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1.
J Surg Oncol ; 119(7): 979-986, 2019 Jun.
Article in English | MEDLINE | ID: mdl-30729542

ABSTRACT

BACKGROUND AND OBJECTIVES: This study is a systematic review with meta-analysis designed to compare the perioperative and oncological outcomes of the abdominoperineal resection (APR) carried out in the prone jack-knife position (P-APR) vs the classic lithotomy position (C-APR). METHODS: We conducted an electronic search through PubMed utilizing the PRISMA guidelines. We included all randomized and nonrandomized studies which allowed for comparative analysis between the two groups. Research that focused on and analyzed the extralevator abdominal excision were excluded. Pooled variables and number of events were analyzed using the random-effect model. RESULTS: The final analysis included seven nonrandomized retrospective cohorts encompassing 1663 patients. P-APR was associated with decreased operative time (OT) (DM, -43.8 minutes; P < 0.01) and estimated blood loss (EBL) (DM, 86.9 mL; P < 0.01). There were no observed differences regarding perineal wound infections (PWI) (odds ratio [OR], 0.36; P = 0.18), intraoperative perforation of rectum (IOP) (OR, 0.98; P = 0.97), circumferential resection margin (CRM) positivity (OR, 1.02; P = 0.98) or 5-year LR (OR, 1.00; P = 0.99). CONCLUSION: The prone approach for APR is associated with decreased EBL and OT, although not with any change in the incidence of PWI or IOP. Moreover, surgical positioning per se does not appear to affect the CRM positivity rates or LR rate.


Subject(s)
Patient Positioning/methods , Proctectomy/methods , Rectal Neoplasms/surgery , Humans , Margins of Excision , Prone Position , Randomized Controlled Trials as Topic , Retrospective Studies , Treatment Outcome
2.
J Robot Surg ; 12(2): 303-310, 2018 Jun.
Article in English | MEDLINE | ID: mdl-28730536

ABSTRACT

Gastric neurostimulation (GNS) with Enterra® therapy device (Medtronic, Minneapolis, MN) appears as the last resort for patients with refractory gastroparesis. Currently, the device has Humanitarian Use status by Food and Drug Administration, thereby requiring further investigation. We aim to describe its feasibility and clinical outcomes using robotic technique. From June 2014 to September 2016, 15 consecutive patients underwent robotic insertion of Enterra® device. Patient demographics, comorbidities, and clinical outcomes including mortality, length of stay, readmission rates, reoperation and complications were retrospectively collected. Patients were also assessed based on a validated 14-point questionnaire regarding satisfaction with the operation, quality of life and symptomatic relief. Mean age was 41.6 years ± 13.8 and there were 11 females (73.3%). No mortality was reported. The annual hospital admissions were reduced after GNS (2.5 ± 4.1 vs. 3.6 ± 4.4, p = 0.004). The frequency of bloating (p = 0.029) and severity of emesis (p = 0.038), early satiety (p = 0.042) and bloating (p = 0.031) were reduced after GNS. The severity and frequency total scores were also improved after GNS (12.6 ± 1.4 vs. 18.1 ± 2.7, p = 0.008 and 12.9 ± 2.2 vs. 16.1 ± 1.1, p = 0.016, respectively). This is the first report describing the clinical experience with robotic insertion of GNS device. This approach is safe and feasible and seems to have similar long-term outcomes as laparoscopic technique. Potential advantages to robotic technique include enhanced dexterity and suturing of the device within gastric wall. Further experience with large prospective studies and randomized clinical trials may be warranted.


Subject(s)
Gastroparesis/surgery , Implantable Neurostimulators , Robotic Surgical Procedures/adverse effects , Robotic Surgical Procedures/instrumentation , Adult , Feasibility Studies , Female , Humans , Male , Middle Aged , Nausea , Postoperative Complications , Retrospective Studies , Treatment Outcome , Vomiting
3.
Obes Surg ; 27(10): 2768-2772, 2017 10.
Article in English | MEDLINE | ID: mdl-28808884

