Are the Effects of Resistance Exercise on Pain and Function in Knee and Hip Osteoarthritis Dependent on Exercise Volume, Duration, and Adherence? A Systematic Review and Meta-Analysis.

OBJECTIVE: The purpose of this study was to determine dose parameters for resistance exercise associated with improvements in pain and physical function in knee and hip osteoarthritis (OA) and whether these improvements were related to adherence. METHODS: We searched six databases, from inception to January 28, 2023, for randomized controlled trials comparing land-based, resistance exercise-only interventions with no intervention, or any other intervention. There were four subgroups of intervention duration: 0 to <3 months, 3 to 6 months, >6 to <12 months, ≥12 months. The between-group effect was calculated for immediate postintervention pain and physical function (activities of daily living [ADL] and sports/recreation [SPORT]). RESULTS: For both knee and hip, data from 280 studies showed moderate benefit for pain, physical function ADL, and physical function SPORT in favor of interventions 3 to 6 months. For the knee, there was also a moderate benefit for physical function ADL in favor of interventions >6 to <12 months. From 151 knee and hip studies that provided total exercise volume data (frequency, time, duration), there was no association between volume with the effect size for pain and physical function. A total of 74 studies (69 knee, 5 hip) reported usable adherence data. There was no association between adherence with the effect size for pain and physical function. CONCLUSION: In knee and hip OA, resistance exercise interventions 3 to 6 months (and for the knee >6 to <12 months) duration improve pain and physical function. Improvements do not depend on exercise volume or adherence, suggesting exercise does not require rigid adherence to a specific dose.

Improving muscle capacity utilization with a 12-week strengthening program for females with symptomatic knee osteoarthritis.

BACKGROUND: Strengthening exercise improves symptoms in knee osteoarthritis (OA), but it remains unclear if biomechanical mechanisms contribute to this improvement. Muscle capacity utilization, which reflects the proportion of maximum capacity required to complete tasks, may provide insight into how strengthening exercise improves clinical outcomes in painful knee OA. PURPOSE: The purpose of this secondary analysis was to determine if a 12-week strengthening intervention reduced muscle capacity utilization during walking, squat and lunge tasks in females with painful knee OA. METHODS: Data from 28 females (age 59.6 ± 6.2 years old; body mass index 29.1 ± 4.7 kg/m2) with clinical knee OA were included. Participants completed a strengthening intervention 3 times per week for 12 weeks. Knee extensor isometric torque was measured on a commercial dynamometer; peak values from three exertions were averaged. Peak KFM was extracted and averaged from five walking trials. Mean KFM was extracted and averaged from three trials for each of static lunges and squats. Muscle capacity utilization was the ratio of mean peak KFM to peak extensor torque for walking; and mean KFM to peak extensor torque for squats and lunges. Paired t-tests determined differences between peak extensor torque, peak KFM and muscle capacity utilization from pre to post intervention (p < 0.05). RESULTS & SIGNIFICANCE: Peak extensor torque increased at follow up (p = 0.02). Peak KFM during walking decreased (p = 0.005). Muscle capacity utilization during walking (p = 0.008) and squat (p = 0.002) decreased. Mean KFM and muscle capacity utilization during lunge remained unchanged from pre to post intervention. The reduction in muscle capacity utilization at follow up indicates the strengthening intervention produced a decrease in proportion of the maximal capacity a participant used to complete walking and squat tasks. Strengthening both increases maximal muscle capacity and decreases the net moment required during daily tasks in knee OA.

Examining the Effect of Time-From-Treatment on Activities of Daily Living Kinematics in Breast Cancer Survivors.

Breast cancer affects one in 8 females with a 5-year survival rate of 89%. Up to 72% of breast cancer survivors have trouble with activities of daily living (ADL) following treatment. Increased time-from-treatment improves some measures of function, yet ADL limitations persist. Therefore, this study assessed the effect of time-from-treatment on upper extremity kinematics during ADLs in breast cancer survivors. Twenty-nine female breast cancer survivors were divided into 2 groups: <1 year (n = 12) and 1-2 years (n = 17) from treatment. Kinematics were collected during 6 ADL tasks, and humerothoracic joint angles were quantified. A 2-way mixed analysis of variance assessed the effects of time-from-treatment and arm on maximum angles for each ADL. Decreased maximum angle existed for breast cancer survivors with increased time-from-treatment during all ADLs. Breast cancer survivors in the 1-2 years group used ∼28° to 32° lower elevation, ∼14° to 28° lower axial rotation, and ∼10° to 14° lower plane of elevation range across tasks. Decreased ranges of arm movement during ADLs with increased time-from-treatment may reflect compensatory movement strategies. Recognizing this shift in strategies and accompanying underlying disease progression can help inform responses to functional performance limitations in breast cancer survivors as delayed effects are present posttreatment.

