ABSTRACT
OBJECTIVES: to identify the relationship between Helicobacter pylori infection and various factors that have been described in other studies in the general adult population in the province of Ourense. MATERIAL AND METHODS: three hundred and eighty-three participants were enrolled in a study on the prevalence of Helicobacter pylori infection. All participants filled in a questionnaire under supervision, and the data obtained were examined by means of a univariate analysis. The odds ratio corresponding to each variable studied was calculated with their corresponding 95% confidence intervals. Furthermore, a multivariate analysis was performed. RESULTS: the univariate analysis revealed an association between infection and: age, place of residence during childhood, current social status based on the head of the family s profession, current blue collar/white collar profession of the head of the family, sharing a bedroom during childhood, type of drinking water, and contact with animals during childhood. No association was found with respect to the presence of dyspeptic symptoms. The multivariate analysis disclosed that only age is an independent risk factor associated with infection. CONCLUSION: age has been identified as the only independent risk factor associated with Helicobacter pylori infection in this population-based study. The univariate analysis has detected other factors. No association has been identified with respect to dyspeptic symptoms.
Subject(s)
Helicobacter Infections/epidemiology , Helicobacter pylori , Adolescent , Adult , Age Factors , Aged , Education , Female , Humans , Male , Middle Aged , Risk Factors , Sex Factors , Social Class , Socioeconomic Factors , Spain/epidemiology , Surveys and QuestionnairesABSTRACT
OBJECTIVES: to determine the prevalence of Helicobacter pylori infection in the general adult population of the province of Ourense. MATERIAL AND METHODS: a cross-sectional study was carried out with a randomly selected populational sample. The diagnosis of Helicobacter pylori infection was reached using the 13C-urea breath test. RESULTS: three hundred and eighty-three subjects were studied, with a prevalence rate of 69.1% (95% CI: 61.7-75.1%); 69.8% (95% CI: 63.2-76.6%) in males and 68.4% (95% CI: 61.5-75.4%) in females (difference not statistically significant). Prevalence increases with age up to a maximum of 88.4% in the 45-54 years age group, and decreases thereafter to a rate of 57.1% in individuals over the age of 84 years. CONCLUSION: this study reveals that the prevalence rate of Helicobacter pylori infection is high in the general adult population of the province of Ourense. It increases with age until it peaks in the group of middle-aged individuals and is similar in both sexes.
Subject(s)
Helicobacter Infections/epidemiology , Helicobacter pylori , Adolescent , Adult , Aged , Aged, 80 and over , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Prevalence , Spain/epidemiologyABSTRACT
Objetivos: identificar en la población general adulta de la provinciade Ourense, la relación entre la infección por Helicobacterpylori y diversos factores que se han descrito en otros estudios.Material y métodos: se han incluido los 383 participantesen un estudio de prevalencia de la infección por Helicobacter pylori.Todos han completado un cuestionario bajo supervisión y losdatos se han examinado mediante análisis univariante. Se han calculadolas odds ratio correspondientes a cada variable estudiada,con sus intervalos de confianza al 95%. Además, se ha efectuadoun análisis multivariante.Resultados: el análisis univariante demuestra asociación dela infección con: edad, lugar de residencia en la infancia, clasesocial actual por la profesión del cabeza de familia, profesiónno manual/manual del cabeza de familia actual, compartir dormitorioen la infancia, tipo de agua de consumo y el contactocon animales en la infancia. No se ha encontrado asociacióncon la presencia de síntomas dispépticos. El análisis multivarianteha mostrado que solamente la edad es un factor de riesgoindependiente asociado a la infección.Conclusión: en este estudio de base poblacional la edad es elúnico factor de riesgo independiente que se ha identificado asociadoa la infección por Helicobacter pylori. En el análisis univariantese han identificado otros factores. No se demuestra asociacióncon síntomas dispépticos