ABSTRACT

BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) may exacerbate gastroesophageal reflux disease (GERD) in patients with a hiatal hernia (HH). Surgical repair may be needed, however prior LSG precludes standard HH repair with fundoplication. METHODS: We retrospectively reviewed our experience with bariatric patients with prior LSG undergoing laparoscopic HH repair from August 2010 to July 2016. Patient demographics and outcomes including mortality, length of stay (LOS), readmission rates, reoperation, and complications were described. A validated 13-point questionnaire was used to determine symptomatic relief, weight loss, and overall satisfaction. RESULTS: A total of nine consecutive patients with prior LSG underwent HH repair and were included in the analysis. Repair was performed using Bio-A Gore® mesh (W.L Gore Inc., Newark, DE) in six (66.7%) cases and posterior cruroplasty in three (33.3%) patients. Heartburn was significantly decreased at 1 year (1.4 ± 0.9 vs. 2.6 ± 0.9, p = 0.031), and 78% of patients reported some degree of symptomatic relief after HH repair. CONCLUSIONS: Laparoscopic HH repair offers a safe and feasible approach in the management of persistent GERD after LSG in well-selected bariatric patients. Larger prospective studies are warranted to investigate the effectiveness of HH repair in this population as 22% of our patients did not demonstrate postoperative symptomatic improvement.


Subject(s)
Gastrectomy , Hernia, Hiatal/complications , Hernia, Hiatal/surgery , Herniorrhaphy , Obesity, Morbid/complications , Obesity, Morbid/surgery , Adult , Female , Fundoplication/adverse effects , Fundoplication/methods , Gastrectomy/adverse effects , Gastrectomy/methods , Gastroesophageal Reflux/prevention & control , Herniorrhaphy/adverse effects , Humans , Laparoscopy/adverse effects , Length of Stay , Male , Middle Aged , Postoperative Complications/etiology , Retrospective Studies , Treatment Outcome , Weight Loss
4.
J Gastrointest Surg ; 21(10): 1723-1731, 2017 Oct.
Article in English | MEDLINE | ID: mdl-28744743

ABSTRACT

BACKGROUND: Despite significant improvement in operative mortality rates following pancreaticoduodenectomy (PD), morbidity remains high. Outcomes following PD may be improved in high-volume centers and with high-volume surgeons. We sought to evaluate the association between surgeon experience and postoperative outcomes after PD. METHODS: An online database search of MEDLINE and EMBASE was performed; key bibliographies were reviewed. Studies comparing operative outcomes of high-volume surgeon (HVS) and low-volume surgeon (LVS) performing PD were included. Odds ratios with the corresponding 95% confidence intervals (CI) by random fixed effects models of pooled data were calculated. Definition of HVS varied among the studies, ranging from 6 to >20 PD/year. The primary endpoint was 30-day mortality, and secondary outcomes were complication rates, length of stay (LOS), hospital costs, and readmission rates. Study quality was assessed using STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) criteria. RESULTS: Search strategy yielded 360 publications. Eleven studies met the inclusion criteria comprising 36,449 patients. Among these patients, 12,512 (34.3%) PDs were performed by HVS and 23,937 (65.7%) by LVS. Meta-analysis of included studies showed that HVS had significantly lower mortality rates than LVS (2.4 vs. 6.7%, OR 2.88; 95% CI 2.51-3.27, p < 0.001). They also had significantly lower overall complication rates (36.3 vs. 50.3%, OR 1.71; 95% CI 1.62-1.81, p < 0.001), hospital costs (range $10,818-141,322 vs. $12,114-198,678, OR 0.13; 95% CI 0.07-0.19, p < 0.001), and LOS (range 11-35 vs. 14-38 days, OR 2.86; 95% CI 2.03-3.68, p < 0.001). CONCLUSIONS: HVS performing PD have significantly better outcomes than LVS in terms of decreased mortality, morbidity, LOS, and hospital costs. Efforts toward increased regionalization of care should be discussed. Consensus regarding definition of HVS needs to be undertaken.


Subject(s)
Clinical Competence , Pancreaticoduodenectomy/mortality , Surgeons/statistics & numerical data , Humans , Length of Stay/statistics & numerical data , Models, Statistical , Odds Ratio , Outcome Assessment, Health Care , Patient Readmission/statistics & numerical data , Postoperative Complications/epidemiology , Postoperative Complications/etiology
5.
J Hepatobiliary Pancreat Sci ; 24(5): 268-280, 2017 May.
Article in English | MEDLINE | ID: mdl-28251830