Variation of muscle recruitment during exercises performed below horizontal arm elevation that target the lower trapezius: A repeated measures cross-sectional study on asymptomatic individuals.

The gold standard exercise for recruitment of the lower trapezius is the Y prone exercise which is performed above 90° of shoulder elevation. However, clinicians often prescribe exercises that avoid high elevation postures during early stages of rehabilitation. Comparatively little data exists on relative muscle recruitment during lower arm elevation exercises. This study examined the EMG activity of four shoulder girdle muscles during four exercises accomplished below 90° of shoulder elevation and compared them to the Y prone while considering sex effects. Variance across exercises of the ratio between upper trapezius and lower trapezius was also explored. 32 healthy participants completed standardized muscle-specific MVCs and two repetitions of each exercise. The side lying external rotation and the wall slide exercises produced the highest peak EMG for the lower trapezius, both 33 and 29% lower than the Y Prone. For the upper trapezius to lower trapezius ratio, the side lying external rotation elicited the lowest value, followed by the Y prone and wall slide (53 and 59% respectively higher). Sex influenced some EMG values, typically interacting with exercise type. Thus, side lying external rotation and the wall slide are recommended for targeting the lower trapezius muscle during early rehabilitation.

An evaluation of upper limb strength and range of motion of breast cancer survivors immediately following treatment.

BACKGROUND: There is a growing number of breast cancer survivors from improved cancer treatments. However, treatments often impair upper limb function, specifically range of motion and strength, reducing quality of life and function. The primary purpose of this study was to quantify differences in strength and range of motion following treatment. The secondary purpose aimed to measure the activation of each upper limb muscle in the completion of tasks. METHODS: 29 breast cancer survivors were categorized into two groups based on time-since-treatment: 1) up to 1-year post-treatment, and 2) 1 to 2 years post-treatment. Participants completed maximal strength and range of motion tasks. During trials eight muscles were monitored bilaterally. Maximal force output was taken during strength trials, and kinematics were monitored during range of motion trials. A 2 by 2 mixed ANOVA (limb (affected, unaffected) x time-since-treatment) examined interaction and main effects of these factors on task peak force, angle and mean activation. FINDINGS: Time-since-treatment influenced strength (flexion, extension, internal and external rotation) and range of motion (flexion, scapular abduction), wherein the group further from treatment had 11.5-15.5° less range of motion and 27.7-43.6 N less force production. A main effect of time-since-treatment influenced muscular behaviours during both tasks, where activation was higher in the group 1-2 years from treatment. INTERPRETATION: Effects of treatment may manifest in a delayed manner whereby strength and range of motion are reduced in breast cancer survivors to a greater extent in those who are past 1 year of treatment cessation.

Upper extremity muscle activity and joint loading changes between the standard and powerlifting bench press techniques.

The bench press is a common activity found in many exercise regimens. Powerlifters often adopt non-standard techniques to potentially enhance maximal capability. The purpose of this research was to examine muscle activation and joint loading differences between the powerlifting (Arch) and standardised techniques. Twenty experienced male lifters completed lifts at an instructed cadence in the arch and the National Strength and Conditioning Association standard techniques at 25%, 50% and 75% of their self-reported one rep maximum. The arch technique increased latissimus dorsi mean and peak activation (p < 0.0001), generating activation of approximately 13% maximal voluntary contraction, regardless of percentage of the one rep maximum lifted. The standardised technique resulted in integrated shoulder moments that were 8% larger (p < 0.0001). This latissimus dorsi activation paired with decreased shoulder loading in the arch technique likely acts to minimise the amount of time spent in the "sticking region", where most lift efforts fail. It is possible to use this technique to increase latissimus dorsi activation, without increasing overall shoulder loading. The technique-specific differences can be used in performance or rehabilitation-based programmes to increase muscular output of some muscles without increasing overall loading.

The influence of posture variation on electromyographic signals in females obtained during maximum voluntary isometric contractions: A shoulder example.

