ABSTRACT
PURPOSE OF INVESTIGATION: To determine the prevalence of endometriosis in patients with epithelial ovarian cancer and explore the differences between women with endometrioid and clear-cell histologic subtypes with and without associated endometriosis. MATERIALS AND METHODS: The medical charts of 496 patients with epithelial ovarian cancer at the Hospital Virgin de la Arrixaca (Murcia, Spain) between 1971 and 2010 were reviewed. RESULTS: Endometriosis was present in 27 (5.4%) of the 496 cases (p < 0001), and was associated with the endometrioid histotype in 13/45 cases (29%) and with the clear cell histotype in 7/22 (32%). The prevalence of an association with endometriosis according to histologic type was 28.8% (13/45) for endometrioid carcinoma and 31.8% (7/22) for clear-cell carcinoma. CONCLUSION: Both endometrioid and clear-cell ovarians tumours are associated with pelvic endometriosis. Patients with endometiosis associated ovarian cancer differ from non-endometiosis associated ovarian cancer in their clinical characteristics.
Subject(s)
Adenocarcinoma, Clear Cell/epidemiology , Carcinoma, Endometrioid/epidemiology , Endometriosis/epidemiology , Ovarian Neoplasms/epidemiology , Ovarian Neoplasms/pathology , Adenocarcinoma, Clear Cell/pathology , Adult , Aged , Carcinoma, Endometrioid/pathology , Female , Humans , Middle Aged , Prevalence , Retrospective Studies , Spain/epidemiologyABSTRACT
⺠This is the second report of pregnancy following endometrial stromal sarcoma (ESS). ⺠The role of adnexectomy is controversial in stage I ESS. ⺠Adnexectomy does not appear to affect survival in stage I ESS.
ABSTRACT
Propósito: Describir un estudio anatomoclínico de un tipo infrecuente de carcinoma adenoescamoso pobremente diferenciado de cérvix, incidiendo en el perfil inmunohistoquímico de éste. Material y métodos: Se trata de una mujer de 59 años que presenta una tumoración polipoide en cérvix, que se extirpa, procediendo a su estudio anatomopatológico, que aporta el diagnóstico de carcinoma de células de citoplasma esmerilado. Se realiza tratamiento quirúrgico con histerectomía y doble anaexectomía. La paciente está libre de evidencia de enfermedad a los 6 meses del diagnóstico. Resultados: Tumoración de estirpe epitelial (E.M.A., AE1-AE3, Cam 5.2 y C.E.A positivas) que se dispone en nidos y cordones sólidos separados por estroma fibrovascular con abundante infiltrado linfoide. Los nidos tumorales muestran celularidad con notable atipia y característico aspecto esmerilado de citoplasma. Conclusiones: Se realiza una aportación al estudio de las características inmunohistoquímicas de esta infrecuente neoplasia (AU)
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