ABSTRACT

BACKGROUND: Pancreatoduodenectomy (PD) carries a high morbidity. Over time, pancreatic surgeons have altered their perioperative management in efforts to reduce morbidity rates, thereby creating major technical and management variations. We aim to evaluate the practice patterns of hepato-pancreato-biliary (HPB) surgeons across multiple regions worldwide. METHODS: Between May and August 2015, an anonymous 25-item survey questionnaire was electronically distributed to the International Hepato-Pancreato-Biliary Association members regarding practice patterns and perioperative care of patients undergoing PD. Responses were analyzed based on three variables: geographical region, institution type and volume status. RESULTS: Among 285 participants, the majority were high-volume surgeons (80.4%) at academic institutions (56.1%) from the United States (34.7%), Europe (28.1%) and Asia (14.3%). North American surgeons are more likely to limit prophylactic antibiotic within 24 h postoperatively (P < 0.001), whereas European surgeons more often culture bile intraoperatively (P = 0.024). There are significant variations between different institution types and HPB surgeons based on case volume. Very-high volume surgeons (>50 cases/year) are more likely to routinely culture intraoperative bile (64% vs. 33.3-37.5%) and close incision with subcuticular sutures (42.5% vs. 15.3-25.9%). CONCLUSIONS: Our survey demonstrated significant heterogeneity in perioperative management between HPB surgeons across different regions worldwide. Further studies are warranted to assess the impact of these variations on outcomes of patients undergoing PD. Efforts should be directed towards standardization of perioperative management of PD.


Subject(s)
Disease Management , Pancreatic Diseases/surgery , Pancreatic Fistula/prevention & control , Pancreaticoduodenectomy/adverse effects , Secondary Prevention/methods , Surgical Wound Infection/prevention & control , Cross-Sectional Studies , Female , Global Health , Humans , Incidence , Male , Pancreatic Fistula/epidemiology , Pancreatic Fistula/etiology , Pilot Projects , Surgical Wound Infection/epidemiology , Surgical Wound Infection/etiology , Surveys and Questionnaires , Survival Rate/trends
6.
HPB (Oxford) ; 19(2): 99-103, 2017 02.
Article in English | MEDLINE | ID: mdl-27993464

ABSTRACT

BACKGROUND: Although acute cholecystitis (AC) is a surgical disease, patients with the condition may be admitted to medical-related services (MS). This may lead to delayed cholecystectomy thereby affecting outcomes and quality of care. METHODS: Between July 2010 and March 2013, 329 patients under 70 years old presented to a community-based tertiary care hospital with AC and underwent same admission cholecystectomy. Outcomes were compared between patients admitted to MS and surgical services (SS). RESULTS: Two hundred fifteen patients (65.3%) were admitted to a MS. Patients under the MS had longer LOS (3.0 days vs. 2.0 days, p < 0.001), waiting time to surgical consultation (7.3 h vs. 5.0 h, p < 0.001) and to cholecystectomy (1.0, 0-2 days vs. 1.0, 0-1 day, p < 0.001), and increased hospital costs ($3685 vs. $4,688, p < 0.001) compared to the SS. Readmission and mortality rates were not significantly different between groups. CONCLUSION: Patients under 70 years old with AC undergoing cholecystectomy admitted to MS had increased LOS, delay to the operation, and hospital costs compared to those admitted to a SS. Admission of patients with AC to a SS needs to be emphasized to reduce costs and improve quality of care.


Subject(s)
Cholecystectomy , Cholecystitis, Acute/surgery , Patient Admission , Adult , Aged , Cholecystectomy/adverse effects , Cholecystectomy/economics , Cholecystectomy/mortality , Cholecystitis, Acute/diagnosis , Cholecystitis, Acute/economics , Cholecystitis, Acute/mortality , Cost Savings , Cost-Benefit Analysis , Female , Hospital Costs , Humans , Length of Stay , Male , Middle Aged , Missouri , Patient Admission/economics , Patient Readmission , Referral and Consultation , Retrospective Studies , Tertiary Care Centers , Time Factors , Time-to-Treatment , Treatment Outcome
7.
Am J Surg ; 213(3): 498-501, 2017 Mar.
Article in English | MEDLINE | ID: mdl-27890330

ABSTRACT

PURPOSE: During general surgery (GS) training, residents are expected to accurately interpret radiologic images. Objective evidence evaluating residents' ability to provide accurate interpretation of imaging studies is currently lacking. METHODS: A 30-item web-based test was developed using images from different radiologic modalities. Residents from 6 ACGME accredited GS programs participated. Residents from 1 radiology program served as a control group. RESULTS: 74 GS residents (GSR) enrolled in the online test. The mean score for GSR was 75% (±9) and 83% (±6) for RR (p = 0.006). Residents correctly answered 63% x-rays, 74%, CT(head), 84% CT(body), 69% ultrasound, and 88% tube/line localization questions. Senior residents were more proficient than junior residents at interpreting CT (body) and ultrasound images. CONCLUSION: GS residents were able to accurately interpret 75% of basic radiology images. In an effort to improve patient care, programs should consider integrating radiological education during surgical training.


