Factors associated with the absence of postpartum consultations in a high-risk population.

Objective: To assess the rate of missed postpartum appointments at a referral center for high-risk pregnancy and compare puerperal women who did and did not attend these appointments to identify related factors. Methods: This was a retrospective cross-sectional study with all women scheduled for postpartum consultations at a high-risk obstetrics service in 2018. The variables selected to compare women were personal, obstetric, and perinatal. The variables of interest were obtained from the hospital's electronic medical records. Statistical analyses were performed using the Chi-square, Fisher's exact, or Mann-Whitney tests. For the variable of the interbirth interval, a receiver operating characteristic curve (ROC) was used to best discriminate whether or not patients attended the postpartum consultation. The significance level for the statistical tests was 5%. Results: A total of 1,629 women scheduled for postpartum consultations in 2018 were included. The rate of missing the postpartum consultation was 34.8%. A shorter interbirth interval (p = 0.039), previous use of psychoactive substances (p = 0.027), current or former smoking (p = 0.003), and multiparity (p < 0.001) were associated with non-attendance. Conclusion: This study showed a high rate of postpartum appointment non-attendance. This is particularly relevant because it was demonstrated in a high-risk obstetric service linked to clinical severity or social vulnerability cases. This highlights the need for new approaches to puerperal women before hospital discharge and new tools to increase adherence to postpartum consultations, especially for multiparous women.

Factors associated with the absence of postpartum consultations in a high-risk population

Abstract Objective: To assess the rate of missed postpartum appointments at a referral center for high-risk pregnancy and compare puerperal women who did and did not attend these appointments to identify related factors. Methods: This was a retrospective cross-sectional study with all women scheduled for postpartum consultations at a high-risk obstetrics service in 2018. The variables selected to compare women were personal, obstetric, and perinatal. The variables of interest were obtained from the hospital's electronic medical records. Statistical analyses were performed using the Chi-square, Fisher's exact, or Mann-Whitney tests. For the variable of the interbirth interval, a receiver operating characteristic curve (ROC) was used to best discriminate whether or not patients attended the postpartum consultation. The significance level for the statistical tests was 5%. Results: A total of 1,629 women scheduled for postpartum consultations in 2018 were included. The rate of missing the postpartum consultation was 34.8%. A shorter interbirth interval (p = 0.039), previous use of psychoactive substances (p = 0.027), current or former smoking (p = 0.003), and multiparity (p < 0.001) were associated with non-attendance. Conclusion: This study showed a high rate of postpartum appointment non-attendance. This is particularly relevant because it was demonstrated in a high-risk obstetric service linked to clinical severity or social vulnerability cases. This highlights the need for new approaches to puerperal women before hospital discharge and new tools to increase adherence to postpartum consultations, especially for multiparous women.

Pelvic floor disorders in women with premature ovarian insufficiency: a cross-sectional study.

OBJECTIVES: This study aimed to investigate the prevalence of self-reported main pelvic floor disorders (PFD) (urinary incontinence [UI], pelvic organ prolapse [POP], and fecal incontinence [FI]) and its associated factors in women with premature ovarian insufficiency (POI) and a control group. METHODS: This was a cross-sectional study wherein two groups were interviewed from August, 2017 to November, 2018-women with POI (n = 150) and a control group matched for age and body weight (n = 150). Sociodemographic variables and two questionnaires validated in Brazilian Portuguese language for PFD (Kings Health Questionnaire [KHQ] and Pelvic Floor Distress Inventory-20 [PFDI-20]) were used. Laycock's power, endurance, repetitions, fast contractions, every contraction timed (PERFECT) scale for pelvic floor muscle assessment was used in both groups. RESULTS: The prevalence of self-reported UI was 27.33% and 37.33% for POI and control groups (P > 0.05), respectively. There was no perceived difference regarding the prevalence of POP (9.33% POI group vs 8% control group; P = 0.682) and FI (8% POI vs 4% control group; P = 0.145). The P (power) (P = 0.46), E (endurance) (P = 0.91), R (repetitions) (P = 0.88), and F (fast contractions) (P = 0.19) values were statistically similar in both the groups. Multivariate analysis (n = 141) showed that higher weight (odds ratio [OR] 1.047 [1.018-1.076]; P < 0.001) and gravidity rates (OR 1.627 [1.169-2.266]; P < 0.01) were risk factors for UI and higher weight (OR 1.046 [1.010-1.084]; P = 0.01), and presence of comorbidities (OR 8.75 [1.07-71.44]; P < 0.01) were risk factors for POP in the POI group; there was no variable that was associated with FI. CONCLUSIONS: Women with POI did not have significant differences when compared with the control group regarding the prevalence of PFD and pelvic floor muscle assessment. Having higher weight and gravidity rates were associated with self-reported UI, while the presence of comorbidities and higher weight were risk factors for POP in the POI group. : Video Summary:http://links.lww.com/MENO/A555.

Incidence rates and temporal trends of cervical cancer relating to opportunistic screening in two developed metropolitan regions of Brazil: a population-based cohort study.

