MJ; 3,019 kcal) intake (HEI) condition. During the hill walk, rectal temperatures were measured continuously, and blood samples for the analysis of metabolites and hormones were drawn before breakfast and immediately after the walk. Subjects also completed a battery of performance tests that included muscular strength, reaction times, flexibility, balance, and kinesthetic differentiation tests. During the LEI, mean blood glucose concentrations leveled off at the low-middle range of normoglycemia, whereas, on the HEI, they were significantly elevated compared with the LEI. The maintained blood glucose concentrations, during the LEI, were probably mediated via the marked fat mobilization, reflected by a two- to fivefold increase in nonesterified fatty acids, 3-hydroxybutyrate, and glycerol concentrations. The LEI group showed significantly slower one- and two-finger reaction time, had an impaired ability to balance, and were compromised in their ability to maintain body temperature, when compared with the HEI group. The modestly impaired performance (particularly with respect to balance) and thermoregulation during the LEI condition may increase susceptibility to both fatigue and injury during the pursuit of recreational activity outdoors.

Accuracy of pacing during breaststroke swimming using a novel pacing device, the Aquapacer.

Generally, swimmers pace themselves using their own judgement and the poolside clock during swimming training, fitness testing protocols or scientific investigation. The Aquapacer is a new pacing device that can be used to pace the swimming speed or stroke rate of the swimmer. The aims of this study were to determine if breaststroke swimmers could pace accurately during submaximal swimming using a poolside clock (Study 1) and the Aquapacer (Study 2), at swimming speeds at, just above and just below maximal 200 m time-trial speeds (using the Aquapacer, Study 3) and under three different race pacing conditions (using the Aquapacer, Study 4). Between 8 and 15 male national or club standard 200 m breaststroke swimmers participated in each of the studies. The swimmers in Study 2, despite being less well trained than the swimmers in Study 1 and part of a more heterogeneous group in terms of swimming performance, repeatedly demonstrated less random error in pacing, suggesting that the Aquapacer may be preferable to the poolside clock when swimmers are being required to pace accurately. The Aquapacer also enabled swimmers to pace accurately at race-specific swimming speeds (until fatigue precluded them from holding pace) (Study 3), and through a change in pace at race-specific speeds (Study 4), which suggests that it may be of use in entraining racing strategies.