ABSTRACT
Paciente de 40 años de edad, sin alergias medicamentosas conocidas y sin antecedentesde interés, que es traído a Urgencias por dispositivo de cuidados críticos por politraumatismo tras accidente de moto...
Paciente de 40 años de edad, sin alergias medicamentosas conocidas y sin antecedentesde interés, que es traído a Urgencias por dispositivo de cuidados críticos por politraumatismo tras accidente de moto...
Subject(s)
Kidney Diseases , Constriction, Pathologic , HumansABSTRACT
No disponible
Subject(s)
Humans , Adult , Constriction, Pathologic/diagnosis , Ureteral Obstruction/diagnosis , Kidney/injuries , Spleen/injuries , Nephrectomy , Kidney Pelvis/injuries , Accidents, Traffic , Incidental FindingsABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Wounds and Injuries/diagnosis , Wounds and Injuries/pathology , Wounds and Injuries/therapy , Kidney/injuries , Kidney/physiology , Kidney/surgery , Abdominal Pain/chemically induced , Urinoma/therapy , Catheters , Tomography, X-Ray Computed/instrumentation , Tomography, X-Ray Computed/methods , Tomography, X-Ray Computed , Fluid Therapy/instrumentation , Fluid Therapy/methods , Fluid TherapyABSTRACT
OBJECTIVE: To generate and to evaluate ex vivo a novel model of bioengineered human bladder mucosa based on fibrin-agarose biomaterials. METHODS: We first established primary cultures of stromal and epithelial cells from small biopsies of the human bladder using enzymatic digestion and selective cell culture media. Then, a bioengineered substitute of the bladder lamina propria was generated using cultured stromal cells and fibrin-agarose scaffolds, and the epithelial cells were then subcultured on top to generate a complete bladder mucosa substitute. Evaluation of this substitute was carried out by cell viability and histological analyses, immunohistochemistry for key epithelial markers and transmission electron microscopy. RESULTS: The results show a well-configured stroma substitute with a single-layer epithelium on top. This substitute was equivalent to the control bladder mucosa. After 7 days of ex vivo development, the epithelial layer expressed pancytokeratin, and cytokeratins CK7, CK8 and CK13, as well as filaggrin and ZO-2, with negative expression of CK4 and uroplakin III. A reduction of the expression of CK8, filaggrin and ZO-2 was found at day 14 of development. An immature basement membrane was detected at the transition between the epithelium and the lamina propria, with the presence of epithelial hemidesmosomes, interdigitations and immature desmosomes. CONCLUSIONS: The present results suggest that this model of bioengineered human bladder mucosa shared structural and functional similarities with the native bladder mucosa, although the epithelial cells were not fully differentiated ex vivo. We hypothesize that this bladder mucosa substitute could have potential clinical usefulness after in vivo implantation.
Subject(s)
Mucous Membrane/cytology , Tissue Engineering/methods , Urinary Bladder/cytology , Adult , Aged , Basement Membrane/ultrastructure , Biocompatible Materials , Cell Survival , Epithelial Cells , Fibrin , Filaggrin Proteins , Humans , Intermediate Filament Proteins/analysis , Keratin-13/analysis , Keratin-4/analysis , Keratin-7/analysis , Keratin-8/analysis , Male , Middle Aged , Mucous Membrane/chemistry , Mucous Membrane/ultrastructure , Primary Cell Culture , Sepharose , Stromal Cells , Tissue Scaffolds , Uroplakin III/analysis , Zonula Occludens-2 Protein/analysisABSTRACT
A 33 year-old male, who five years earlier was operated for a nodular melanoma in vertical growth phase of 1.5mm thick (Breslow), Clark II-III, presented to the Emergency department with a progressive increase of the left testicle. Ultrasound scan examination revealed a 2 x 2 cm solid mass in the left testis, with normal right testis.With the diagnosis of testicular neoplasm, we requested Alpha-fetoprotein and beta HCG levels, and patient underwent radical orchiectomy.
Subject(s)
Melanoma/secondary , Testicular Neoplasms/secondary , Adult , Fatal Outcome , Humans , Male , Melanoma/pathology , Testicular Neoplasms/pathologyABSTRACT
OBJECTIVE: Testicular epidermoid cyst is a rare clinical entity that accounts for 1% of testicular neoplasias. METHODS AND RESULTS: We report two cases of testicular epidermoid cysts in a 18 and 19 year old males with a painless testicular lesion. Testicular US was carried out showing a hypoechoic nodule in both cases. With the suspicion of testicular neoplasm inguinal orchiectomy was carried out with placement of testicular prostheses in the same act. The pathology report was testicular epidermoid cyst in both cases. CONCLUSIONS: Testicular epidermoid cysts are an uncommon benign entity. When there is a suspicion of this diagnosis, based on tumor markers and ultrasound or MRI images, testicular parenchyma-sparing surgery must be attempted.