Objectives: to identify the relationship between Helicobacterpylori infection and various factors that have been described inother studies in the general adult population in the province ofOurense.Material and methods: three hundred and eighty-three participantswere enrolled in a study on the prevalence of Helicobacterpylori infection. All participants filled in a questionnaire undersupervision, and the data obtained were examined by means of aunivariate analysis. The odds ratio corresponding to each variablestudied was calculated with their corresponding 95% confidenceintervals. Furthermore, a multivariate analysis was performed.Results: the univariate analysis revealed an association betweeninfection and: age, place of residence during childhood,current social status based on the head of the familys profession,current blue collar/white collar profession of the head of the family,sharing a bedroom during childhood, type of drinking water,and contact with animals during childhood. No association wasfound with respect to the presence of dyspeptic symptoms. Themultivariate analysis disclosed that only age is an independent riskfactor associated with infection.Conclusion: age has been identified as the only independentrisk factor associated with Helicobacter pylori infection in thispopulation-based study. The univariate analysis has detected otherfactors. No association has been identified with respect to dyspepticsymptoms
Subject(s)
Male , Female , Adult , Aged , Adolescent , Middle Aged , Humans , Helicobacter Infections/epidemiology , Helicobacter pylori , Socioeconomic Factors , Risk Factors , Surveys and Questionnaires , Social Class , Spain/epidemiologyABSTRACT
Objetivos: conocer la prevalencia de la infección por Helicobacterpylori en la población general adulta de la provincia deOurense.Material y métodos: se ha realizado un estudio transversalcon una muestra poblacional seleccionada al azar. El diagnósticode la infección por Helicobacter pylori se ha realizado mediantela prueba de aliento con 13C-urea.Resultados: se han estudiado 383 sujetos, obteniéndoseuna prevalencia del 69,1% (IC 95%: 61,7-75,1%), del 69,8%(IC 95%: 63,2-76,6%) en hombres y del 68,4% (IC 95%:61,5-75,4%) en mujeres, diferencia no significativa. La prevalenciaaumenta en relación con la edad, hasta un máximo del88,4% en el grupo de 45-54 años, y decrece en los grupos siguienteshasta alcanzar el 57,1% en los individuos de más de84 años.Conclusión: este estudio muestra que la prevalencia de la infecciónpor Helicobacter pylori es elevada en la población generaladulta de la provincia de Ourense. Aumenta con la edad hastaalcanzar un máximo en el grupo de edad media, y es similar enambos sexos
Objectives: to determine the prevalence of Helicobacter pyloriinfection in the general adult population of the province ofOurense.Material and methods: a cross-sectional study was carriedout with a randomly selected populational sample. The diagnosisof Helicobacter pylori infection was reached using the 13C-ureabreath test.Results: three hundred and eighty-three subjects were studied,with a prevalence rate of 69.1% (95% CI: 61.7-75.1%);69.8% (95% CI: 63.2-76.6%) in males and 68.4% (95% CI:61.5-75.4%) in females (difference not statistically significant).Prevalence increases with age up to a maximum of 88.4% in the45-54 years age group, and decreases thereafter to a rate of57.1% in individuals over the age of 84 years.Conclusion: this study reveals that the prevalence rate of Helicobacterpylori infection is high in the general adult populationof the province of Ourense. It increases with age until it peaks inthe group of middle-aged individuals and is similar in both sexes
Subject(s)
Male , Female , Adult , Aged , Adolescent , Middle Aged , Aged, 80 and over , Humans , Helicobacter Infections/epidemiology , Helicobacter pylori , Cross-Sectional Studies , Prevalence , Spain/epidemiologyABSTRACT
OBJECTIVE: The analysis of the endoscopic and histological characteristics of all the gastric epithelial polyps diagnosed through endoscopy in our service during a period of 5 years, and the evaluation of the usefulness of the endoscopic monitoring after polypectomy. PATIENTS AND METHODS: Between January 1995 and January 2000 5,314 high digestive system endoscopies were carried out in the Gastroenterology Service of the Santa María Madre Hospital. Sixty-four gastric epithelial polyps were detected in 18 patients (10 men and 8 women) with a median age of 61.7 years. RESULTS: Sixty-three polyps were removed through endoscopic polypectomy, and one was biopsied because of its size (5 cm), 30 (46.87%) were hyperplastic polyps, 24 (37.5%) presented normal histological characteristics, 8 (12.5%) were adenomas and 2 (3.12%) were polypoid adenocarcinomas. 56.2% measured less than 6 mm and only 6.2% measured more than 11 mm. No patient presented simultaenous gastric adenocarcinoma. Only one complication was observed after the polypectomy, a hemorrhage that was treated successfully with local injection of adrenaline. During the follow-up no case of cancer was detected and the recurrence of the polyp was observed in 2/8 patients with adenoma. CONCLUSIONS: Gastric epithelial polyps are infrequent (0.33% gastroscopies); most of them (93.75%) measure less than 1 cm and they can be removed through endoscopy with safety. In our series, the most frequent histological type was the hyperplastic polyp (43.75%); polypoid adenocarcinoma constituted 3.12% of the cases, one of them with less than 6 mm. Endoscopic follow-up is considered absolutely essential after the polypectomy, especially in adenomatous polyps.