BACKGROUND: Brazilian opportunistic screening programs for cervical cancer have limited impact. In the regions of two cities (Campinas and Curitiba) with high human development indices, consistent information from 96-97% of all cervical cancer cases managed within the public healthcare system is available. OBJECTIVE: To estimate the incidence rate (IR) and temporal trends in these regions, covering 2001-2012. DESIGN AND SETTING: A population-based cohort study was conducted under the assumption that all cervical cancer cases were managed in cancer referral center hospitals. METHODS: 3,364 records (1,646 from Campinas; 1,718 from Curitiba) were analyzed to provide estimates of IR, age-standardized IR (ASR) and cervical cancer trends (shown per 100,000 women/year). Longitudinal patterns were analyzed using linear regression and shown as annual percentage change (APC); P < 0.05 for significance. RESULTS: Annual IR and ASR estimates for cervical cancer ranged from 3.8 to 8.0 over 2001-2012, decreasing over more recent years, and were similar for the two regions. The age-specific IR was about 50% lower among women aged 45 years or older (IR-2001/IR-2012: Campinas = 14.8/8.0; Curitiba = 18.7/8.3; P < 0.001). There was an increasing APC trend in Campinas among women aged 15-24 years, and a decreasing IR trend for squamous-cell histology in both regions (P < 0.05). CONCLUSION: Cervical cancer incidence estimates showed slowly decreasing trends in both regions, most evidently for women aged 45 years or older and for squamous-cell histology. These findings reflect the opportunistic nature of the population screening program, despite the comparatively high economic development level in the two regions.

Influência de Políticas de Ação Afirmativa no Perfil Sociodemográfico de Estudantes de Medicina de Universidade Brasileira / Influence of Affirmative Action Policies on Socio Demographic Profile of Medical Students from a Brazilian University

RESUMO A adoção de políticas públicas de inclusão pela Universidade Estadual de Campinas (Unicamp) desde o processo seletivo de 2005, atrelada às modificações nos vestibulares de 2014 e, mais recentemente, no de 2016, possivelmente trouxe grandes mudanças no perfil do estudante de Medicina dessa universidade. Desse modo, o objetivo do presente estudo é avaliar o perfil sociodemográfico desses acadêmicos, bem como suas pretensões na escolha da carreira médica e da futura especialidade. O estudo de corte transversal foi realizado com 290 acadêmicos do primeiro, terceiro e sexto ano da graduação médica da Unicamp por meio de um questionário anônimo aplicado após aprovação do Comitê de Ética em Pesquisa. Houve coleta de dados sociodemográficos, além dos fatores de influência para a escolha da profissão e da especialidade médica. A análise dos dados revelou uma amostra com idade média de 20-24 anos, predominantemente composta por mulheres (63,2%), da etnia branca (77,5%), procedentes do Estado de São Paulo (84,8%) e de regiões interioranas (62,3%). Para o primeiro ano, houve presença de negros (6,6%) e diferença estatística para pardos (22,6%), comparativa com o terceiro e sexto ano, egressos de ensino fundamental (42,5%) e médio (73,6%) públicos, com menor escolaridade materna (ensino médio) e renda familiar inferior (p < 0,001). Por sua vez, o terceiro e sexto ano eram compostos majoritariamente por alunos brancos (76,7% e 90,3%, respectivamente), oriundos de escola privada no ensino fundamental e médio, com maior escolaridade materna (ensino superior ou pós-graduação) e renda familiar mais elevada. Ainda, verificou-se variação das opções de especialidade ao longo do curso (p < 0,001). No primeiro ano, as especialidades mais pretendidas foram Cirurgia/Ortopedia (37,7%), Clínica Médica/Neurologia (23,6%) e Psiquiatria (11,3%). Para o terceiro ano, as especialidades mais desejadas foram Clínica Médica/Neurologia (40%), Cirurgia/Ortopedia (13,4%) e Ginecologia/Obstetrícia (13,3%). Entre os alunos do sexto ano, as especialidades mais escolhidas foram Clínica Médica/Neurologia (24,5%), Ginecologia/Obstetrícia (20,2%) e Cirurgia/Ortopedia (17%). Acadêmicos do primeiro ano também apresentaram diferentes aspirações abrangendo o local de trabalho futuro, com mais desejo de atuar somente no SUS ou em programas internacionais. Nesse contexto, os resultados apontam que a política de bonificação da Unicamp e suas alterações ao longo do tempo, em especial no vestibular de 2016, mostraram-se efetivas em democratizar o acesso à graduação médica, com maior pluralidade demográfica, social, econômica e étnica atreladas a variações na escolha da carreira e da especialidade médica ao longo das turmas analisadas.

ABSTRACT Affirmative action policies adopted by University of Campinas (Unicamp) in 2005 entrance exams, added to 2014 modifications, and more recently in 2016, lead to a big profile change of University of Campinas medical students. Therefore, this paper aims to describe academics' sociodemographic profile, as well as their aspirations in choice of medical career and future specialty. The cross-sectional study included 290 undergraduate years 1, 3 and 6 (Y1, Y3 and Y6) medical students from Unicamp who answered an anonymous questionnaire applied after approval by the Institutional Review Board. Socio demographic data and factors potentially influencing decisions on medical career and specialty choices were analyzed. Data analysis showed a sample composed mostly of white (77.5%), female (63.2%), 20-24 years population, from the State of São Paulo (84.8%) and interior (62.3%). For Y1, there was statistically significant difference for 'pardo' (22.6%) - it can be translated as brown - and black (6.6%) - there wasn't black in Y3 and Y6 - ethnic groups, public school provenience - both elementary school (42.5%) and high school (73.6%) -, lower maternal schooling (high school, p < 0.001) and lower family income (p < 0.001). Years 3 and 6 majority was composed of white academics (76.7% and 90.3%, respectively), coming from private schools (basic education and high school), with further maternal education (higher education/post-graduation) and bigger average income. The influence factors leading to choice for medical specialty modified (p < 0,001) among graduation years. Y1 students opted more frequently for 'surgery/orthopedics' (37.7%), 'medical clinic/neurology' (23.6%) and 'psychiatry' (11.3%). To Y3, the most desired specialties were 'medical clinic/neurology' (40%), 'surgery/orthopedics' (13.4%) and 'obstetrician-gynecologist' (13.3%). Amongst Y6 undergraduates, the most chosen specialties were 'medical clinic/neurology' (24.5%), 'obstetrician-gynecologist' (20.2%) and 'surgery/orthopedics' (17%). Y1 academics also revealed different aspirations regarding intended future workplace, with larger desire to practice only on SUS or on international programs. In this context, results indicate that Unicamp inclusion policy and its modifications over the years, particularly in 2016 entrance exams, have been effective in broadening access to medical education, such as greater socio demographic, economic and ethnic plurality coupled with variations in reasons for choice of medical career and specialty among graduation years analyzed.

