ABSTRACT
The alcoholic extract of the fresh bulbs of Cyrtanthus elatus yielded zephyranthine (1) and 1,2-O-diacetylzephyranthine (2), together with three other known alkaloids. Complete assignment of 1H and 13C NMR spectra of compounds 1 and 2 was done by employment of two-dimensional NMR techniques.
Subject(s)
Alkaloids/pharmacology , Eukaryota/drug effects , Magnoliopsida , Phenanthridines , Plants, Medicinal , Alkaloids/chemistry , Alkaloids/isolation & purification , Animals , Entamoeba/drug effects , Humans , Magnetic Resonance Spectroscopy , Parasitic Sensitivity Tests , Plant Extracts/chemistry , Plant Extracts/pharmacology , Plasmodium falciparum/drug effects , Trypanosoma/drug effectsABSTRACT
Eight alkaloids have been isolated from Zephyranthes citrina (Amaryllidaceae). The alkaloid oxomaritidine is reported here for the first time from a natural source. The structure and stereochemistry of the alkaloids were determined by physical and spectroscopic methods.
Subject(s)
Alkaloids/isolation & purification , Amaryllidaceae Alkaloids , Cyclopropanes/isolation & purification , Plants, Medicinal/chemistry , Alkaloids/chemistry , Cyclopropanes/chemistry , Magnetic Resonance Spectroscopy , Molecular Structure , Spectrum AnalysisABSTRACT
Eleven alkaloids have been isolated from fresh bulbs of Crinum macowanii (Amaryllidaceae). Macowine is reported here for the first time. The structure and stereochemistry of this new alkaloid as well as of the known ones were determined by physical and spectroscopic methods.