Subject(s)
Epidermal Cyst , Testicular Diseases , Adolescent , Epidermal Cyst/diagnostic imaging , Humans , Male , Testicular Diseases/diagnostic imaging , Ultrasonography , Young AdultABSTRACT
No disponible
Subject(s)
Adult , Humans , Male , Neoplasm Metastasis/pathology , Testicular Neoplasms/drug therapy , Testicular Neoplasms/radiotherapy , Melanoma/pathology , Diagnostic Imaging/methods , Orchiectomy/instrumentation , Orchiectomy/methods , Neoplasm Metastasis , Neoplasm Metastasis/diagnosis , Testicular Neoplasms/metabolism , Testicular Neoplasms/pathology , Melanoma/mortality , Diagnostic Imaging , Testis/pathology , Testis , Immunohistochemistry/instrumentation , ImmunohistochemistryABSTRACT
OBJECTIVE: To report a case of GIST type retroperitoneal tumor with spontaneous rupture to the abdominal cavity causing acute abdomen secondary to hemoperitoneum. METHODS/RESULTS: We report the case of an 84 year-old man with history of BPH and chronic atrial fibrillation. He presented to the Emergency Department with diffuse abdominal pain, syncope and accompanying vegetative symptoms. Diagnostic work up showed a 19 cm retroperitoneal mass dependent of the left kidney with active bleeding and secondary hemoperitoneum. Left radical nephrectomy was performed with pathology report of gastrointestinal stromal tumor attached to the renal capsule. CONCLUSIONS: Spontaneous hemoperitoneum is a rare entity and it has various etiologies. It is rarely described in retroperitoneal tumors.
Subject(s)
Gastrointestinal Stromal Tumors/complications , Hemoperitoneum/etiology , Kidney Neoplasms/complications , Retroperitoneal Neoplasms/complications , Aged, 80 and over , Gastrointestinal Stromal Tumors/diagnostic imaging , Gastrointestinal Stromal Tumors/surgery , Hemoperitoneum/therapy , Humans , Kidney Neoplasms/diagnostic imaging , Kidney Neoplasms/surgery , Male , Radiography , Retroperitoneal Neoplasms/diagnostic imaging , Retroperitoneal Neoplasms/surgery , Rupture, SpontaneousSubject(s)
Aortic Aneurysm, Thoracic/diagnostic imaging , Hematoma/diagnostic imaging , Kidney Diseases/diagnostic imaging , Thrombosis/diagnostic imaging , Aged , Anticoagulants/therapeutic use , Aorta, Thoracic/diagnostic imaging , Cysts/diagnostic imaging , Humans , Kidney Diseases/drug therapy , Male , Thrombosis/drug therapy , Tomography, X-Ray ComputedABSTRACT
OBJETIVO: Describimos un caso de tumor retroperitoneal tipo GIST con rotura espontánea a cavidad abdominal, ocasionando un cuadro de abdomen agudo secundario a hemoperitoneo. MÉTODO Y RESULTADOS: Varón de 84 años que acude a servicio de Urgencias de nuestro hospital por cuadro sincopal, con dolor abdominal difuso y cortejo vegetativo acompañante. Tras la realización de diferentes pruebas complementarias se objetiva una masa retroperitoneal de pendiente de riñón izquierdo de unos 19 cm con sangrado activo y hemoperitoneo secundario, por lo que se realiza una nefrectomía radical izquierda con resultado anatomopatológico de tumor estromal gastrointestinal dependiente de la capsula renal. CONCLUSIONES: El hemoperitoneo espontáneo es una entidad poco frecuente y de una etiología variada estando descrita en muy raras ocasiones en tumores retroperitoneales
OBJECTIVE: To report a case of GIST type retroperitoneal tumor with spontaneous rupture to the abdominal cavity causing acute abdomen secondary to hemoperitoneum. METHODS/RESULTS: We report the case of an 84 year-old man with history of BPH and chronic atrial fibrillation. He presented to the Emergency Department with diffuse abdominal pain, syncope and accompanying vegetative symptoms. Diagnostic work up showed a 19 cm retroperitoneal mass dependent of the left kidney with active bleeding and secondary hemoperitoneum. Left radical nephrectomy was performed with pathology report of gastrointestinal stromal tumor attached to the renal capsule. CONCLUSIONS: Spontaneous hemoperitoneum is a rare entity and it has various etiologies. It is rarely described in retroperitoneal tumors
Subject(s)
Humans , Hemoperitoneum/etiology , Retroperitoneal Neoplasms/complications , Rupture, Spontaneous/complications , Risk FactorsABSTRACT
No disponible
Subject(s)
Humans , Hematoma/etiology , Aortic Aneurysm, Thoracic/complications , Aortic Aneurysm, Abdominal/complications , Bowman Capsule/physiopathology , Drug-Eluting Stents , Endovascular ProceduresABSTRACT
OBJECTIVE: To describe one case of hematocele secondary to rupture of an abdominoscrotal hydrocele in an adult patient. METHODS AND RESULTS: We report a huge hematocele in a patient with this unusual type of hydrocele that suffered a minimal scrotal trauma. It was a hydrocele that extended through the inguinal canal to the retroperitoneal space. CONCLUSIONS: Abdominoscrotal hydrocele is a rare condition in children and even rarer in adults. The presence of a hematocele requires early surgical treatment.