Subject(s)
Clinical Competence , Diagnostic Imaging , Internship and Residency , Education, Medical, Graduate , Female , General Surgery/education , Humans , Male
8.
Bull Emerg Trauma ; 4(4): 244-247, 2016 10.
Article in English | MEDLINE | ID: mdl-27878132

ABSTRACT

The majority of blunt trauma is secondary to motor vehicle crashes,especially in those wearing seatbelts or sitting in the front or passenger seat location.Hollow viscus gastrointestinal injuries occur more frequently in small bowel, followed by colorectal, duodenum, stomach and appendix. A 25-year-old male presents after being involved in a motor vehicle accident. Initialworkup was significant for moderate amount of pelvic free fluid and curvilinear,cysticlike structures in the pelvis. He subsequently developed peritonitis and underwentdiagnostic laparoscopy, which revealed multiple cystic nodules arising from theperitoneum. Pathology demonstrated benign cystic mesothelioma (BCM). BCM is a very rarecondition of mesotheliallined, variably sized, fluidfilled cysts that arises from theserous, pericardial or peritoneal lining. Due to the scarcity of cases, its management and prognosis are not fully established. This singular case highlights the necessity for a clinician to have a widedifferential forunusual causes of free pelvic fluid after blunt abdominaltrauma.

9.
Ann Vasc Surg ; 35: 38-45, 2016 Aug.
Article in English | MEDLINE | ID: mdl-27263811

ABSTRACT

BACKGROUND: Operative management of traumatic shank vascular injuries (SVI) evolved significantly in the past few decades, thereby leading to a dramatic decrease in amputation rates. However, there is still controversy regarding the minimum number of patent shank arteries sufficient for limb salvage. METHODS: Between January 2006 and September 2011, 191 adult trauma patients presented to an urban level I trauma center in Miami, Florida, with traumatic lower extremity vascular injuries. Variables collected included age, gender, mechanism of injury, and clinical status at presentation. Surgical data included vessel injury, technical aspects of repair, associated complications, and outcomes. RESULTS: A total of 48 (25.1%) patients were identified comprising 66 traumatic shank arterial injuries. Mean age was 38.2 ± 13.4 years, and the majority of patients were men (40 patients, 83.3%) presenting with blunt injuries (35 patients, 72.9%). Ligation was performed in 38 injured arteries (57.6%) and no vascular intervention was required in 20% of the patients. Vascular reconstruction was performed in only 6 patients (9.1%): 4 (6.1%) with concurrent popliteal trauma, 1 (1.5%) isolated anterior tibial, and 1 (1.5%) 3-vessel injury. Autogenous venous interposition conduit and polytetrafluoroethylene grafting were performed in 5 (7.6%) and 1 (1.5%) patient, respectively. All amputations (8 patients, 16.7%) occurred in blunt trauma patients presenting with unsalvageable limbs. The overall mortality rate in this series was 2.1%. CONCLUSIONS: Civilian shank arterial injuries are associated with acceptable rates of limb loss. Patients with a single-vessel patent inflow did not require vascular reconstruction in this series. Arterial reconstruction may no longer be determinant for successful management of isolated and double arterial SVI, whereas it is yet essential in the presence of 3-vessel or concurrent above-the-knee vascular injuries. Further investigation including larger number of patients is still warranted to define the role of conservative management in these complex injuries.


