Subject(s)
Eye Injuries, Penetrating/therapy , Adolescent , Adult , Female , Follow-Up Studies , Fundus Oculi , Humans , MaleABSTRACT
This paper presents the three year results of radial keratotomy (RK) surgery on 51 of the first 59 consecutive eyes at the National University Hospital in Singapore. Before surgery, uncorrected visual acuity was worse than 6/24 in all eyes with 33.3% worse than 6/60. The average pre-operative spherical equivalent (SE) was -4.56 Dioptres(D). Three years after surgery the mean SE was -0.66D, a change of 3.9D; and 72.5% of eyes were within 1D of emmetropia. 70.6% had uncorrected visual acuity of at least 6/12 with no eyes having worse than 6/60 visual acuity. Analysis based on levels of pre-operative myopia showed that the best visual and refractive results were obtained in patients with SE of -6D or less. None of the patients were troubled by complications such as glare, fluctuating vision, irritation and discomfort three years after surgery. Our results indicate that RK surgery is safe and effective through the three years and more following surgery.
Subject(s)
Keratotomy, Radial/statistics & numerical data , Adult , Age Factors , Astigmatism/surgery , Follow-Up Studies , Hospitals, University , Humans , Keratotomy, Radial/adverse effects , Myopia/physiopathology , Myopia/surgery , Refraction, Ocular , Retrospective Studies , Singapore/epidemiology , Visual AcuityABSTRACT
Two sisters aged about 40 years presented with a recent moderate reduction in visual acuity and pale optic discs. The nonconsanguineous parents, 7 other siblings and all other family members have normal vision. This strongly indicates a hereditary, autosomal recessive origin. A primary ganglion cell pathology is strongly suspected because of the significant attenuation of the early component of the onset/offset visual-evoked potential in the presence of little change in the potential to a pattern reversal stimulus.
Subject(s)
Optic Atrophy/genetics , Optic Atrophy/physiopathology , Retinal Ganglion Cells , Adult , Age of Onset , Electroretinography , Evoked Potentials, Visual , Female , Genes, Recessive , Humans , Mutation , Optic Atrophy/pathology , PedigreeABSTRACT
We report two cases of ectopic cilia originating from the iris without any convincing history of injury to the eye. One required surgical removal to prevent further endothelial and lens damage developing over a five-year observation period.
Subject(s)
Eyelashes/abnormalities , Iris/abnormalities , Adolescent , Adult , Eyelashes/pathology , Eyelashes/surgery , Female , Humans , Iris/pathology , Iris/surgery , MaleSubject(s)
Needles , Suture Techniques/instrumentation , Humans , Ophthalmologic Surgical ProceduresABSTRACT
The variability of the response of the rabbit eye to topical 1% dexamethasone has been shown in two groups of 20 young albino rabbits each (total 40) tested in succession. The pressure anomalously fell significantly (but by only 1 mm Hg) in both groups in the first 4 weeks of administration, but not in subsequent weeks. Mifepristone (RU 486), a peripheral antagonist of dexamethasone and progesterone, reduced the pressure significantly, again by only 1 mm Hg, in the first group of 20 rabbits, not the second. Accordingly, no conclusion was possible on the originating question: does pre-treatment with mifepristone prevent the dexamethasone-induced rise in rabbit intra-ocular pressure?