Cervical Cancer Registered in Two Developed Regions from Brazil: Upper Limit of Reachable Results from Opportunistic Screening.

OBJECTIVE: The aim of this study was to assess the time trends and pattern of cervical cancer diagnosed in the period from 2001 to 2012 by means of an opportunistic screening program from two developed regions in Brazil. METHODS: An observational study analyzing 3,364 cancer records (n = 1,646 from Campinas and n = 1,718 from Curitiba region) available in hospital-based cancer registries was done. An additional 1,836 records of CIN3/AIS from the region of Campinas was analyzed. The statistical analysis assessed the pooled data and the data by region considering the year of diagnosis, age-group, cancer stage, and histologic type. The Cochran-Armitage trend test was applied and p-values < 0.05 were considered significant. RESULTS: The total annual cervical cancer registered from 2001 to 2012 showed a slight drop (273-244), with an age average of 49.5 y, 13 years over the average for CIN3/AIS (36.8 y). A total of 20.6% of the diagnoses (1.6% under 25 y) were done out of the official screening age-range. The biennial rate of diagnoses by age group for the region of Campinas showed an increase trend for the age groups under 25 y (p = 0.007) and 25 to 44 y (p = 0.003). Stage III was the most recorded for both regions, with an annual average of 43%, without any trend modification. There was an increasing trend for stage I diagnoses in the region of Campinas (p = 0.033). The proportion of glandular histologic types registered had an increased trend over time (p = 0.002), higher for the region of Campinas (21.1% versus 12.5% for the region of Curitiba). CONCLUSION: The number, pattern and trends of cervical cancer cases registered had mild and slow modifications and reflect the limited effectivity of the opportunistic screening program, even in developed places.

OBJETIVO: Avaliar as tendências temporais e padrão de diagnóstico de câncer de colo de útero (CCU) através de programa de rastreamento oportunístico em duas regiões brasileiras desenvolvidas, no período de 2001 a 2012. MéTODOS: Estudo observacional com 3.364 registros de câncer (n = 1.646 da região de Campinas e n = 1.718 da região de Curitiba) obtidos de sistemas de registro hospitalar de câncer. Para a região de Campinas foram analisados 1.836 registros adicionais de CIN3/AIS. A análise estatística avaliou os dados agrupados e por região considerando o ano de diagnóstico, grupo etário, estágio de câncer e tipo histológico, e utilizou o teste de tendência Cochran-Armitage com valor p < 0,05. RESULTADOS: O total anual de CCU registrado no período de 2001 a 2012 apresentou uma ligeira queda (273 para 244), com idade média de 49,5 anos, 13 a mais que a idade média (36,8 anos) para CIN3/AIS. O total de diagnósticos realizados fora da faixa etária oficial de rastreamento foi 20,6% (1,6% abaixo de 25 anos). Houve uma tendência de aumento de casos nas faixas etárias inferior a 25 anos (p = 0,007) e de 25 a 44 anos (p = 0,003) para a região de Campinas. Ambas as regiões apresentaram maior proporção diagnósticos de câncer em estágio III (43% em média), sem modificação de tendência. Houve tendência crescente para diagnóstico em estágio I na região de Campinas (p = 0,033) e da proporção de tipos histológicos glandulares em ambas regiões (p = 0,002), 21,1% para a região de Campinas e 12,5% para Curitiba. CONCLUSãO: O número, o padrão e as tendências dos casos registrados de câncer de colo de útero apresentaram modificações pequenas e lentas ao longo do tempo, reflexo da efetividade limitada do programa de rastreio oportunista, mesmo em locais desenvolvidos.

Cervical cancer registered in two developed regions from Brazil: upper limit of reachable results from opportunistic screening / Câncer de colo de útero registrado em duas regiões desenvolvidas do Brasil: limite superior de resultados alcançáveis a partir do rastreamento oportunístico

Abstract Objective The aim of this study was to assess the time trends and pattern of cervical cancer diagnosed in the period from 2001 to 2012 by means of an opportunistic screening program from two developed regions in Brazil. Methods An observational study analyzing 3,364 cancer records (n = 1,646 from Campinas and n = 1,718 from Curitiba region) available in hospital-based cancer registries was done. An additional 1,836 records of CIN3/AIS from the region of Campinas was analyzed. The statistical analysis assessed the pooled data and the data by region considering the year of diagnosis, age-group, cancer stage, and histologic type. The Cochran-Armitage trend test was applied and p-values < 0.05 were considered significant. Results The total annual cervical cancer registered from2001 to 2012 showed a slight drop (273-244), with an age average of 49.5 y, 13 years over the average for CIN3/AIS (36.8 y). A total of 20.6% of the diagnoses (1.6% under 25 y) were done out of the official screening age-range. The biennial rate of diagnoses by age group for the region of Campinas showed an increase trend for the age groups under 25 y (p = 0.007) and 25 to 44 y (p = 0.003). Stage III was the most recorded for both regions, with an annual average of 43%, without any trend modification. There was an increasing trend for stage I diagnoses in the region of Campinas (p = 0.033). The proportion of glandular histologic types registered had an increased trend over time (p = 0.002), higher for the region of Campinas (21.1% versus 12.5% for the region of Curitiba). Conclusion The number, pattern and trends of cervical cancer cases registered had mild and slow modifications and reflect the limited effectivity of the opportunistic screening program, even in developed places.