Subject(s)
Amputation, Surgical , Arteries/surgery , Lower Extremity/blood supply , Plastic Surgery Procedures , Vascular Surgical Procedures , Vascular System Injuries/surgery , Adolescent , Adult , Aged , Amputation, Surgical/adverse effects , Amputation, Surgical/mortality , Arteries/diagnostic imaging , Arteries/injuries , Blood Vessel Prosthesis Implantation , Female , Florida , Humans , Ligation , Limb Salvage , Male , Middle Aged , Plastic Surgery Procedures/adverse effects , Plastic Surgery Procedures/mortality , Retrospective Studies , Risk Factors , Trauma Centers , Treatment Outcome , Vascular Surgical Procedures/adverse effects , Vascular Surgical Procedures/mortality , Vascular System Injuries/diagnostic imaging , Vascular System Injuries/mortality , Veins/transplantation , Young Adult
10.
Ann Surg Oncol ; 23(6): 1838-44, 2016 06.
Article in English | MEDLINE | ID: mdl-26832884

ABSTRACT

BACKGROUND: Occult breast cancer (OBC) represents a rare clinical entity and poses a therapeutic dilemma. Due to limited experience, no optimal treatment approaches have yet been established. METHODS: A meta-analysis was performed using MEDLINE and EMBASE databases to identify all studies investigating the surgical options for OBC: (1) axillary lymph node dissection (ALND) with radiotherapy (XRT); (2) ALND with mastectomy; and (3) ALND alone. Comparative studies including nonoperative management (observation or XRT alone) were excluded. The primary endpoints were locoregional recurrence, distant metastasis, and mortality rates. RESULTS: The literature search yielded 42 publications. Seven studies met the inclusion criteria comprising 241 patients. Among these patients, 94 (39 %) underwent ALND with XRT, 112 (46.5 %) underwent mastectomy, and 35 (14.5 %) underwent ALND alone. Mean follow-up was 61.8 ± 16.2 months (range 5-396 months). Locoregional recurrence (12.7 vs. 9.8 %), distant metastasis (7.2 vs. 12.7 %), and mortality rates (9.5 vs. 17.9 %) were similar between ALND with XRT and mastectomy. ALND with XRT was superior to ALND alone regarding locoregional recurrence (12.7 vs. 34.3 %, p < 0.01) and there was a trend toward improved mortality rates (9.5 vs. 31.4 %, p = 0.09). CONCLUSIONS: There was no difference in survival outcomes between mastectomy and ALND with XRT of patients with OBC. Radiotherapy improves locoregional recurrence and, possibly mortality rates of patients undergoing ALND. Based on this meta-analysis, combined ALND and radiation therapy may appear as the optimal surgical approach in these patients.


Subject(s)
Breast Neoplasms/surgery , Mastectomy , Axilla , Female , Humans , Lymph Node Excision , Lymphatic Metastasis , Prognosis
11.
Surg Oncol ; 24(2): 117-22, 2015 Jun.
Article in English | MEDLINE | ID: mdl-25956302

ABSTRACT

INTRODUCTION: Consensus guidelines have recommended total thyroidectomy for papillary thyroid carcinoma (PTC) > 1 cm. However, the optimal surgical approach for small and unilateral (≤1 cm) PTC remains controversial. METHODS: A meta-analysis was performed using MEDLINE and EMBASE databases to identify all studies investigating at thyroid surgery options, total thyroidectomy (TT) versus thyroid lobectomy (TL), for PTC ≤ 1 cm. The primary endpoints were locoregional recurrence and mortality rates. RESULTS: The initial literature search identified 305 publications (1980-2014). Six studies met the inclusion criteria comprising 2939 patients (2002-2013). Among these patients, 2134 (72.6%) underwent TT and 805 (27.4%) underwent TL. Mean follow-up was 10.9 ± 3.4 years (range, 1 month to 54 years). Overall, the recurrence rate was 5.4%: 4.4% in the TT group and 8.3% in the TL group (p < 0.001; RR 0.50, 95% CI 0.37-0.67). The mortality rates were 0.3% (8 cases) versus 1.1% (9 cases) in TT and TL groups, respectively (p = 0.14; RR 0.43, 95% CI 0.17-1.09). CONCLUSION: TT was associated with lower recurrence rates, possibly due to a more complete nodal dissection of the central neck compartment at the time of initial surgery. Based on these data, it is unclear to establish a definitive correlation between the extent of thyroid resection and long-term survival rates due to the small number of mortality events. However, there is a trend toward lower mortality rates in the TT group. Other factors need to be taken into consideration while planning thyroid resection for small PTC, such as multifocality, locoregional involvement, mode of presentation and age at diagnosis. Refinement of current guidelines for the optimal surgical management of PTC <1 cm may be warranted.


