ABSTRACT
INTRODUCTION: Prader-Willi syndrome (PWS) is a rare genetic multisystemic disease that is the most common inherited cause of severe childhood obesity. PWS patients are prone to significant oral and systemic health issues that detrimentally affect quality of life and decrease longevity. This report documents full-mouth pre-prosthetic surgical and restorative care in an adult PWS patient. CASE REPORT: The patient, a 29-year-old male, presented to the clinic accompanied by his guardians (parents) with the chief complaint that "My Teeth are breaking down and I would like to get them fixed". Periodontal and prosthetic comprehensive clinical and radiographic exams revealed a severely worn dentition, deep anterior overbite, altered passive eruption with generalized biofilm-induced gingivitis, and altered occlusal vertical dimension. Full mouth crown lengthening surgery combined with full mouth prosthodontic reconstruction was performed under parenteral sedation and local anesthesia. Completion of treatment was successful, and the patient was placed on a 3-month periodontal maintenance interval. DISCUSSION: Full mouth periodontal surgical and prosthodontic reconstruction on a PWS patient has not previously been reported in the literature. This case underscores the potential need for complex dental care in patients with this syndrome.
ABSTRACT
STATEMENT OF PROBLEM: Long-term data are sparse on the use of metal-acrylic resin implant-supported fixed complete dentures. PURPOSE: The purpose of this retrospective clinical study was to assess the prosthetic survival and complication rate in patients treated with metal-acrylic resin implant-supported fixed complete dentures (ma-IFCDs). MATERIALS AND METHODS: The patient record system at the Dental College of Georgia was searched from 2006 to 2020 to identify all patients treated with ma-IFCDs by the graduate prosthodontic and general practice residents during this time. Variables collected were date of delivery of the prosthesis, arch treated (maxilla, mandible), date of the last visit, status of the opposing arch (complete arch fixed implant-supported prosthesis, complete denture, removable implant-supported overdenture, teeth and removable partial denture, teeth and implants, teeth only), date of replacement, and reason for replacement. Reasons for replacement were grouped as fracture of the framework, implant loss, patient-related concerns, catastrophic acrylic resin fracture (judged to be beyond predictable repair by the clinician), and extensive occlusal wear (judged to have worn to the point of requiring replacement). RESULTS: A total of 84 arches in 55 patients who met the inclusion criteria were identified from the electronic health review. Of the 84 complete arch prostheses, 43 were maxillary and 41 were mandibular. The median follow-up time was 2.8 years (interquartile range [IQR] 0.95, 4.65). A total of 31 of the 84 arches were identified as having failed, requiring replacement. The most frequent reason for replacement was catastrophic fracture of the acrylic resin (61%), followed by excessive occlusal wear (19%). It was found that 13% of the failures were associated with patient-related concerns, and 7% with the loss of an implant. Survival rates were analyzed based on the opposing arch. The combined survival rate (Kaplan-Meier, log-normal modeling) for ma-IFCDs was 54% at 5 years (95% confidence interval [CI] 42%, 66%) and 32% at 10 years (95% CI 20%, 47%). CONCLUSIONS: Mid- to long-term survival rates for ma-IFCDs are concerningly low. The findings suggest that the status of the opposing arch plays a role in the survival rate of ma-IFCDs. The most common complication was catastrophic fracture of the acrylic resin superstructure, followed by wear of the acrylic resin denture teeth.