Resumo Objetivo Avaliar as tendências temporais e padrão de diagnóstico de câncer de colo de útero (CCU) através de programa de rastreamento oportunístico em duas regiões brasileiras desenvolvidas, no período de 2001 a 2012. Métodos Estudo observacional com 3.364 registros de câncer (n = 1.646 da região de Campinas e n = 1.718 da região de Curitiba) obtidos de sistemas de registro hospitalar de câncer. Para a região de Campinas foram analisados 1.836 registros adicionais de CIN3/AIS. A análise estatística avaliou os dados agrupados e por região considerando o ano de diagnóstico, grupo etário, estágio de câncer e tipo histológico, e utilizou o teste de tendência Cochran-Armitage com valor p < 0,05. Resultados O total anual de CCU registrado no período de 2001 a 2012 apresentou uma ligeira queda (273 para 244), comidade média de 49,5 anos, 13 amais que a idade média (36,8 anos) para CIN3/AIS. O total de diagnósticos realizados fora da faixa etária oficial de rastreamento foi 20,6% (1,6% abaixo de 25 anos). Houve uma tendência de aumento de casos nas faixas etárias inferior a 25 anos (p = 0,007) e de 25 a 44 anos (p = 0,003) para a região de Campinas. Ambas as regiões apresentaram maior proporção diagnósticos de câncer em estágio III (43% em média), sem modificação de tendência. Houve tendência crescente para diagnóstico em estágio I na região de Campinas (p = 0,033) e da proporção de tipos histológicos glandulares em ambas regiões (p = 0,002), 21,1% para a região de Campinas e 12,5% para Curitiba. Conclusão O número, o padrão e as tendências dos casos registrados de câncer de colo de útero apresentaram modificações pequenas e lentas ao longo do tempo, reflexo da efetividade limitada do programa de rastreio oportunista, mesmo em locais desenvolvidos.

Job satisfaction of nursing staff in a university hospital.

OBJECTIVE: identify the determinants of job satisfaction of the nursing staff of a public university hospital. METHOD: secondary study with mixed data approach and simple and multiple linear regression. A total of 115 subjects participated in the study, 41 nurses and 74 nursing assistants and technicians. The data collection occurred in 2013 using the QST-Caism questionnaire. RESULTS: education, hierarchical level and workplace constitute job satisfaction determinants. However, age, gender, job and work period did not show this relationship. More educated workers held low job satisfaction if exercised not graduated nursing functions. CONCLUSION: graduated workers who perform high school functions are more unsatisfied than those who have high school function and qualification.

Satisfação no trabalho no contexto hospitalar: uma análise segundo o gênero / Job satisfaction in a hospital context: an analysis according to gender / Satisfacción laboral en el contexto hospitalario: un análisis según el género

Objetivo: Avaliar a satisfação no trabalho em um hospital público universitário segundo o gênero dos(as) trabalhadores(as). Métodos: Realizou-se análise secundária com enfoque misto e amostra de 308 sujeitos, sendo 240 mulheres e 68 homens. Resultados: Quase metade das mulheres desempenhavam funções de enfermagem. A função mais comum entre os homens era a administrativa. O grupo masculino apresentou maior satisfação geral e nos três domínios avaliados. Na análise ajustada, só se observou significância estatística para o domínio "Condições de Trabalho", indicando que os aspectos físicos do trabalho geram as maiores assimetrias entre os gêneros, principalmente em relação a banheiros e nível de barulhos no ambiente. Conclusão: Uma vez que as demais diferenças entre os grupos não resultaram significativas na análise ajustada, conclui-se que os menores níveis de satisfação das mulheres tenham sido influenciados pela expressiva concentração feminina em funções da enfermagem, que constituíam o grupo profissional mais insatisfeito do estudo.

Objective: To assess job satisfaction in a public hospital according to workers' gender. Methods: It was conducted a secondaryanalysis with mixed method, from a sample of 308 subjects: 240 women and 68 men. Results: Almost half of women playedfunctions of nursing. The most common function among men was the administrative. Men showed greater overall satisfaction,as well as for the three domains assessed. In adjusted analyses, statistical significance was observed only for the "WorkingConditions" domain, indicating that the physical aspects of the job generate the larger asymmetries between the genders, especiallyin relation to toilets and level of noise in the environment. Conclusion: Since the other differences between the groups did notresult significant in the adjusted analysis, it is concluded that the lower levels of satisfaction of women have been influenced bytheir expressive concentration in nursing functions, the most dissatisfied professional group in this study.