Subject(s)
Carcinoma/surgery , Thyroid Neoplasms/surgery , Thyroidectomy/methods , Adult , Aged , Carcinoma/mortality , Carcinoma, Papillary , Female , Follow-Up Studies , Humans , Male , Middle Aged , Neoplasm Recurrence, Local/mortality , Neoplasm Recurrence, Local/surgery , Thyroid Cancer, Papillary , Thyroid Neoplasms/mortality , Thyroidectomy/mortality , Treatment Outcome
12.
Int J Surg ; 18: 136-41, 2015 Jun.
Article in English | MEDLINE | ID: mdl-25924816

ABSTRACT

INTRODUCTION: Popliteal vascular trauma remains a challenging entity, and carries the greatest risk of limb loss among the lower extremity vascular injuries. Operative management of traumatic popliteal vascular injuries continues to evolve. We aim at describing our experience with such complex injuries, with associated patterns of injury, diagnostic and therapeutic challenges, and outcomes. METHODS: From January 2006 to September 2011, 191 adult trauma patients presented to an urban level I trauma center in Miami, Florida with traumatic lower extremity vascular injuries. Variables collected included age, gender, mechanism of injury, and clinical status at presentation. Surgical data included vessel injury, technical aspects of repair, associated complications and outcomes. RESULTS: Forty-seven (24.6%) patients were diagnosed with traumatic popliteal vascular injuries. Mean age was 38.1 ± 16.1 years, and the majority of patients were males (43 patients, 91.4%). There were 21 (44.7%) penetrating injuries, and 26 (55.3%) blunt injuries. Vascular repair with saphenous venous interposition graft and PTFE (polytetrafluoroethylene) grafting were performed in 36 (70.7%) and 2 (3.9%) patients, respectively. Blunt popliteal injuries were significantly more associated with major tissue loss, and length of hospital and intensive care unit (ICU) stays. The risk for amputation is increased with longer ICU stays and the use of PTFE grafting for vascular repair. The overall mortality rate in this series was 8.5%. CONCLUSIONS: Blunt popliteal vascular injuries are associated with increased morbidity compared to penetrating trauma. Early restoration of blood perfusion, frequent use of interposition grafts with autogenous saphenous vein, and liberal use of fasciotomies play important role to achieve acceptable outcomes.


Subject(s)
Popliteal Artery/injuries , Popliteal Vein/injuries , Wounds, Nonpenetrating/surgery , Wounds, Penetrating/surgery , Adult , Amputation, Surgical , Female , Florida/epidemiology , Humans , Male , Middle Aged , Polytetrafluoroethylene/therapeutic use , Retrospective Studies , Saphenous Vein/surgery , Trauma Centers , Vascular Surgical Procedures/methods , Vascular Surgical Procedures/mortality , Wounds, Nonpenetrating/epidemiology , Wounds, Penetrating/epidemiology
13.
Am Surg ; 81(1): 86-91, 2015 Jan.
Article in English | MEDLINE | ID: mdl-25569071

ABSTRACT

Femoral vessel injuries are a familiar injury treated in busy urban trauma centers. The majority of peripheral vascular injuries to the lower extremity occur most commonly to the femoral vessels. The increasing incidence of civilian violence provides an opportunity to perform a comprehensive review and management of these injuries.


Subject(s)
Femur/blood supply , Femur/injuries , Vascular Surgical Procedures , Vascular System Injuries/surgery , Adolescent , Adult , Aged , Aged, 80 and over , Female , Florida/epidemiology , Humans , Limb Salvage , Male , Middle Aged , Retrospective Studies , Treatment Outcome , Vascular System Injuries/diagnosis , Vascular System Injuries/epidemiology
14.
Ann Vasc Surg ; 29(2): 366.e5-366.e10, 2015 Feb.
Article in English | MEDLINE | ID: mdl-25463326

ABSTRACT

Popliteal vascular trauma remains a challenging entity and carries the greatest risk of limb loss among the lower extremity vascular injuries. Operative management of patients presenting with traumatic popliteal vascular injuries continues to evolve. We present a case of successful endovascular repair with stent grafting of an acute blunt popliteal artery injury. Endovascular repair of traumatic popliteal vascular injuries appears as an attractive alternative to surgical repair in a very selective group of patients. Further investigation is still needed to define the safety and feasibility of endovascular approach in the management of traumatic popliteal vascular injuries.