Surface electromyography (sEMG) is commonly used to estimate muscle demands in occupational tasks. To allow for comparisons, sEMG amplitude is normalized to muscle specific maximum voluntary contractions (MVCs) performed in a standardized set of postures. However, maximal sEMG amplitude in shoulder muscles is highly dependent on arm posture and therefore, normalizing task related muscular activity to standard MVCs may lead to misinterpretation of task specific muscular demands. Therefore, the purpose of this study was to investigate differences in commonly monitored shoulder muscles using normalized sEMG amplitude between maximal exertions at different hand locations and across force exertion directions relative to standard MVCs. sEMG was recorded from the middle deltoid, pectoralis major sternal head, infraspinatus, latissimus dorsi, and upper trapezius. Participants completed standardized muscle-specific MVCs and two maximal exertions in 5 hand locations (low left, low right, high left, high right, and central) in each of the four force directions (push, pull, up, and down). Peak sEMG was analyzed in the direction(s) that elicited the highest signal for each muscle. All muscles differed by location (p < 0.05). Latissimus dorsi had the greatest activation during pulls (32-135% MVC); upper trapezius and middle deltoid while exerting upwards (73-103% and 42-78% MVC, respectively); infraspinatus while pushing (38-79% MVC); and pectoralis major activation was the highest during downwards exertions (48-84% MVC). Normalization of location specific maximal exertions to standard muscle specific MVCs underestimated maximal activity across 90% of the tasks in all shoulder muscles tested, except for latissimus dorsi where amplitudes were overestimated in low right hand location. Normalization of location specific muscle activity to standard muscle specific MVCs often underestimates muscle activity in task performance and is cautioned against if the goal is to accurately estimate muscle demands.

Wrapping technique and wrapping height interact to modify physical exposures during manual pallet wrapping.

Occupational tasks often involve musculoskeletal demands that contribute to injury risk. In pallet wrapping tasks, 36% of workplace claims involve over exertion and repetitive exposures (Workplace Safety and Prevention Services, 2012). Tools that modify how the wrap is handled by workers have been introduced to help mitigate over exertion and extreme postures wherever possible. A novel device has been introduced that places the required tension on the roll to mitigate these factors. However, the effect of reducing the necessary tension on the roll during pallet wrapping in limiting muscular demand and extreme postures is unknown. Fourteen healthy university aged participants completed 12 wrapping trials on a simulated pallet (2 repetitions of 2 wrapping techniques (device, hand wrapping) at 3 wrapping heights (low, medium, high)). Surface electromyography (sEMG) was measured on 6 shoulder and 2 low back muscles; anterior and middle deltoids, biceps brachii, infraspinatus, supraspinatus, upper trapezius, and erector spinae (T8 & L3). Kinematic data were collected for the torso and upper extremity and global to torso, and torso to upper arm angles were computed. Repeated measures ANOVAs were performed for the following experimental factors: 1) technique used (device or hand wrapping) and 2) the wrapping height (low, medium, high) for each muscle (8), angle (5), rating of perceived discomfort (1) and rating of perceived exertion (1). Pallet wrapping without a device required greater trunk flexion at lower heights and thoracohumeral elevation at higher wrapping heights as compared to using the device. Muscular activation increased when using the device, specifically at the higher and lower heights. Posture and muscular demands during pallet wrapping tasks are sensitive to both wrapping technique and wrapping height. Ergonomics interventions such as this device may mitigate postural risks associated with manual material handling tasks.

Workstation configuration and container type influence upper limb posture in grocery bagging.

INTRODUCTION: Repetitive movements and awkward postures are two persistent injury risk factors for grocery store cashiers. Due to the recent rise in popularity of environmentally-friendly grocery bagging options, current recommendations for cashiers are likely outdated. Correspondingly, the objective of this study was to examine the effects of cashier-specific work demands, workstation configuration, and container type on upper limb postures during typical job activities. METHODS: Fifteen experienced cashiers bagged groceries at varying combinations of workstation height (low, medium, high) and container type (reusable bins, reusable bags, plastic bags). Upper limb movement was quantified with motion capture and amplitude probability distribution functions of humeral elevation and humeral axial internal rotation were used to assess the static (10th percentile), median (50th percentile), and peak (90th percentile) postural demands, which were then interpreted in the context of existing postural guidelines. RESULTS: High workstation height and reusable bags increased right arm elevation at peak posture by 15.7° compared to the low workstation height and reusable bin combination. However, reusable bins increased internal rotation demands of the right arm by 4.3° compared to other container types. Left arm elevation and internal rotation were consistently lower than right arm angles. CONCLUSION: Cashiers are encouraged to adjust the workstation to decrease the arm elevation and internal rotation required by higher workstation heights and tall containers, and to use both arms for scanning and packing, when possible, to reduce undesirable arm postures.