Objetivo: Evaluar la satisfacción laboral en un hospital público universitario a partir del género de los(as) trabajadores(as).Métodos: Se realizó un análisis secundario con enfoque mixto. Participaron 308 sujetos, habiendo 240 mujeres y 68 hombres.Resultados: Casi mitad de las mujeres tenían trabajos de enfermería. La función más común entre el género masculino era laadministrativa. Los hombres mostraron mayor satisfacción general y en los tres dominios evaluados. En el análisis ajustado, seobservó solamente la significación estadística para el dominio "Condiciones de Trabajo", indicando que los aspectos físicosgeneran las mayores asimetrías entre los sexos, especialmente para los aseos y el nivel de ruido ambiente. Conclusión: Dadoque las otras diferencias entre géneros no resultaron significativas en el análisis ajustado, se concluye que los niveles inferioresde satisfacción femenina fueran influenciados por la concentración predominante en funciones de enfermería, grupo profesionalque ha demostrado mayor insatisfacción en el estudio.

Satisfação no trabalho da equipe de enfermagem em um hospital universitário / Satisfacción en el trabajo del personal de enfermería en un hospital universitario / Job satisfaction of nursing staff in a university hospital

RESUMO Objetivo: identificar os determinantes da satisfação no trabalho da equipe de enfermagem de um hospital público universitário. Método: estudo secundário, com abordagem mista dos dados e análise de regressão linear simples e múltipla. Participaram da pesquisa 115 sujeitos, sendo 41 enfermeiros e 74 técnicos e auxiliares de enfermagem. A coleta de dados ocorreu em 2013, mediante a aplicação do questionário QST-Caism. Resultados: escolaridade, cargo e local de trabalho constituem determinantes da satisfação. Já idade, sexo, função e período de trabalho não apresentaram essa relação. Trabalhadores mais escolarizados detinham baixa satisfação no trabalho se exercessem funções de técnico e de auxiliares de enfermagem. Conclusão: trabalhadores graduados desempenhando funções de ensino médio estão mais insatisfeitos do que aqueles com função e formação de ensino médio.

RESUMEN Objetivo: identificar los determinantes de la satisfacción laboral del personal de enfermería de un hospital público y universitario. Método: estudio secundario, con enfoque mixto y análisis de regresión lineal simple y múltiple. Participaron 115 sujetos, incluyendo 74 enfermeras y 41 técnicos y auxiliares de enfermería. La recolección ocurrió en 2013 por el QST-Caism. Resultados: nivel de educación, cargo y lugar de trabajo son determinantes de la satisfacción. Por su parte, período de trabajo, edad, sexo y función no muestran esta relación. Trabajadores más instruidos tenían baja satisfacción cuando sus funciones eran asistentes o técnicos de enfermería. Conclusión: trabajadores graduados desempeñando funciones de escuela secundaria son más insatisfechos que trabajadores con función y calificación de escuela secundaria.

ABSTRACT Objective: identify the determinants of job satisfaction of the nursing staff of a public university hospital. Method: secondary study with mixed data approach and simple and multiple linear regression. A total of 115 subjects participated in the study, 41 nurses and 74 nursing assistants and technicians. The data collection occurred in 2013 using the QST-Caism questionnaire. Results: education, hierarchical level and workplace constitute job satisfaction determinants. However, age, gender, job and work period did not show this relationship. More educated workers held low job satisfaction if exercised not graduated nursing functions. Conclusion: graduated workers who perform high school functions are more unsatisfied than those who have high school function and qualification.

High Prevalence of Infertility among Women with Graves' Disease and Hashimoto's Thyroiditis.

Objectives. To evaluate the prevalence of infertility in women with Graves' disease (GD) or Hashimoto's thyroiditis (HT) and associated factors. Material and Methods. This cross-sectional study was conducted at the Endocrinology Clinic for Thyroid Autoimmune Diseases, with 193 women aged 18-50 years with GD and 66 women aged 18-60 years with HT. The women were interviewed to obtain data on their gynecological and obstetric history and family history of autoimmune diseases. Their medical records were reviewed to determine the characteristics of the disease and to confirm association with other autoimmune diseases. Infertility was defined as 12 months of unprotected sexual intercourse without conception. Results. The prevalence of infertility was 52.3% in GD and 47.0% in HT. Mean age at diagnosis was 36.5 years and 39.2 years, in GD and HT, respectively. The mean number of pregnancies was lower in women who were 35 years old or younger at diagnosis and was always lower following diagnosis of the disease, irrespective of age. The only variable associated with infertility was a shorter time of the disease in HT. Conclusions. The prevalence of infertility was high in women with GD and HT and affected the number of pregnancies in young women.

IL10 inversely correlates with the percentage of CD8⁺ cells in MDS patients.

The role of the immune system in myelodysplastic syndrome (MDS) progression has been widely accepted, although mechanisms underlying this immune dysfunction are not clear. CD4(+) and CD8(+) lymphocyte profiles in the peripheral blood of MDS patients were evaluated and correlated with clinical characteristics, the expression of FOXP3 and the anti-inflammatory cytokines IL10, TGFß1 and CTLA4. IL10 expression inversely correlated with the percentage of CD8(+) cells and was higher in high-risk MDS. Our findings provide further evidence for the role of T cell-mediated IL10 production in MDS and strengthen the idea of distinct cytokine profiles in low and high-risk MDS.