Subject(s)
Fractures, Bone/diagnostic imaging , Knee Injuries/diagnostic imaging , Popliteal Artery/surgery , Vascular System Injuries/surgery , Wounds, Nonpenetrating/surgery , Blood Vessel Prosthesis , Blood Vessel Prosthesis Implantation , Endovascular Procedures , Female , Fibula/injuries , Fractures, Bone/complications , Humans , Knee Dislocation/complications , Knee Dislocation/diagnostic imaging , Knee Injuries/complications , Lower Extremity/blood supply , Middle Aged , Popliteal Artery/diagnostic imaging , Popliteal Artery/injuries , Radiography , Stents , Vascular System Injuries/diagnosis , Wounds, Nonpenetrating/diagnosis
16.
World J Hepatol ; 6(7): 453-63, 2014 Jul 27.
Article in English | MEDLINE | ID: mdl-25067997

ABSTRACT

The approach for colorectal hepatic metastasis has advanced tremendously over the past decade. Multidrug chemotherapy regimens have been successfully introduced with improved outcomes. Concurrently, adjunct multimodal therapies have improved survival rates, and increased the number of patients eligible for curative liver resection. Herein, we described major advancements of surgical and oncologic management of such lesions, thereby discussing modern chemotherapeutic regimens, adjunct therapies and surgical aspects of liver resection.

17.
J Trauma Acute Care Surg ; 76(6): 1386-9, 2014 Jun.
Article in English | MEDLINE | ID: mdl-24854305

ABSTRACT

BACKGROUND: Traumatic vascular injuries of the lower extremity in the pediatric population are rare but can result in significant morbidity. We aimed at describing our experience with such complex injuries, with associated patterns of injury, diagnostic and therapeutic challenges, and outcomes. METHODS: From January 2006 to December 2011, 2,844 pediatric trauma patients presented at the Ryder Trauma Center, an urban Level I trauma center in Miami, Florida. Among them, 18 patients (0.6%) were evaluated for lower extremity traumatic vascular injuries. Variables collected included age, sex, mechanism of injury, and clinical status at presentation. Surgical data included vessel injury, technical aspects of repair, associated complications, and outcomes. RESULTS: Mean (SD) age was ± 14.7 (2.6) years (range, 6-17 years), with 17 males (94.4%). Of the 18 traumatic pediatric patients, 32 vascular injuries were identified. All arterial injuries underwent definitive operative repair. Primary repair was performed in two patients (11.1%), six (33.3%) required saphenous vein interposition grafting as initial procedure, and eight (44.4%) underwent polytetrafluoroethylene grafting. Ligation was performed in major venous injuries and deep profunda branches. The overall survival in this series was 94.4%. CONCLUSION: Peripheral vascular injuries of the lower extremity in the pediatric population can result in acceptable outcomes if managed early and aggressively. Surgical principles of vascular surgery are similar to those applied to an adult. We recommend that these injuries should be managed in a tertiary specialized center with a multidisciplinary team of trauma surgeons, and pediatricians, which can potentially decrease morbidity and mortality. LEVEL OF EVIDENCE: Epidemiologic study, level III.


Subject(s)
Arteries/injuries , Hospitals, Pediatric , Leg/blood supply , Trauma Centers , Vascular Surgical Procedures/methods , Vascular System Injuries/surgery , Veins/injuries , Adolescent , Angiography , Arteries/surgery , Child , Female , Florida/epidemiology , Follow-Up Studies , Humans , Incidence , Male , Prognosis , Retrospective Studies , Survival Rate/trends , Tomography, X-Ray Computed , Trauma Severity Indices , Ultrasonography, Doppler, Duplex , Vascular System Injuries/diagnosis , Vascular System Injuries/epidemiology , Veins/surgery
18.
J Burn Care Res ; 35(6): e431-5, 2014.
Article in English | MEDLINE | ID: mdl-24476990

ABSTRACT

Toxic epidermal necrolysis (TEN) is a rare complication after allogeneic hematopoietic stem-cell transplantation and carries high mortality rates. Graft-vs-host disease (GVHD) is also a life-threatening complication, and potentially indistinguishable from TEN because of similar clinical symptoms. However, current therapeutic recommendations differ between these two conditions, thereby posing a diagnostic dilemma. The authors, herein, present a complicated postoperative course after bone marrow transplantation with concurrent gastrointestinal and hepatic GVHD, and extensive epidermolytic disease compatible with both severe cutaneous GVHD and TEN. An early consult to a specialized burn service, and prompt transfer to a burn intensive care unit with extensive supportive care and nursing are of paramount importance in the management of immunosuppressed patients with TEN. Better understanding of the pathogenesis of TEN and GVHD after hematopoietic stem-cell transplantation, further treatment strategies, and more advanced diagnostic techniques are still needed to achieve acceptable mortality rates.


