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1.
Br J Anaesth ; 124(3): 261-270, 2020 03.
Article in English | MEDLINE | ID: mdl-31864719

ABSTRACT

BACKGROUND: The Duke Activity Status Index (DASI) questionnaire might help incorporate self-reported functional capacity into preoperative risk assessment. Nonetheless, prognostically important thresholds in DASI scores remain unclear. We conducted a nested cohort analysis of the Measurement of Exercise Tolerance before Surgery (METS) study to characterise the association of preoperative DASI scores with postoperative death or complications. METHODS: The analysis included 1546 participants (≥40 yr of age) at an elevated cardiac risk who had inpatient noncardiac surgery. The primary outcome was 30-day death or myocardial injury. The secondary outcomes were 30-day death or myocardial infarction, in-hospital moderate-to-severe complications, and 1 yr death or new disability. Multivariable logistic regression modelling was used to characterise the adjusted association of preoperative DASI scores with outcomes. RESULTS: The DASI score had non-linear associations with outcomes. Self-reported functional capacity better than a DASI score of 34 was associated with reduced odds of 30-day death or myocardial injury (odds ratio: 0.97 per 1 point increase above 34; 95% confidence interval [CI]: 0.96-0.99) and 1 yr death or new disability (odds ratio: 0.96 per 1 point increase above 34; 95% CI: 0.92-0.99). Self-reported functional capacity worse than a DASI score of 34 was associated with increased odds of 30-day death or myocardial infarction (odds ratio: 1.05 per 1 point decrease below 34; 95% CI: 1.00-1.09), and moderate-to-severe complications (odds ratio: 1.03 per 1 point decrease below 34; 95% CI: 1.01-1.05). CONCLUSIONS: A DASI score of 34 represents a threshold for identifying patients at risk for myocardial injury, myocardial infarction, moderate-to-severe complications, and new disability.


Subject(s)
Exercise Tolerance/physiology , Health Status Indicators , Preoperative Care/methods , Adult , Aged , Biomarkers/blood , Female , Health Status , Humans , Male , Middle Aged , Myocardial Infarction/etiology , Myocardial Infarction/mortality , Natriuretic Peptide, Brain/blood , Peptide Fragments/blood , Postoperative Complications/mortality , Prognosis , Prospective Studies , Risk Assessment , Risk Factors , Self Report , Surveys and Questionnaires
2.
Anaesthesia ; 51(6): 561-4, 1996 Jun.
Article in English | MEDLINE | ID: mdl-8694210

ABSTRACT

A new, rigid intubating fibrescope, the Upsherscope, was evaluated in clinical practice. Intubation was attempted in 200 adult patients and was successful in 191, with a median intubation time of 38 s, range 14-154 s. Intubation was straightforward in just under half of the patients. Difficulties were encountered in picking up the epiglottis, in passing the tracheal tube between the vocal cords and with secretions interfering with the view. In two patients known to be difficult to intubate, the Upsherscope was successful in one patient using an awake technique and failed in the other.


Subject(s)
Anesthesia, General , Intubation, Intratracheal/methods , Laryngoscopes , Adolescent , Adult , Aged , Aged, 80 and over , Equipment Design , Evaluation Studies as Topic , Female , Humans , Male , Middle Aged , Time Factors
3.
Ann R Coll Surg Engl ; 70(6): 386-91, 1988 Nov.
Article in English | MEDLINE | ID: mdl-3061355

ABSTRACT

Cardiac tamponade is an uncommon problem in a district general hospital. Three patients were admitted to the intensive therapy unit at Northampton General Hospital with tamponade in a 7-week period, each with a different underlying aetiology. Their case histories are presented and the management in the light of these described. The aetiology, physiology, clinical signs and investigations leading to the diagnosis are considered. In the discussion the opportunity is taken to review the recent literature on the subject.


Subject(s)
Cardiac Tamponade/surgery , Adult , Anesthesia, General , Cardiac Tamponade/diagnosis , Cardiac Tamponade/diagnostic imaging , Catheterization, Central Venous/adverse effects , Echocardiography , Female , Heart Atria/injuries , Heart Injuries/complications , Humans , Male , Middle Aged , Pericardial Effusion/complications , Radiography , Thoracic Injuries/complications , Wounds, Penetrating
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