Validação do Questionário de Satisfação no Trabalho em Hospital Universitário / Validation of a University Hospital Job Satisfaction Questionnaire

O trabalho ocupa grande parte do tempo de vida das pessoas e a satisfação obtida com ele tem sido considerada um importante aspecto da saúde física e mental. O objetivo deste trabalho foi descrever a validação do Questionário de Satisfação no Trabalho do Hospital da Mulher Professor Doutor José Aristodemo Pinotti - CAISM da Universidade Estadual de Campinas (QST-CAISM). Quatro amostras participaram da pesquisa: a primeira compôs o painel de especialistas; a segunda participou da etapa de pré-teste; a terceira, do teste e a quarta respondeu a versão final do questionário. Um total de 328 funcionários respondeu a versão final do QST-CAISM. Os dados foram submetidos a análise fatorial exploratória. A sensibilidade foi verificada comparando-se os índices de satisfação de funcionários com cargos de chefia e/ou gratificados com os demais funcionários. A consistência interna foi verificada por meio do coeficiente alfa de Cronbach e da técnica de metades partidas. Identificaram-se três fatores com níveis satisfatórios de consistência interna geral, além de uma correlação satisfatória entre as metades partidas. O questionário foi sensível para discriminar significativamente os grupos. Esses resultados sustentam que o questionário possui propriedades psicométricas satisfatórias, corroborando a intenção de aferir a satisfação no trabalho dos colaboradores do CAISM

Work fills a large part of life and, as such, job satisfaction has been considered an important aspect of mentaland physical health. The purpose of this study was to describe the validation of the Hospital da Mulher Professor Doutor José Aristodemo Pinotti-CAISM of the Universidade Estadual de Campinas (QST-CAISM) Job Satisfaction Questionnaire. This research was composed of four samples: the first assembled the specialist panel; the second took part on the pre-test stage; the third participated on the test and the fourth answered the final version of the questionnaire. A total of 328 workers answered the final version of the questionnaire. The data were submittedto exploratory factor analysis, with the sensitivity being verified by comparing the satisfaction indexes of employees in management positions and/or those receiving bonuses with the rest of the employees. The internal consistency was verified through the Cronbach’s alpha coefficient and the split half technique. Three factors were identified with satisfactory levels of internal consistency, besides a satisfactory correlation of the split halves. The questionnaire was sensitive enough to differentiate significantly the groups. These results indicate that the questionnaire has satisfactory psychometric properties, confirming the intent of measuring the job satisfaction levels of CAISM employees

Validade de medidas antropométricas autorreferidas em adolescentes: sua relação com percepção e satisfação corporal / Anthropometric self-reported measures: relationship to body image perception and satisfaction among adolescents

OBJETIVO: Verificar a validade da classificação do estado nutricional e da estatura para idade quando utilizadas massa corporal e estatura autorreferidas por adolescentes, bem como relacionar essa validade com percepção e com satisfação corporal. MÉTODOS: 304 adolescentes antes de terem suas medidas de massa e estatura aferidas autorreferiram essas medidas, foram questionados sobre a percepção de seu corpo e a classificação da imagem corporal foi obtida com o uso de uma escala de silhuetas corporais. Também foram aplicados testes específicos para avaliar a satisfação corporal e o comportamento alimentar. RESULTADOS: As classificações feitas com base nos dados autorreferidos e aferidos tiveram concordância alta (K = 1,00) para a classificação da estatura por idade e moderada (K < 0,75) para a classificação de índice de massa corporal. No entanto, adolescentes que se consideravam "abaixo do peso" subestimaram o índice de massa corporal autorrelatado e, os que se percebiam como "gordos", o superestimaram. As meninas e os que se classificaram como obesos tenderam a subestimar o índice de massa corporal, e os meninos, a superestimá-lo. CONCLUSÃO: Os adolescentes autorrelataram suas medidas de massa e estatura de maneira adequada. No entanto, o sexo, a percepção e a classificação da imagem corporal foram variáveis que influenciaram na obtenção de respostas não válidas.

OBJECTIVE: To assess the reliability of the classification for nutritional status and height-for-age when using self-reported weight and height and its relationships with self-reported data of body image perception and satisfaction among adolescents. METHODS: In this retrospective study, 304 adolescents before they had measured their height and weight, they self-reported these measures, they were asked about their body shape perception and body image classification was obtained by using a body silhouette scale. It was also used specific tests to assess body satisfaction and food behavior. RESULTS: It was found full agreement between height-for-age classification using self-reported and measured height (k = 1.00) and an intermediate level of agreement between body mass index calculated with self-reported and measured data (k < 0.75). However, adolescents who perceived themselves as "skinny" underestimated their self-reported body mass index whereas those who perceived themselves as "fat" overestimated it. Those who perceived themselves as fat in the silhouette scale underestimated their body mass index. Gender was also a factor for unreliable answers, as females tended to underestimate their self-reported body mass index and males to overestimate it. CONCLUSION: The adolescents adequately self-reported weight and height information. However, body shape perception and body image classification were factors affecting answer reliability.

Body mass index percentiles in adolescents of the city of São Paulo, Brazil, and their comparison with international parameters.

OBJECTIVE: To describe the percentile distribution of body mass index (BMI) in school adolescents, by gender and age, comparing them with international parameters. SUBJECTS AND METHODS: The study included 8,020 adolescents aged 10-15 years from 43 schools in the city of São Paulo, southeastern Brazil. BMI values of the study sample were distributed in percentiles and compared to international parameters (CDC, Must and cols. and Cole and cols.). RESULTS: Both male and female adolescents aged 10 to 14 years showed BMI cut-offs over the international parameters, especially in the P50-P85 percentile range. At the age of 15, the observed values were very similar to reference data; however, BMI values in the 95th percentile were much higher than international parameters. CONCLUSIONS: The study results show how important it is to use adequate BMI values for Brazilian adolescents aged 10-15 since international parameters may not reflect the actual nutritional status of this group.