Subject(s)
Hematopoietic Stem Cell Transplantation/adverse effects , Lymphoma, Non-Hodgkin/therapy , Stevens-Johnson Syndrome/diagnosis , Stevens-Johnson Syndrome/etiology , Diagnosis, Differential , Fatal Outcome , Female , Graft vs Host Disease/diagnosis , Humans , Stevens-Johnson Syndrome/therapy , Transplantation, Homologous , Young Adult
19.
Am Surg ; 80(1): 66-71, 2014 Jan.
Article in English | MEDLINE | ID: mdl-24401517

ABSTRACT

Iatrogenic biliary injury is the most significant complication after laparoscopic cholecystectomy. We present our experience with an alternative diagnostic approach using transcatheter cholangiography (TCC) through a Jackson-Pratt (JP) drain and discuss potential benefits and limitations of the technique. From March 2002 to February 2012, 40 patients with major postoperative biliary injury underwent biliary reconstruction at our institution. Mean age was 51.7 ± 18.1 years (range, 19 to 86 years) with 30 (75%) females. Seventeen (42.5%) injuries were detected intraoperatively and in 13 (32.5%) cases, JP drains were placed for biliary drainage. Lesions were classified according to Bismuth grade: I (10 patients [25%]), II (10 patients [25%]), III (six patients [15%]), IV (10 patients [25%]), and V (four patients [10%]). TCC was performed in seven patients with JP drains (53.8%). It fully defined the injury site in three cases of limited magnetic resonance cholangiopancreatography (MRCP) such as common hepatic duct and common bile duct leaks and in four cases (57.1%) that endoscopic retrograde cholangiopancreatography (ERCP) was limited as a result of clipping of the distal common bile duct. TCC showed promising results in cases of limited MRCP and ERCP such as fistulous orifices or leakage. It may represent an alternative adjunct in the diagnostic armamentarium of complex biliary injuries.


Subject(s)
Bile Ducts/injuries , Catheters, Indwelling , Cholangiography/methods , Cholecystectomy, Laparoscopic/adverse effects , Drainage/instrumentation , Adult , Aged , Aged, 80 and over , Anastomosis, Surgical , Bile Ducts/surgery , Cholangiopancreatography, Endoscopic Retrograde , Cholangiopancreatography, Magnetic Resonance , Cholecystectomy, Laparoscopic/instrumentation , Drainage/methods , Female , Humans , Jejunum/surgery , Liver/surgery , Male , Middle Aged , Retrospective Studies , Treatment Outcome
20.
Hepatogastroenterology ; 61(136): 2163-6, 2014.
Article in English | MEDLINE | ID: mdl-25699342

ABSTRACT

BACKGROUND/AIMS: Major iatrogenic biliary injury is a potentially life-threatening complication after laparoscopic cholecystectomy. Early diagnosis is essential to improve outcomes, however, to date, there is no consensus regarding the best imaging approach for preoperative assessment of these injuries. METHODOLOGY: From March 2002 to February 2012, 40 patients with postoperative major biliary injury underwent biliary reconstruction at our Institution. Mean age was 51.7 ± 18.1 years (19-86) with 30 (75%) females. Magnetic resonance cholangiopancreatography (MRCP) were compared with different diagnostic modalities and definitive intraoperative findings. RESULTS: Of 40 patients, 10 (25%) had Bismuth type I, 10 (25%) Bismuth type II, 6 (15%) Bismuth type III injury, 10 (25%) Bismuth type IV and, 4 (10%) Bismuth type V. MRCP has similar accuracy to define injury site, but is superior in delineating proximal ductal anatomy that was often not visualized with endoscopic retrograde cholangiopancreatography (ERCP). CONCLUSION: MRCP is a reliable, accurate and readily available diagnostic tool to assess complex biliary injuries. It provides adequate visualization of the proximal and distal biliary trees and may be considered as first-line test in the management of major iatrogenic biliary injuries. Revision of current guidelines for diagnostic approach of this condition is warranted.


Subject(s)
Cholangiopancreatography, Magnetic Resonance/methods , Cholecystectomy, Laparoscopic/adverse effects , Postoperative Complications/surgery , Preoperative Care , Adult , Aged , Aged, 80 and over , Cholangiopancreatography, Endoscopic Retrograde , Female , Humans , Male , Middle Aged
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