Subject(s)
Physical Therapy Modalities , Scoliosis/therapy , Traction/methods , Adolescent , Female , HumansABSTRACT
Five girls with idiopathic true precocious puberty are reported who underwent spontaneous regression of sexual development. In all patients the signs of sexual maturation were of moderate degree. Considering the possible spontaneous regression of precocious puberty, in similar cases it seems advisable to defer suppressive central therapy for about 6-12 months.
Subject(s)
Puberty, Precocious/physiopathology , Sexual Maturation , Child, Preschool , Female , HumansABSTRACT
A 5-year-old girl with McCune-Albright syndrome, was observed over a 7-year period. She presented with gonadotrophin-independent puberty and later developed gonadotrophin-dependent puberty. Hormonal signs of central puberty remained unchanged over the last 2 years.
Subject(s)
Endocrine System Diseases/blood , Fibrous Dysplasia of Bone/blood , Pigmentation Disorders/blood , Puberty, Precocious/blood , Child, Preschool , Female , Follicle Stimulating Hormone/blood , Humans , Luteinizing Hormone/blood , SyndromeABSTRACT
Follow up of 40 girls with premature thelarche showed that where this disorder occurred before age 2 years it usually regressed completely, thus representing a transient and isolated phenomenon. Premature thelarche after age 2 years persisted more frequently, however, and represented the first sign of sexual development, generally leading to simple early puberty.