Incidência e fatores de risco para a extubação acidental em uma unidade de terapia intensiva neonatal / Incidence and risk factors of accidental extubation in a neonatal intensive care unit

OBJETIVO: Determinar a incidência e fatores de risco para a extubação acidental (EA) em uma unidade de terapia intensiva neonatal de nível terciário. MÉTODOS: Estudo de coorte prospectivo para determinar a densidade de incidência de EA por 100 pacientes-dia, no período de 23 meses, em 222 recém-nascidos em assistência ventilatória (AV). Foram estudados os fatores de risco para a EA utilizando análise de regressão logística. A presença de padrão cíclico nas taxas de extubação, segundo variáveis de interesse, foi investigada pela análise de Cosinor. RESULTADOS: A média da taxa de EA foi de 5,34/100 pacientes-dia ventilados. As variáveis preditoras que se associaram à EA foram o uso subsequente da via oral e nasal durante a AV [risco relativo (RR) = 4,73; intervalo de confiança de 95 por cento (IC95 por cento) 1,92-11,60], a duração da AV (a cada dia RR = 1,03; IC95 por cento 1,02-1,04) e o número de pacientes-dia ventilados (RR = 1,01; IC95 por cento 1,01-1,02). Pela regressão múltipla ajustada, o tempo total de AV foi o único preditor independente para a EA nesta amostra (RR = 1,02; IC95 por cento 1,01-1,03). O tempo de AV de 10,5 dias apresentou acurácia de 0,79 (IC95 por cento 0,71-0,87) para a ocorrência de EA. A análise de Cosinor demonstrou periodicidade significativa na taxa geral de EA e no número de pacientes-dia ventilados. Houve correlação significativa entre o número de pacientes-dia e a frequência de EA. CONCLUSÃO: A densidade média de EA foi de 5,34/100 pacientes-dia. O único preditor independente para EA foi a duração da AV. A melhor acurácia para a ocorrência de EA foi obtida aos 10,5 dias de duração da AV.

OBJECTIVE: To determine the incidence and risk factors of accidental extubation (AE) in a tertiary neonatal intensive care unit. METHODS: A prospective cohort study was conducted to determine AE incidence density per 100 patient-days, during a 23-month period, in 222 newborns receiving assisted ventilation (AV). Logistic regression analysis was used to determine risk factors for AE. The presence of a cyclical pattern in extubation rates, according to the variables of interest, was investigated by Cosinor analysis. RESULTS: The mean AE rate was 5.34/100 patient-days ventilated. AE-associated predictive variables were: subsequent use of the oral and nasal routes during AV [relative risk (RR) = 4.73; 95 percent confidence interval (95 percentCI) 1.92-11.60], AV duration (per day, RR = 1.03; 95 percentCI 1.02-1.04), and number of patient-days ventilated (RR = 1.01; 95 percentCI 1.01-1.02). According to the adjusted multiple regression analysis, total AV time was the only independent predictor of AE in this sample (RR = 1.02; 95 percentCI 1.01-1.03). AV time of 10.5 days showed an accuracy of 0.79 (95 percentCI 0.71-0.87) for the occurrence of AE. Cosinor analysis showed significant periodicity in overall AE rate and in the number of patient-days ventilated. There was a significant correlation between the number of patient-days ventilated and AE frequency. CONCLUSION: Mean AE density was 5.34/100 patient-days ventilated. AV duration was the only independent predictor of AE. The best accuracy for AE occurrence was achieved at 10.5 days of AV duration.

Incidence and risk factors of accidental extubation in a neonatal intensive care unit.

OBJECTIVE: To determine the incidence and risk factors of accidental extubation (AE) in a tertiary neonatal intensive care unit. METHODS: A prospective cohort study was conducted to determine AE incidence density per 100 patient-days, during a 23-month period, in 222 newborns receiving assisted ventilation (AV). Logistic regression analysis was used to determine risk factors for AE. The presence of a cyclical pattern in extubation rates, according to the variables of interest, was investigated by Cosinor analysis. RESULTS: The mean AE rate was 5.34/100 patient-days ventilated. AE-associated predictive variables were: subsequent use of the oral and nasal routes during AV [relative risk (RR) = 4.73; 95% confidence interval (95%CI) 1.92-11.60], AV duration (per day, RR = 1.03; 95%CI 1.02-1.04), and number of patient-days ventilated (RR = 1.01; 95%CI 1.01-1.02). According to the adjusted multiple regression analysis, total AV time was the only independent predictor of AE in this sample (RR = 1.02; 95%CI 1.01-1.03). AV time of 10.5 days showed an accuracy of 0.79 (95%CI 0.71-0.87) for the occurrence of AE. Cosinor analysis showed significant periodicity in overall AE rate and in the number of patient-days ventilated. There was a significant correlation between the number of patient-days ventilated and AE frequency. CONCLUSION: Mean AE density was 5.34/100 patient-days ventilated. AV duration was the only independent predictor of AE. The best accuracy for AE occurrence was achieved at 10.5 days of AV duration.