Subject(s)
Hematocele/etiology , Hematocele/pathology , Testicular Hydrocele/complications , Testicular Hydrocele/pathology , Edema/pathology , Hematocele/surgery , Humans , Male , Rupture , Scrotum/pathology , Scrotum/surgery , Testicular Hydrocele/surgery , Urologic Surgical Procedures , Young AdultABSTRACT
OBJETIVO: Presentación de un caso de hematocele secundario a un hidrocele abdomino escrotal en la edad adulta. MÉTODO Y RESULTADO: Presentamos el caso de un paciente que presentó este inusual tipo de hidrocele que tras un mínimo traumatismo escrotal ocasionó un importante hematocele. Se trata de un hidrocele que se extiende a través del canal inguinal hacia el espacio retroperitoneal, reseñando su aproximación diagnóstica así como el tratamiento quirúrgico. CONCLUSIONES: El hidrocele abdomino escrotal es una patología infrecuente en niños y lo es aún más en adultos. La presencia de un hematocele exige un tratamiento quirúrgico precoz (AU)
OBJECTIVE: To describe one case of hematocele secondary to rupture of an abdominoscrotal hydrocele in an adult patient. METHODS AND RESULTS: We report a huge hematocele in a patient with this unusual type of hydrocele that suffered a minimal scrotal trauma. It was a hydrocele that extended through the inguinal canal to the retroperitoneal space. CONCLUSIONS: Abdominoscrotal hydrocele is a rare condition in children and even rarer in adults. The presence of a hematocele requires early surgical treatment (AU)
Subject(s)
Humans , Male , Testicular Hydrocele/complications , Abdominal Neoplasms/diagnosis , Hematocele/etiology , Testis/injuriesSubject(s)
Foreign Bodies/diagnostic imaging , Foreign Bodies/surgery , Urethra/diagnostic imaging , Urethral Diseases/diagnostic imaging , Urethral Diseases/surgery , Urinary Catheters/adverse effects , Humans , Male , Middle Aged , Radiography , Urinary Catheterization/adverse effects , Urinary Retention/diagnostic imaging , Urinary Retention/etiology , Urologic Surgical Procedures, MaleABSTRACT
No disponible
Subject(s)
Humans , Foreign-Body Reaction , Foreign Bodies/epidemiology , Foreign Bodies , Ureteral Diseases/complications , Ureteral DiseasesABSTRACT
We report a case of a rare congenital malformation, a urogenital sinus cyst in a young patient with non-specific symptoms for several months. A 21-year-old male presented with vague and intermittent abdominal pain. Ultrasound scan showed a retrovesical hypoechoic collection (approximately 6 cm) and left renal agenesis, compatible with a possible congenital malformation. These findings were confirmed by MRI. A laparoscopic excision of the cyst was performed with no complications. Pathology report confirmed a urogenital sinus cyst. The postoperative recovery was uneventful and the patient was discharged within 48 h. Urogenital sinus cysts are rare entities with few cases described in the literature. Imaging techniques such as ultrasound, CT or MRI may help with diagnosis. Therapeutic modalities range from observation to needle aspiration or surgical removal. In our case, we chose a laparoscopic approach to minimize morbidity and achieve an early recovery.
Subject(s)
Congenital Abnormalities/diagnostic imaging , Cysts/diagnostic imaging , Kidney Diseases/congenital , Seminal Vesicles/abnormalities , Congenital Abnormalities/surgery , Cysts/surgery , Humans , Kidney/abnormalities , Kidney/diagnostic imaging , Kidney/surgery , Kidney Diseases/diagnostic imaging , Kidney Diseases/surgery , Male , Seminal Vesicles/diagnostic imaging , Seminal Vesicles/surgery , Ultrasonography , Young AdultABSTRACT
OBJETIVOS: Presentar un caso de mielolipoma suprarrenal en un paciente de 53 años que debutó con una hemorragia retroperitoneal espontánea. MÉTODOS: La TAC mostró una masa de 14 cm en el área suprarrenal derecha de contenido graso, rodeada por otra hiperdensa sugestiva de hemorragia. Se realizó suprarrenalectomía derecha. Se revisa la literatura. RESULTADOS: El estudio histopatológico de la pieza confirmó el diagnóstico clínico de mielolipoma suprarrenal roto. CONCLUSIONES: Los mielolipomas suprarrenales son tumores poco frecuentes que generalmente no causan síntomas. La rotura espontánea de estos tumores es extremadamente rara, estando relacionada con el tamaño de los mismos. Sólo han sido descritos seis casos hasta ahora (AU)