The effect of aging and contextual information on manual asymmetry in tool use.

Healthy aging affects manual asymmetries in simple motor tasks, such as unilateral reaching and aiming. The effects of aging on manual asymmetries in the performance of a complex, naturalistic task are unknown, but are relevant for investigating the praxis system. This study examined how aging influences manual asymmetry in different contexts in a tool manipulation task. Fifty healthy, right-hand-dominant young (N = 29; 21.41 ± 2.87 years), and elderly (N = 21; mean: 74.14 ± 6.64 years) participants performed a 'slicing' gesture in response to a verbal command in two contexts: with (tool) and without the tool (pantomime). For interjoint relationships between shoulder plane of elevation and elbow flexion, a HAND × AGE × CONTEXT interaction existed (F1,43 = 4.746, p = 0.035). In pantomime, interjoint control deviated more in the left (non-dominant) than the right (dominant) limb in the elderly adult group (Wilcoxon, p = 0.010). No such differences existed in the young adult group (Wilcoxon, p = 0.471). Furthermore, contextual information reduced interjoint deviation in young adults when the task was performed with the right (dominant) hand (Wilcoxon, p = 0.001) and in the elderly adults when the task was performed with the left (non-dominant) hand (Wilcoxon, p = 0.012). The presence of the tool did not reduce interjoint deviation for the right hand in the elderly group (Wilcoxon, p = 0.064) or the left hand in the young group (Wilcoxon, p = 0.044). Deviation within trials (i.e., intrasubject deviation) in elbow flexion was higher in the elderly relative to the young adult group (p = 0.003). Finally, resultant peak velocities were smaller (p = 0.002) and cycle duration longer (p < 0.0001) in the elderly adult group. This study provides novel evidence that aging affects manual asymmetries and sensorimotor control in a naturalistic task and warrants that aging research considers the context in which the task is performed.

Fatigue-induced glenohumeral and scapulothoracic kinematic variability: Implications for subacromial space reduction.

Superior humeral head translation and scapula reorientation can reduce the subacromial space. While these kinematic abnormalities exist in injured populations, the effect of muscle fatigue is unclear. Additionally, these mechanisms were typically studied independently, thereby neglecting potential covariance. This research evaluated the influence of upper extremity muscle fatigue on glenohumeral and scapulothoracic kinematics and defined their relationship. Radiography and motion tracking systems captured these kinematic relationships, during scapula plane elevation, both before and after fatigue. Fatigue-induced changes in humeral head position, scapular orientation and the minimum subacromial space width were measured. High inter-subject variability existed for each measure which precluded identification of mean differences at the population level. However, significant scapular upward rotation occurred following fatigue (p=0.0002). Despite similar population mean results, between 39% and 57% of participants exhibited fatigue-related changes in disadvantageous orientations. Additionally, correlations between measures were generally fair (0.21-0.40) and highly dependent on elevation, likely attributed to the variable fatigue responses. Overall, the data confirms that fatigue-induced changes in kinematics poses highly variable risk of subacromial impingement syndrome across individuals. Thus, solely considering the "average" or mean population response likely underestimates potentially injurious fatigue consequences.

Effects of overhead work configuration on muscle activity during a simulated drilling task.

Overhead work is a known catalyst for occupational shoulder injury. Industrial workers must often adopt awkward overhead postures and loading profiles to complete required tasks, potentially elevating injury risk. This research examined the combined influence of multiple overhead working parameters on upper extremity muscular demands for an industrial drilling application. Twenty-two right-handed males completed 24 unilateral and bilateral overhead work exertions stratified by direction (upward, forward), point of force application (15, 30 and 45 cm in front of the body), and whole-body posture (seated, standing). The dependency of electromyographic (EMG) activity on several factors was established. Significant two-way interactions existed between point of force application and direction (p < 0.0001) and direction and whole body posture (p < 0.0001). An average increase in muscular activity of 6.5% maximal voluntary contraction (MVC) occurred for the contralateral limb when the bilateral task was completed, compared to unilateral tasks, with less than a 1% MVC increase for the active limb. These findings assist evidence-based approaches to overhead tasks, specifically in the construction industry. A bilateral task configuration is recommended to reduce glenohumeral stability demands. As well, particularly for tasks with a far reach distance, design tasks to promote a forward directed exertion. The considerable inter-subject variability suggests that fixed heights are not ideal, and should be avoided, and where this is not possible reaches should be reduced.