Body mass index percentiles in adolescents of the city of São Paulo, Brazil, and their comparison with international parameters / Percentis do índice de massa corporal de adolescentes na cidade de São Paulo, Brasil, e sua comparação com parâmetros internacionais

OBJECTIVE: To describe the percentile distribution of body mass index (BMI) in school adolescents, by gender and age, comparing them with international parameters. SUBJECTS AND METHODS: The study included 8,020 adolescents aged 10-15 years from 43 schools in the city of São Paulo, southeastern Brazil. BMI values of the study sample were distributed in percentiles and compared to international parameters (CDC, Must and cols. and Cole and cols.). RESULTS: Both male and female adolescents aged 10 to 14 years showed BMI cut-offs over the international parameters, especially in the P50-P85 percentile range. At the age of 15, the observed values were very similar to reference data; however, BMI values in the 95th percentile were much higher than international parameters. CONCLUSIONS: The study results show how important it is to use adequate BMI values for Brazilian adolescents aged 10-15 since international parameters may not reflect the actual nutritional status of this group.

OBJETIVO: Distribuição do índice de massa corporal (IMC) em percentis dos adolescentes escolares, divididos por sexo e idade, comparando-os com os parâmetros internacionais. SUJEITOS E MÉTODOS: Participaram do estudo 8.020 adolescentes de 10 a 15 anos de 43 escolas da cidade de São Paulo. Os valores do IMC dessa população foram distribuídos em percentis e comparados com os parâmetros internacionais (CDC, Must e Cole). RESULTADOS: Os adolescentes dos 10 aos 14 anos de idade, do sexo masculino e feminino, apresentaram pontos de corte do IMC acima dos internacionais, especialmente no intervalo P50-85. Aos 15 anos de idade, os valores observados foram muito semelhantes, no entanto, o IMC no valor do percentil 95 foi muito mais elevado do que os parâmetros internacionais. CONCLUSÕES: Os resultados deste estudo demonstram a importância de utilizar valores adequados para adolescentes brasileiros de 10 a 15 anos, uma vez que os parâmetros internacionais podem não refletir a real condição do estado nutricional dessa população.

Prevalência de sintomas auditivos e vestibulares em trabalhadores expostos a ruído ocupacional / Prevalencia de síntomas auditivos y vestibulares en trabajadores expuestos al ruido ocupacional / Prevalence of auditory and vestibular symptoms among workers exposed to occupational noise

O objetivo do estudo foi estimar a prevalência de sintomas auditivos e vestibulares em trabalhadores expostos a ruído ocupacional. Foram analisados os prontuários de 175 trabalhadores com perda auditiva induzida por ruído, atendidos em um centro de referência de saúde ocupacional de Campinas, SP, de 1997 a 2003. As variáveis estudadas foram freqüência dos sintomas de hipoacusia, zumbido e vertigem. As associações com idade, tempo de exposição ao ruído e limiares auditivos tonais foram analisadas utilizando-se os testes estatísticos qui-quadrado e exato de Fisher. Foram relatados hipoacusia em 74 por cento dos casos, zumbidos em 81 por cento e vertigem em 13,2 por cento. Verificou-se associação entre hipoacusia e idade, tempo de exposição ao ruído e limiares auditivos tonais e entre vertigem e tempo de exposição ao ruído, não sendo encontradas outras associações significativas.

The purpose of the study was to assess the prevalence of auditory and vestibular symptoms in workers exposed to occupational noise. There were examined medical records of 175 workers with noise-induced hearing loss who attended an occupational health reference center in the city Campinas, Southeastern Brazil, from 1997 to 2003. The variables studied were frequency of symptoms of hypoacusis, tinnitus, and vertigo. Association with age, noise exposure time, and auditory thresholds were analyzed using the chi-square test and Fisher's exact test. Hypoacusis was reported in 74 percent of cases, tinnitus in 81 percent, and vertigo in 13.2 percent. There was found an association between hypoacusis and age, noise exposure time, and auditory thresholds and between vertigo and noise exposure time. No other significant associations were found.

El objetivo del estudio fue estimar la prevalencia de síntomas auditivos y vestibulares en trabajadores expuestos al ruido ocupacional. Fueron analizados los prontuarios de 175 trabajadores con pérdida auditiva inducida por ruido, atendidos en un centro de referencia de salud ocupacional de Campinas, Sureste de Brasil, de 1997 a 2003. Las variables estudiadas fueron frecuencia de los síntomas de hipoacusia, zumbido y vértigo. Las asociaciones con edad, tiempo de exposición al rudio y límites auditivos tonales fueron analizados utilizándose las pruebas estadísticas chi-cuadrado y exacto de Fisher. Fueron relatados hipoacusia en 74 por ciento de los casos, zumbidos en 81 por ciento y vértigo en 13,2 por ciento. Se verificó asociación entre hipoacusia y edad, tiempo de exposición al ruido y límites auditivos tonales y entre vértigo y tiempo de exposición al ruido, no siendo encontradas otras asociaciones significativas.

[Prevalence of auditory and vestibular symptoms among workers exposed to occupational noise]. / Prevalência de sintomas auditivos e vestibulares em trabalhadores expostos a ruído ocupacional.

The purpose of the study was to assess the prevalence of auditory and vestibular symptoms in workers exposed to occupational noise. There were examined medical records of 175 workers with noise-induced hearing loss who attended an occupational health reference center in the city Campinas, Southeastern Brazil, from 1997 to 2003. The variables studied were frequency of symptoms of hypoacusis, tinnitus, and vertigo. Association with age, noise exposure time, and auditory thresholds were analyzed using the chi-square test and Fisher's exact test. Hypoacusis was reported in 74% of cases, tinnitus in 81%, and vertigo in 13.2%. There was found an association between hypoacusis and age, noise exposure time, and auditory thresholds and between vertigo and noise exposure time. No other significant associations were found.