ABSTRACT
A case of the mixed disease of the connective tissue (MCTD) in male patient occupationally exposed to PVC and other toxic agents is presented. Clinical symptoms consisted of the typical signs of SLE, rheumatoid arthritis and lupoid hepatitis. MCTD diagnosis was confirmed serologically by the presence of autoantibodies anti-RNP. Prednisone administered in the daily dose of 60 mg produced remission.
Subject(s)
Chemical Industry , Mixed Connective Tissue Disease/chemically induced , Occupational Exposure , Polyvinyl Chloride/adverse effects , Adult , Hazardous Substances/adverse effects , Humans , Male , Mixed Connective Tissue Disease/diagnosis , Serologic TestsABSTRACT
Gasometric parameters were performed before, during and after bronchoalveolar lavage (BAL) in 21 patients with mild bronchial asthma. In addition, spirometric parameters were performed before and after BAL. Decrease of pO2, SaO2 and increase of pCO2 which kept within the limits of normal values were observed. After BAL gasometric parameters returned to baseline values. Bronchoalveolar lavage caused statistically significant fall in FEV1 and PEF. BAL was well tolerated and did not worse the clinical state of patients.